Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05674799Recruiting
Program to lower future obesity and diabetes risks
This trial tests a lifestyle and coaching program (NDPP-NextGen) to help reduce the chances of obesity and diabetes risk passing to the next generation. It’s for people planning a pregnancy soon and who may be at higher risk due to body weight.
Winston-Salem, North CarolinaAges 18–39 - NCT05097365Enrolling by invitation
Testing a methyl-donor supplement to study lupus metabolism
This study looks at whether a “methyl-donor” nutrient supplement changes metabolism (methylation) in people with lupus who are also in the childbearing age range and have low-to-moderate disease activity. It may help researchers understand why lupus acts differently in some people and how diet-related pathways could affect symptoms.
São PauloAges 18–45 - NCT04805502Recruiting
Pregnancy exercise program to help prevent childhood obesity
This trial studies whether a structured exercise program during pregnancy can help lower the risk of childhood obesity. If you qualify, you may be asked to exercise during early pregnancy and share information with the research team.
Greenville, North CarolinaAges 18–45 - NCT03880422Recruiting
Exercise and nutrition for weight and frailty after prostate cancer treatment
This study tests whether a structured exercise and nutrition program can improve obesity-related frailty and overall function in people with advanced prostate cancer who are taking hormone therapy (ADT). It may help with strength, mobility, and healthier body weight during/after ADT.
Buffalo, New YorkAges 18 years+ - NCT07556679Enrolling by invitation
Play2Control: Reducing screen time for teens with type 2 diabetes
This study tests whether helping families spend less time watching TV or using screens can improve blood sugar control in children and teens with type 2 diabetes. It may help you manage diabetes better by cutting down on screen time.
Miami, FloridaAges 5–21 - NCT03561766Recruiting
Pregnancy birth-cohort study for early pregnancy participants
This study follows pregnant people from early pregnancy to help researchers better understand health and outcomes over time. It’s mainly for those who plan to receive care and deliver at Shengjing Hospital in the Shenyang area.
Shenyang, LiaoningAges 18 years+ - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60 - NCT07870538RecruitingPhase 4
Matching weight-loss treatments to binge eating patterns
This study tests whether a medication called semaglutide, which is used for weight loss, works better for people who also have binge eating. It aims to find the best treatment based on brain and behavior differences.
LeuvenAges 18–65 - NCT06244888RecruitingPhase 2
Using new strategies to help maintain weight loss
This study tests a method to help people who have already lost weight keep it off. It uses a control systems engineering approach to provide personalized support.
Providence, Rhode IslandAges 18–70 - NCT06116435Recruiting
Lifestyle program for weight loss and physical activity
This study tests a lifestyle program to help people become more active and lose weight. It compares different types of support to see what works best.
Aurora, ColoradoAges 18–65 - NCT07842640RecruitingPhase 1
Injectable treatment for overweight and obesity
This study tests an injectable medication called ASC35 to see if it is safe and tolerable for people who are overweight or obese. It may help with weight management, though it is an early-stage trial focused on safety first.
Baltimore, MarylandAges 18–65 - NCT07844616Recruiting
Eggs, gut health, and metabolism study
This study looks at how eating whole eggs versus egg whites affects your gut bacteria, metabolism, and immune system. It aims to understand how eggs may influence health markers in people of different weight ranges.
Storrs, ConnecticutAges 18–50 - NCT07822061RecruitingPhase 3
Weight loss study for people with excess weight
This study tests an investigational medicine for weight loss in people with excess weight. It aims to see how effective the medicine is and may help you lose weight and improve health.
Sapporo, HokkaidoAges 18 years+ - NCT07809152Recruiting
Collagen supplements after weight-loss surgery: muscle and body image
This study tests whether taking collagen supplements after weight-loss surgery helps preserve muscle and improve how you feel about your body. It will compare people who take the supplement with those who don't.
Bursa, YıldırımAges 18–65 - NCT07806838Recruiting
Dietary supplements to preserve muscle during GLP-1 weight loss
This study looks at whether certain dietary supplements can help preserve muscle mass while you are taking a GLP-1 medication for weight loss. You would take the supplements or a placebo for a period while continuing your GLP-1 treatment, and the researchers will measure changes in your muscle and strength.
Los Angeles, CaliforniaAges 18 years+ - NCT07806383Enrolling by invitation
Effects of a sugar-based supplement on heart and gut health in overweight adults
This study tests a sugar-based supplement (a synbiotic) to see if it improves heart and metabolic health markers as well as gut health in people who are overweight but otherwise healthy. You will take the supplement for a period of time, and your health will be monitored.
NaplesAges 20–70 - NCT07793929RecruitingPhase 1
Kidney function and study drug levels
This study checks how different levels of kidney function affect the levels of a new investigational drug called Ribupatide in the blood. It helps doctors understand how the drug works in people with various kidney conditions.
Orlando, FloridaAges 18–85 - NCT07798557Recruiting
Lifestyle and diet support for weight and heart health
This study tests a program to help you improve your diet and lifestyle, which may reduce your risk for heart disease and help with weight loss. You will get support to make healthy changes over the next year.
Chicago, IllinoisAges 50–79 - NCT07789769Recruiting
Online weight loss program focusing on protein, fiber, and exercise
This study tests a 6-month online weight loss program that focuses on eating more protein and fiber and adding exercise—called the '30-30-30 Plan.' It's a chance to get support and guidance to help you reach your weight loss goals.
Addison, IllinoisAges 18–69 - NCT07789223Recruiting
Weight management study with natural supplements
This study tests a natural supplement (elénzia CONTROL®) to help with weight loss and metabolic health. Researchers want to see if it works for people who have never used GLP-1 medications or who have stopped using them.
Redditch, West MidlandsAges 25–65 - NCT07784699RecruitingPhase 1
Testing an experimental pill for weight loss in healthy or overweight adults
This study tests an experimental pill (GZC8072) for weight loss. It is a phase 1 trial, meaning it is one of the first times the drug is given to people, and the focus is on safety and how the body handles it. You would receive either a single dose (if you are healthy) or multiple doses (if you are overweight or obese) to see how the medication works.
BeijingAges 18–55 - NCT07785934RecruitingPhase 1
Testing a new weight management injection for drug interactions
This study tests a new injectable medication for weight management in people with overweight or obesity. It investigates how the drug interacts with other medications and checks its safety. Participation requires a 6-month commitment with regular study visits.
Hefei, AnhuiAges 18–45 - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT06265246Recruiting
Milk and yogurt for stronger bones in young adults
This study tests whether adding milk and yogurt to your diet can improve bone health and body composition. If you're a young adult with low calcium intake, you may qualify to join.
Saskatoon, SaskatchewanAges 19–30
Hear when a new Overweight or Obese Adults trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.