Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07641361Recruiting
Staying Hydrated to Feel Better on GLP-1 Medication
This study tests whether drinking more water helps reduce uncomfortable side effects (like nausea and vomiting) when you first start taking GLP-1 medications for weight loss or diabetes. You'll be asked to follow a hydration plan and report how you feel.
Buffalo, New YorkAges 18–60 - NCT07582718Recruiting
High-Intensity Interval Training for Fitness in Adults
This study tests whether intense, short bursts of exercise can improve fitness in adults who are overweight. You'll do whole-body workouts designed to boost cardiovascular health and physical performance.
BrusselsAges 18–55 - NCT07575438RecruitingPhase 2
Fish oil types for reducing diabetes risk
This study tests whether different types of fish oil can improve blood sugar and cholesterol levels in people at high risk for type 2 diabetes. The goal is to see if one type of fish oil is better at reducing diabetes risk.
Montreal, QuebecAges 40–70 - NCT07511205RecruitingPhase 1
Study of AZD1043 for overweight or obesity
This trial tests a new medicine called AZD1043 in healthy adults who are overweight or have obesity. It aims to see if the medicine is safe and how the body handles it.
Glendale, CaliforniaAges 18–65 - NCT07504068Recruiting
Exercise and supplement for metabolic health in overweight adults
This trial tests whether a combination of physical exercise and a nutritional supplement can improve body composition, metabolism, and overall health in adults who are overweight and have early signs of metabolic problems. It may help you if you are looking for a non-drug approach to boost your health.
Valencia, ValenciaAges 50–65 - NCT07444736Enrolling by invitation
Exercise with blood flow restriction for adults with obesity
This study tests if adding blood flow restriction to resistance training can improve muscle strength and health in adults with obesity. It may help you build muscle more efficiently with lighter weights.
Tlajomulco de Zúñiga, JaliscoAges 18–30 - NCT07445503Recruiting
High phenolic olive oil for metabolic health in central obesity
This trial tests whether a special olive oil rich in natural plant compounds (polyphenols) can improve metabolic health in people with belly fat. You may be eligible if you are an adult with overweight or obesity and have at least one related health issue like high blood pressure, high blood sugar, or abnormal cholesterol.
KalamataAges 18–80 - NCT07396805Recruiting
Food is medicine study for obesity with food insecurity
This study tests whether providing healthy food and support can help adults with obesity and food insecurity lose weight. It looks at how food assistance programs might improve health.
Baltimore, MarylandAges 18 years+ - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07283406Enrolling by invitation
High-intensity interval training for young adults with obesity
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart health and fitness in young adults with obesity. You would participate in a supervised exercise program to see if it helps lower your risk of future health problems.
Guadalajara, JaliscoAges 18–35 - NCT07205432RecruitingPhase 1
Testing XTL6001 in healthy and obese adults
This early-stage trial tests a new medication (XTL6001) in healthy and obese adults to see if it is safe. It is for people who are not diabetic, have no history of certain stomach, pancreas, or gallbladder problems, and have a BMI up to 40.
Beijing, Beijing MunicipalityAges 18–65 - NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT06893016RecruitingPhase 3
Study of RAY1225 for adults with obesity or overweight
This trial tests a new medicine called RAY1225 to help people lose weight. If you have obesity or are overweight with related health conditions, you may be able to join.
BeijingAges 18 years+ - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT00428987Recruiting
Study of body and behavior traits in weight groups
This study looks at how physical traits and everyday behaviors differ among people who are overweight, obese, or in the normal-weight range. It may help researchers better understand risk factors related to weight and health.
Bethesda, MarylandAges 18–100 - NCT07837973RecruitingPhase 2
Medicine to maintain weight loss after weight-loss shots
This study tests a new medicine called ALV-100 to see if it can help people who have already lost weight with a weight-loss injection or pill keep the weight off. You must be currently on a stable weight-loss medicine and have lost at least 10% of your body weight to join.
Birmingham, AlabamaAges 18–75 - NCT07855939Recruiting
Iron absorption and loss in women over time
This study looks at how well women absorb iron and lose it over a long period. It compares normal-weight women with overweight or obese women who have low-level inflammation. The goal is to understand iron levels in the body, which could help improve iron recommendations.
Nakhon PathomAges 40–50 - NCT07789106Recruiting
CoQ10 for fatigue and strength in GLP-1 users
This study tests whether Coenzyme Q10 (CoQ10) can help reduce fatigue and improve muscle strength in people who are taking GLP-1 medications for weight management. You will be asked to take a daily supplement (CoQ10 or placebo) for a period and track your progress via a smartphone app.
GlasgowAges 30–65 - NCT07778524RecruitingPhase 1
Alpelisib challenge test for body weight study
This study tests a single dose of a drug called alpelisib to see how it affects body weight and metabolism. It may help researchers understand how the drug could be used for weight-related conditions.
New York, New YorkAges 18–70 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Birmingham, AlabamaAges 18 years+ - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07717658Recruiting
Family weight wellness program for teens and parents
This study tests a weight wellness program that uses food support and group medical visits for teens and their parents. It aims to help families adopt healthier habits together over 12 months.
Boston, MassachusettsAges 12–17 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.