Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT06987175Recruiting
Sedante Neo therapy for low back pain
This study tests a therapy called Sedante Neo to see if it reduces pain, improves movement, and boosts quality of life in people with common low back pain. It is designed for adults aged 20–40 whose back pain is mild to moderate and affects daily life.
Lahore, Punjab ProvinceAges 5 months–9 months - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06889389Recruiting
Education and exercise for neck pain relief
This study tests if combining education with exercise can reduce pain and improve function for people with non-specific neck pain (pain not caused by a specific injury or disease). Participants will learn about their condition and do guided exercises.
Elche, AlicanteAges 18–65 - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06076889Recruiting
Online pain relief program for Canadian youth with chronic pain
This trial tests a virtual program called Power Over Pain Portal, designed to help Canadian youth with chronic pain manage their symptoms from home. It offers step-by-step support through a smartphone or computer over two months.
Toronto, OntarioAges 12–18 - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT06206148Recruiting
Comparing ways to record pain after surgery
This study compares different methods of recording pain after surgery to see which is easiest and most accurate. If you have surgery and can use a smartphone or a button, you may be able to help.
San Francisco, CaliforniaAges 18 years+ - NCT06818175Recruiting
Study of back muscle tissue and treatment for low back pain
This study looks at the tissue in your lower back using ultrasound and physical exams. It tests a treatment to see if it helps people with new or long-term low back pain, and also compares results to people without pain.
Blacksburg, VirginiaAges 18–50 - NCT06785909Recruiting
Understanding why pregnancy back and pelvic pain persists
This study looks at why some women develop ongoing pain in the lower back or pelvis during pregnancy. It tests how your body's sense of movement, fear of pain, and inflammation might be related. You may join if you are early in a single pregnancy and do not have that pain yet.
HasseltAges 18–40 - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06778070Recruiting
Pelvic pain study testing yoga therapy for relief
This trial tests whether yoga therapy can help reduce chronic pelvic pain in women and non-binary individuals over 6 months. You'll join online yoga classes and see if they improve your pain and daily life.
San Francisco, CaliforniaAges 18 years+ - NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT06350786Recruiting
Using a placebo to help reduce opioid pain medication
This trial tests whether a special placebo pill, given with your knowledge, can help you reduce your opioid pain medication. You'll work with your own doctor to safely lower your dose while taking the placebo.
Zurich, Canton of ZurichAges 18 years+ - NCT06224829Recruiting
Massage therapy for long-term neck pain
This study tests whether massage can help people with neck pain that has lasted at least 3 months. You will receive massage sessions, and researchers will track how your pain changes.
Gainesville, FloridaAges 18–60 - NCT06212349Recruiting
Physiotherapy for pain and quality of life in endometriosis
This trial tests a combined therapy and education program for women with endometriosis. It aims to reduce pelvic pain, improve muscle function, and enhance quality of life. If you have persistent pelvic pain and certain muscle issues, this study may help.
ValenciaAges 18–45 - NCT06123715RecruitingPhase 2
Vitamin C to reduce pain after knee replacement
This study tests whether taking vitamin C before and after knee replacement surgery can reduce long-term pain. You may be eligible if you are having knee replacement for osteoarthritis and are generally healthy.
Toronto, OntarioAges 18 years+ - NCT06058624Recruiting
Digital pain management program for veterans
This study tests a new digital program that helps veterans with long-term pain learn to accept and cope with it. You would use a computer at home to complete the program and share your feedback.
West Haven, ConnecticutAges 18 years+ - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT05920382Recruiting
Radiofrequency treatment for long-term knee pain after knee surgery
This trial studies whether a radiofrequency procedure can reduce chronic knee pain after knee replacement surgery. It may help people who still have bothersome pain between 6 months and 5 years after their operation, as long as their pain pattern and medications are stable.
Barcelona, CataloniaAges 18 years+ - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.