Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07684144RecruitingPhase 3
Long-term study of a weight-loss medication for people who completed an earlier trial
This study tests the long-term effects of a medication called maridebart cafraglutide for weight management. It is for people who already completed a 72-week study of this drug and want to continue treatment.
Gilbert, ArizonaAges 18–99 - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Anniston, AlabamaAges 18–99 - NCT07785934RecruitingPhase 1
Testing a new weight management injection for drug interactions
This study tests a new injectable medication for weight management in people with overweight or obesity. It investigates how the drug interacts with other medications and checks its safety. Participation requires a 6-month commitment with regular study visits.
Hefei, AnhuiAges 18–45 - NCT07710729RecruitingPhase 1
How UBT251 Affects Birth Control and Stomach Emptying
This study tests a new medicine, UBT251, to see if it affects how birth control pills work and how quickly food leaves the stomach. It is for women with overweight or obesity who cannot get pregnant.
Montreal, QuebecAges 18–65 - NCT06848491Recruiting
Smartphone weight loss programs for young adult cancer survivors
This study tests two different smartphone-based programs to help young adult cancer survivors lose weight. Participants are randomly assigned to one of two programs and use an app to track their progress.
Chapel Hill, North CarolinaAges 18–39 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT07631767Recruiting
Health Behavior Program for Night Shift Workers
This study tests a smartphone app designed to help night shift workers improve their sleep, eating habits, and overall health. You'll use the app to track and improve your wellness while working night shifts across Europe.
BremenAges 21 years+ - NCT07612527RecruitingPhase 2
Endoscopic Stomach Procedure for Weight Loss
This trial tests a minimally invasive procedure done through the mouth (no surgery) that reshapes the stomach to help with weight loss. It combines two techniques to reduce stomach function and may help people lose weight without traditional bariatric surgery.
CairoAges 18 years+ - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT05811624Recruiting
Lifestyle program for weight and chronic low back pain
This trial studies whether a lifestyle change program (often diet and activity habits) can reduce long-lasting low back pain in overweight or obese adults. It also aims to see if people can keep their usual care while adding the lifestyle program.
BrusselsAges 18–65 - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07526584Recruiting
Food Label Study in Indonesia
This study tests how different warning labels on packaged foods affect what people choose to buy in Indonesia. Researchers want to understand which label designs help people make healthier food choices.
Chapel Hill, North CarolinaAges 18 years+ - NCT07670884RecruitingPhase 3
Study of HRS9531 for weight loss in overweight or obese adults
This trial tests an oral medication, HRS9531, to help overweight or obese adults lose weight. It may be an option if you have been unable to lose enough weight through diet and exercise alone.
Zhengzhou, HenanAges 18–75 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07708064Recruiting
Preventing weight regain with a smartphone program
This study tests a smartphone-based program to help people who have lost weight keep it off or lose more. It uses personalized tips and check-ins to prevent giving up if you regain some weight.
Springfield, OregonAges 18–70 - NCT07351110Recruiting
Cervical cancer prevention for women with obesity or diabetes
This trial tests a program to help women with obesity or type 2 diabetes get cervical cancer screenings. It uses text messages or emails to remind and support you in getting screened.
Gainesville, FloridaAges 25 years+ - NCT07275697RecruitingPhase 4
Weight loss drug and heart ablation study for AFib
This trial tests whether a weight loss medication (semaglutide) given before and after a first-time heart ablation procedure for atrial fibrillation can improve outcomes. It is for people who are overweight or obese and have certain related health conditions.
StockholmAges 18 years+ - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Phoenix, ArizonaAges 18 years+ - NCT07629544RecruitingPhase 3
Testing DA-302168S for weight loss in overweight and obese adults
This study tests a new medication called DA-302168S to help people lose weight. You may qualify if you're overweight or obese and meet certain health requirements.
BeijingAges 18–75 - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+ - NCT07379970Recruiting
Wearable devices and coaching for adults with central obesity
This study tests whether wearing a fitness tracker and getting health coaching by phone or video can help adults with central obesity become more active and improve their heart health. It lasts for 6 months and is run by the University of Hong Kong.
Hong KongAges 40 years+
Hear when a new Overweight or Obese Adults trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 808 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.