Clinical trials
Parkinson s Disease clinical trials
Below are recruiting parkinson s disease clinical trials, each written for real people, not researchers. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05656586Recruiting
At-home testing for Parkinson’s patients with a DBS device
This study checks how well people can do specific at-home movement tasks using their Medtronic Percept deep brain stimulation (DBS) system. It may help improve how DBS settings are tested and monitored outside the clinic, which could make care safer and more personalized.
Minneapolis, MinnesotaAges Any age - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05489575Recruiting
CPAP machine for high blood pressure when lying down at night
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Nashville, TennesseeAges 40–80 - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05266872Recruiting
Earlier diagnosis and better treatment study for Parkinson’s
This study is looking to improve how Parkinson’s and related brain conditions are identified and treated sooner. You may be asked to share your health information and provide blood or other samples, and possibly have procedures like a spinal fluid test or a small skin sample.
LuxembourgAges 18 years+ - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT04957095Recruiting
Testing brain wiring signals during planned deep brain stimulation
This study looks at how brain networks work during a procedure used to treat movement symptoms in Parkinson’s disease. It may help researchers better understand the brain signals involved, which could improve future deep brain stimulation planning.
Dallas, TexasAges 18–89 - NCT04876339Recruiting
Sound-based training to improve walking after brain illness
This study tests whether using special sounds (sonification) during gait training can improve walking for people with stroke, Parkinson’s disease, or multiple sclerosis. It may help your walking speed, stamina (fatigue), and overall walking pattern.
PaviaAges Up to 80 years - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Tucson, ArizonaAges Any age - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04286308Recruiting
Testing brain-speech recordings during DBS for movement disorders
This study looks at how brain and speech networks work while people with Parkinson’s disease, essential tremor, or dystonia are getting deep brain stimulation (DBS). It may help doctors better understand and possibly improve speech outcomes for people receiving DBS.
Boston, MassachusettsAges 18–85 - NCT04246437RecruitingPhase 1
Brain imaging study for autonomic failure with possible Parkinson disease
This Phase 1 study uses a special injected imaging tracer and an MRI scan to look at brain function in people with autonomic failure. It may help researchers understand what’s happening in conditions that can be related to Parkinson disease, multiple system atrophy, or dementia with Lewy bodies.
Nashville, TennesseeAges 18 years+ - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT03664609Recruiting
Study of outcomes for people with deep brain stimulation
This study looks back at results for people who have already had deep brain stimulation (DBS) or could get it. It aims to understand how DBS is used and what outcomes people experience.
Phoenix, ArizonaAges Any age - NCT03217110Recruiting
Brain stimulation study for thinking and control
This trial tests whether stimulating the cerebellum (a part of the brain involved in coordination and learning) can improve “cognitive control,” or the ability to focus and manage thoughts. You may be able to join if you have a diagnosis they are specifically enrolling for and you can safely complete the stimulation and study procedures.
Iowa City, IowaAges 18–90 - NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT01734122Recruiting
Focused radiation for essential or Parkinson tremor
This trial tests whether precisely targeted radiation to the brain can reduce tremors in people whose symptoms are not controlled enough by medication. It may help those who prefer radiation over deep brain surgery options.
Nashville, TennesseeAges 18 years+ - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT05370079Recruiting
Control group for people with specific serious illnesses
This trial includes a “control” group of people with certain diseases to compare outcomes against another group. If you qualify, you may receive the standard approach used in usual care rather than the experimental treatment.
BronAges 18 years+
Hear when a new Parkinson s Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for parkinson s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.