Clinical trials
Overweight clinical trials
Below are recruiting overweight clinical trials, each written for real people, not researchers. We’re tracking 532 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT06067906Recruiting
Weight loss diet after pre-eclampsia in overweight women
This trial tests whether a special diet (either a low-calorie or a 'dissociated' diet) helps women who have had pre-eclampsia lose weight. It may help you reduce future health risks.
Le MansAges 18–45 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07747857RecruitingPhase 1
Study of TQF3250 capsules for type 2 diabetes with overweight or obesity
This study tests a new capsule medicine for adults with type 2 diabetes who are overweight or have obesity. The goal is to see if it helps control blood sugar and weight.
Fuzhou, FujianAges 18–70 - NCT07745504RecruitingPhase 3
Comparing two versions of a new weight-loss medication
This study compares two different versions of an investigational weight-loss medication (cagrilintide) against a placebo to see which is more effective and safe for people with excess weight. Participation involves receiving injections and regular check-ins to monitor your progress.
Conyers, GeorgiaAges 18 years+ - NCT07743567Recruiting
Weight and pregnancy outcomes after GLP-1 use
This study looks at how a type of weight-loss medication called GLP-1 affects pregnancy and baby outcomes. It aims to learn if this medication is safe to use early in pregnancy.
Kansas City, KansasAges 18–45 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07738029Recruiting
Intensive lifestyle treatment for children with obesity and their families
This trial studies a 1-year intensive lifestyle program for children ages 10-16 with a high body mass index (ISO-BMI ≥30) and their families. It aims to help children who have struggled to lose weight with lifestyle changes alone.
Tampere, PirkanmaaAges 10–16 - NCT07740291Recruiting
Tirzepatide and lifestyle study for weight loss
This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.
Lubbock, TexasAges 18 years+ - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Anniston, AlabamaAges 18 years+ - NCT07717658Recruiting
Family weight wellness program for teens and parents
This study tests a weight wellness program that uses food support and group medical visits for teens and their parents. It aims to help families adopt healthier habits together over 12 months.
Boston, MassachusettsAges 12–17 - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07710729RecruitingPhase 1
How UBT251 Affects Birth Control and Stomach Emptying
This study tests a new medicine, UBT251, to see if it affects how birth control pills work and how quickly food leaves the stomach. It is for women with overweight or obesity who cannot get pregnant.
Montreal, QuebecAges 18–65 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT07708064Recruiting
Preventing weight regain with a smartphone program
This study tests a smartphone-based program to help people who have lost weight keep it off or lose more. It uses personalized tips and check-ins to prevent giving up if you regain some weight.
Springfield, OregonAges 18–70 - NCT07699445RecruitingPhase 4
Lumateperone for weight and mood in bipolar depression
This study tests if lumateperone, a medication for bipolar depression, can also help with weight and aging in people with obesity. You may qualify if you have bipolar I depression and a body mass index (BMI) over 30.
Boston, MassachusettsAges 18–65 - NCT07702461Recruiting
Resistance training survey for people on weight loss meds
This trial is an online survey to understand how people taking GLP-1 medications (like Ozempic or Wegovy) are doing with resistance training. If you're an adult on a stable dose of a GLP-1 med for weight or diabetes, your input can help shape better exercise advice.
Columbus, OhioAges 18 years+ - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT07703371Recruiting
Kodo millet porridge and its effect on gut health and metabolic syndrome
This study tests whether eating Kodo millet porridge every day for 12 weeks can improve gut health and reduce risk factors for metabolic syndrome (like being overweight). If you are between 20 and 60 years old, are overweight or obese, and are willing to eat the porridge daily without changing your diet or exercise, you may be able to join.
Mysore, KarnatakaAges 20–60 - NCT07698145Recruiting
How weight-loss medications affect body muscle, with and without exercise
This study looks at what happens to your body (especially muscle) when you take a newer weight-loss medication, either with or without adding an exercise program. It could help you understand how to best protect your muscle while losing weight.
Kansas City, KansasAges 18–64
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Common questions
- Are there clinical trials for overweight?
- Yes. Clin2 currently lists 532 recruiting overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.