Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT07416448Recruiting
Pain treatment for nerve-related pain after combat injury
This study tests a procedure to treat pain from nerve damage (neuroma) after a combat injury. It aims to help people with moderate to severe pain that comes from a specific nerve.
RivneAges 18 years+ - NCT07436806Recruiting
Comparing nerve blocks for pain after chest surgery
This trial compares two types of nerve blocks to see which one better prevents long-term pain after video-assisted chest surgery. It may help find a way to reduce chronic pain after your procedure.
Istanbul, BagcilarAges 18–75 - NCT07491549Recruiting
Pain education group therapy for chronic pain
This trial tests if group education about pain can help people with chronic pain move more, feel better, and have less fear of movement. It's looking for adults whose pain has lasted more than 3 months and affects their daily life.
Tartu, TartuAges 16–65 - NCT07493226Recruiting
NSAIDs for Frozen Shoulder Pain Study
This study tests different types of nonsteroidal anti-inflammatory drugs (NSAIDs) to see which works best for people with frozen shoulder. It may help you if you have ongoing shoulder pain and stiffness without other shoulder injuries.
Konya, SelçukluAges 18–75 - NCT07498491Recruiting
Weighted blanket study for adults with ongoing pain
This study tests whether using a weighted blanket (10–25 pounds) while sleeping can help adults with chronic pain. If you join, you'll use the blanket every night for about 5 weeks and complete simple online questionnaires.
Portland, OregonAges 18 years+ - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07604376Recruiting
Nerve Block Pain Relief After Cesarean Delivery
This study tests whether a nerve-numbing injection in the abdomen helps reduce pain after a cesarean (C-section) delivery. The injection uses a local anesthetic to numb the area around your surgical wound, potentially reducing pain and the need for stronger pain medicines after surgery.
Târgu Mureş, Mureș CountyAges 18 years+ - NCT07642674Recruiting
IV Pain Relief After Shoulder Arthroscopy Surgery
This study tests whether an intravenous pain medication (dexketoprofen) given during shoulder arthroscopy can reduce pain that returns after surgery ends. Researchers want to see if this approach helps keep patients more comfortable and need fewer pain medications overall.
Eskişehir, OdunpazarıAges 18–70 - NCT07568405Enrolling by invitation
How Remifentanil Affects Pain Sensitivity During Surgery
This study tests how a pain-relief medication called remifentanil changes the way your body responds to pressure pain. Researchers will measure your pain sensitivity before and after receiving this medication to better understand how it works.
Brussels, Brussels CapitalAges 18–65 - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT07306312Enrolling by invitation
How thoughts affect low back pain with manual therapy
This study looks at how your thoughts and feelings about your chronic low back pain affect your pain and ability to move, during a course of manual therapy (hands-on treatment by a therapist). It may help you understand if your mindset influences your recovery.
AthensAges 18–65 - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT07244861Enrolling by invitation
TENS for neck muscle stiffness and pain
This study tests whether a gentle electrical stimulation device (TENS) applied to the neck can reduce muscle stiffness and pain in people with ongoing neck pain. If you have had neck pain for at least 6 weeks and are willing to avoid certain medications the day before, you may be able to join.
ErzurumAges 18–50 - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT05315596Enrolling by invitation
Tracking pain and recovery answers after surgery
This study checks how patients report pain and recovery over time after surgery. It may help improve how hospitals understand and manage pain after operations.
JenaAges 18 years+ - NCT06870162Recruiting
Pain disengagement training: a writing study for chronic pain
This study tests a writing-based program to help people with chronic pain learn to disengage from pain-related thoughts. It aims to reduce pain catastrophizing and improve daily function.
Boston, MassachusettsAges 18 years+ - NCT07641517RecruitingPhase 2
Testing LY4065967 for chronic knee osteoarthritis pain
This study tests an experimental drug called LY4065967 to see if it can help reduce pain from osteoarthritis in the knee. You'll be in the trial for several months, with regular check-ins and pain assessments.
Birmingham, AlabamaAges 40 years+ - NCT07489625RecruitingEarly Phase 1
Electroacupuncture and ear acupressure for cancer pain
This study tests whether adding electroacupuncture (a treatment using mild electric pulses on needles) and ear acupressure (pressing on specific points on the ear) to the pain medicine hydromorphone helps reduce cancer-related pain that isn't well managed by usual treatments.
XiningAges 18–80 - NCT06617494Recruiting
Study of pain control in chronic jaw pain
This study looks at how well the body's natural pain control system works in people with long-term jaw pain (TMD). It compares people with and without jaw pain to better understand why some have trouble turning off pain signals.
Minneapolis, MinnesotaAges 18–74 - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT04556890Recruiting
Brain stimulation for treatment-resistant depression and chronic pain
This study tests a non-invasive brain stimulation treatment, called transcranial magnetic stimulation (TMS), to see if it can help people who have both major depression that hasn't improved with medication and chronic pain from fibromyalgia or chronic fatigue syndrome. It aims to reduce both depression and pain symptoms.
Los Angeles, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.