Clinical trials
Overweight and Obese Adults clinical trials
Below are recruiting overweight and obese adults clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05843318Recruiting
Water intake and weight control for adults 50+
This study tests whether adjusting how much plain drinking water you drink can help with weight control in older adults. You may be asked to follow a structured plan and participate in activities as part of the research.
Blacksburg, VirginiaAges 50 years+ - NCT07724340RecruitingPhase 2
Study of AT673 plus semaglutide for type 2 diabetes and weight loss
This study tests a new medication called AT673 combined with semaglutide (Wegovy) to help people with type 2 diabetes and overweight or obesity lose weight and improve blood sugar. It is for people who have tried diet and exercise to lose weight but haven't had success.
Chandler, ArizonaAges 18 years+ - NCT06893016RecruitingPhase 3
Study of RAY1225 for adults with obesity or overweight
This trial tests a new medicine called RAY1225 to help people lose weight. If you have obesity or are overweight with related health conditions, you may be able to join.
BeijingAges 18 years+ - NCT07205432RecruitingPhase 1
Testing XTL6001 in healthy and obese adults
This early-stage trial tests a new medication (XTL6001) in healthy and obese adults to see if it is safe. It is for people who are not diabetic, have no history of certain stomach, pancreas, or gallbladder problems, and have a BMI up to 40.
Beijing, Beijing MunicipalityAges 18–65 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT06076187Recruiting
How older adults digest protein after weight loss surgery
This study looks at how well older adults break down protein after bariatric surgery. It compares people who had surgery one to ten years ago with those who didn't, to understand protein needs.
Leuven, Flemish BrabantAges 18 years+ - NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65 - NCT07163455Recruiting
Time-restricted eating for keeping weight off
This study tests if eating only during certain hours of the day helps people maintain weight loss after a structured program. It may be a good fit if you are overweight or have related health issues and want a simple eating schedule to follow.
Beijing, Beijing MunicipalityAges 18–65 - NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07504068Recruiting
Exercise and supplement for metabolic health in overweight adults
This trial tests whether a combination of physical exercise and a nutritional supplement can improve body composition, metabolism, and overall health in adults who are overweight and have early signs of metabolic problems. It may help you if you are looking for a non-drug approach to boost your health.
Valencia, ValenciaAges 50–65 - NCT07511205RecruitingPhase 1
Study of AZD1043 for overweight or obesity
This trial tests a new medicine called AZD1043 in healthy adults who are overweight or have obesity. It aims to see if the medicine is safe and how the body handles it.
Glendale, CaliforniaAges 18–65 - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT07641361Recruiting
Staying Hydrated to Feel Better on GLP-1 Medication
This study tests whether drinking more water helps reduce uncomfortable side effects (like nausea and vomiting) when you first start taking GLP-1 medications for weight loss or diabetes. You'll be asked to follow a hydration plan and report how you feel.
Buffalo, New YorkAges 18–60 - NCT05713448Recruiting
Check how common overweight is in adults with type 1 diabetes
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
LeuvenAges Any age - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Dothan, AlabamaAges 18–70 - NCT07316179Recruiting
Predicting breathing tube placement in weight-loss surgery
This study compares two methods—a standard risk score (El Ganzouri index) and an ultrasound exam—to predict how easy it will be to place a breathing tube during weight-loss surgery. The goal is to find the best way to keep patients safe during anesthesia.
Antalya, AntalyaAges 18–65 - NCT06897241Recruiting
How different starches affect your metabolism
This study tests how your body responds to different types of starch (quick, slow, and resistant). You will follow special diet plans and use monitoring devices to understand your personal metabolic reactions.
Gothenburg, Västra Götaland CountyAges 30–75 - NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT07717658Recruiting
Family weight wellness program for teens and parents
This study tests a weight wellness program that uses food support and group medical visits for teens and their parents. It aims to help families adopt healthier habits together over 12 months.
Boston, MassachusettsAges 12–17
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Common questions
- Are there clinical trials for overweight and obese adults?
- Yes. Clin2 currently lists 139 recruiting overweight and obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight and obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight and obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.