Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07594093RecruitingPhase 1
A study of REGN20934 for adults with overweight or obesity
This trial tests a new medication, REGN20934, to see how safe it is and how it works in the body for adults who are overweight or have obesity. It may help if you are looking for new treatment options.
Glendale, CaliforniaAges 18–65 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT06742112Recruiting
Arm and Breathing Test for People Who Are Overweight
This study looks at how well people who are overweight or obese can use their arms and breathe while performing a 6-minute pegboard and ring test. Researchers want to see if this test can help measure physical function in this group.
KırşehirAges 18–65 - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT06996431Enrolling by invitation
Weight loss program with mobile health support
This study tests a new way to help adults lose weight using a smartphone app and health coaching. You might qualify if you are overweight, live in Hong Kong, speak Chinese, and can walk without help.
Hong KongAges 18 years+ - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Dothan, AlabamaAges 18–70 - NCT06868862Recruiting
Exercise and fat loss in young women with overweight or obesity
This study compares two types of exercise (short bursts of intense activity vs. moderate continuous activity) to see which is better for fat loss in young women who have overweight or obesity. The exercises have the same total energy used, so the results can show which type might be more helpful for weight management.
São Paulo, São PauloAges 20–45 - NCT06842186RecruitingPhase 1/Phase 2
Study of WVE-007 for overweight or obesity
This trial tests an experimental drug called WVE-007 for people who are overweight or have obesity. It aims to help with weight loss and is looking at both a group without diabetes and a group with prediabetes or type 2 diabetes.
Baltimore, MarylandAges 18–60 - NCT06636773Recruiting
Aerobic vs Aerobic Plus Yoga for Weight Loss
This study compares two exercise programs — aerobic exercise alone versus aerobic exercise combined with yoga — to see which helps adults with overweight or obesity lose weight. You would need to follow a diet plan and attend regular exercise sessions at the University of Kansas Medical Center.
Kansas City, KansasAges 18 years+ - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75 - NCT07638345Recruiting
AI-powered weight management for teens with diabetes or asthma
This study tests a smartphone app that uses artificial intelligence to help families manage weight and health for teenagers (ages 12–21) with Type 1 Diabetes or asthma. The app is designed to be personalized to each family's needs and may help improve overall health outcomes.
SevilleAges 18 years+ - NCT07183228Recruiting
Eatit weight-loss program for obesity
This trial tests a dietitian-led program called Eatit to help people with obesity lose weight and improve their eating habits. It's designed for adults who meet certain weight and health criteria.
Stockholm, Stockholm CountyAges 18 years+ - NCT07666425Recruiting
Understanding obesity types and treatment response
This study is following people with obesity to better understand different types of obesity and what affects treatment success. By joining, you help researchers learn which treatments work best for which people.
Bologna, BolognaAges 18 years+ - NCT07317115Recruiting
Comparing a new surgery to a diabetes drug for weight loss
This trial compares a new surgical procedure (duodeno-ileostomy) to a medication (semaglutide) for people with obesity and type 2 diabetes. It aims to see which approach works better for weight loss and blood sugar control.
Westmount, QuebecAges 18 years+ - NCT06604650Recruiting
Park-based health program for older adults in Miami
This study looks at how community park programs can help older adults stay healthy. It will use information already collected from people who are already part of the Miami-Dade Active Older Adults study.
Miami, FloridaAges 50–95 - NCT05713448Recruiting
Check how common overweight is in adults with type 1 diabetes
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
LeuvenAges Any age - NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT06626360Recruiting
Screening for malnutrition in people with obesity
This study looks at whether overweight or obese patients may also be malnourished. Researchers will screen people with a BMI of 25 or higher to find hidden malnutrition so they can get the right nutritional support.
AmsterdamAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.