Clinical trials
Overweight and Obese Adults clinical trials
Below are recruiting overweight and obese adults clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06273072RecruitingPhase 2
Metformin for asthma in overweight adults
This trial tests whether the diabetes drug metformin can help people with asthma who are also overweight or obese. The goal is to see if it improves asthma control and reduces the need for rescue medications.
Baltimore, MarylandAges 18 years+ - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07036562Recruiting
Time-restricted eating and high-intensity interval training for people with overweight
This study tests whether combining time-restricted eating (limiting when you eat) with high-intensity interval training (short, intense bursts of exercise) can improve health in people who are overweight. It may help you lose weight and improve your body's ability to use sugar and fat.
TrondheimAges 18–50 - NCT06604650Recruiting
Park-based health program for older adults in Miami
This study looks at how community park programs can help older adults stay healthy. It will use information already collected from people who are already part of the Miami-Dade Active Older Adults study.
Miami, FloridaAges 50–95 - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT07514260RecruitingPhase 1
Safety study of ABBV-295 injections in Japanese adults with overweight
This is an early-stage safety study testing a new injectable medication (ABBV-295) in healthy Japanese adults who are overweight or have obesity. The study measures how well the body tolerates the drug and how it moves through the body.
Anaheim, CaliforniaAges 18–65 - NCT07757087RecruitingPhase 1
Study on energy use after weight loss
This study tests a new medicine to see how it affects the body's energy use after losing weight. It compares the medicine to a low-calorie diet or a placebo (a pill with no active ingredient) in adults with obesity.
Aarhus NAges 18 years+ - NCT07363616Recruiting
Health-focused programs for adults with higher body weight
This study tests different programs that focus on improving health without focusing on weight loss. It is for adults with higher body weight who want to feel healthier, not necessarily to lose weight.
Providence, Rhode IslandAges 18 years+ - NCT07018544Enrolling by invitation
Wegovy safety and effectiveness study in Korea
This study watches how Wegovy (semaglutide) works and its side effects when given by doctors to patients with obesity or overweight in South Korea. It is not testing a new drug, but collecting information from routine care.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06949280Recruiting
Peanuts, weight loss, and bone health study
This study tests whether eating peanuts daily during weight loss affects bone health in adults aged 50 to 75.
New Brunswick, New JerseyAges 50–75 - NCT07518875Enrolling by invitation
Online weight loss program for Arab adults
This study tests an online dietary weight loss program designed for Arabic-speaking adults. You'll receive 12 educational sessions over 6 months to help manage weight and improve health conditions like diabetes or high blood pressure.
Mecca, Mecca RegionAges 18–75 - NCT07368777Recruiting
Genetics-based diet counseling vs standard diet for weight loss
This trial compares two types of diet counseling—one based on your genetic makeup and the other standard advice—to see which helps more with weight loss and reducing body fat. It is for adults who are overweight or obese and willing to follow a diet program.
MarousiAges 18–65 - NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT06924320RecruitingPhase 1/Phase 2
Study of two medicines for weight loss and diabetes
This study tests two investigational medications, MET233 and MET097, in people with obesity or overweight, with or without type 2 diabetes. It aims to see if the combination can help with weight loss and blood sugar control.
Cypress, CaliforniaAges 18–75 - NCT07239167Enrolling by invitation
Weight change study for adults with obesity
This study looks at how weight changes affect health in adults with obesity. You may qualify if you have a high BMI and are willing to try a weight loss program.
Taipei, Zhongzheng DistAges 18 years+ - NCT06645470Recruiting
Muscle and movement study for weight loss medications
This study looks at how anti-obesity medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) affect your muscles and movement. It may help researchers understand how to combine these drugs with exercise for better health.
Kansas City, KansasAges 18 years+ - NCT07627074Recruiting
Real-world weight loss study with semaglutide
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
Seattle, WashingtonAges 18 years+ - NCT06724406Recruiting
Family-centered weight loss for Black adults
This trial tests a weight loss program for Black adults and a family partner. You and a family member work together to lose weight with support from a smartphone or computer.
Chapel Hill, North CarolinaAges 18–75 - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT07438444RecruitingPhase 4
Study of Tirzepatide for Type 2 Diabetes or Obesity
This trial tests a new medicine called tirzepatide to see if it helps people with type 2 diabetes or obesity. It is for adults in India who have not used insulin before or meet specific weight and health conditions.
AhmedabadAges 18 years+ - NCT06124456Recruiting
Vigorous vs. moderate exercise for liver fat reduction
This study compares high-intensity exercise to moderate-intensity exercise to see which is better at reducing fat in the liver for people with obesity and fatty liver disease.
Hong KongAges 18–69 - NCT06937060RecruitingPhase 3
Semaglutide for psoriasis and obesity
This trial tests if semaglutide, a medicine used for diabetes and weight loss, can help people with both psoriasis and obesity. You may qualify if you have moderate to severe psoriasis, a high body weight, and are of Chinese descent.
Hong KongAges 18–75
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Common questions
- Are there clinical trials for overweight and obese adults?
- Yes. Clin2 currently lists 139 recruiting overweight and obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight and obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight and obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.