Clinical trials
Paroxysmal Atrial Fibrillation clinical trials
Below are recruiting paroxysmal atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07454317Recruiting
Biofeedback for managing paroxysmal atrial fibrillation
This trial tests whether biofeedback—a technique that helps you learn to control your body's stress responses—can help people with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) manage their condition better. If you have this kind of AFib and are otherwise stable, this study may be a good fit.
Liverpool, MerseysideAges 18 years+ - NCT07447297Recruiting
Early Rhythm Control for Device-Detected Fast Heart Episodes
This trial tests whether starting treatment early to control your heart's rhythm can help people with a heart device who have short bursts of a fast heartbeat (called atrial high rate episodes) but haven't yet been diagnosed with atrial fibrillation on a standard EKG or Holter monitor.
Seoul, SeoulAges 19 years+ - NCT07444320Recruiting
Testing new energy pulses for atrial fibrillation treatment
This trial tests a new way to deliver energy (FARAPULSE PFA system) to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if these new waveforms can safely and effectively stop AF symptoms and improve quality of life.
SplitAges 18 years+ - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07424326Recruiting
Extended ablation vs. standard treatment for persistent atrial fibrillation
This trial compares two catheter ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own). It will test whether a more extensive ablation (burning more heart tissue) works better than the standard procedure of isolating the pulmonary veins (the veins that bring blood from the lungs to the heart). If you have this condition and have had at least one episode in the past year, this study might help you find a more effective treatment.
OlomoucAges 18–80 - NCT07424690Recruiting
Comparing ablation with medication care for older adults with atrial fibrillation
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
LinköpingAges 78 years+ - NCT05908955Recruiting
Atrial fibrillation ablation with extra vein targeting
This trial studies a modified ablation procedure that targets the superior vena cava in addition to the pulmonary veins to help stop episodes of paroxysmal (coming and going) atrial fibrillation. It may help people whose symptoms continue despite antiarrhythmic medicines.
Beijing, Beijing MunicipalityAges 40–75 - NCT07344961Recruiting
Micra AV2 study: tracking heart rhythm and AFib
This study looks at how well the Micra AV2 pacemaker tracks your heart’s natural rhythm and detects brief episodes of atrial fibrillation (a fast, irregular heartbeat). It is for people who already have or will get this pacemaker and have had AFib that comes and goes.
New Hyde Park, New YorkAges 18 years+ - NCT07321964Recruiting
Digital yoga for quality of life with atrial fibrillation
This trial tests if a digital yoga program can improve quality of life, blood pressure, and heart rate in people with atrial fibrillation. It offers a convenient way to practice yoga from home using a smartphone or tablet.
HerlevAges Any age - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Birmingham, AlabamaAges 18 years+ - NCT07281898Recruiting
Burst stimulation for paroxysmal atrial fibrillation
This trial tests a special type of pacing called burst stimulation to see if it can help people with paroxysmal atrial fibrillation (AF) who are already scheduled for their first catheter ablation. The goal is to improve outcomes and reduce AF episodes.
Wuhan, HubeiAges 18–80 - NCT07267949RecruitingPhase 2
Study of AP31969 for atrial fibrillation rhythm control
This study tests a new medication, AP31969, to control heart rhythm in people with atrial fibrillation. It compares the drug to a placebo to see if it can reduce how often AF episodes happen over time.
Plovdiv, PDAges 18 years+ - NCT05565781Recruiting
Watch for hidden atrial fibrillation after unexplained stroke
This study uses a smartwatch and a longer heart-monitoring test (a Holter) to find an irregular heart rhythm called atrial fibrillation after a stroke whose cause is unclear. If they detect it, it may help guide better prevention and treatment to reduce future stroke risk.
Barcelona, CataloniaAges 55 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT07181590Recruiting
Balloon-based ablation for atrial fibrillation: post-approval study
This trial tests a balloon catheter that uses pulsed field energy to treat atrial fibrillation (AF) in people who have tried medication without success. It aims to see how well it works in real-world use.
LinzAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07156877Recruiting
Balloon Catheter Ablation for Atrial Fibrillation
This study tests a new balloon catheter that uses pulsed electric fields to isolate the veins that carry blood from your lungs to your heart. It may be a treatment option for people with atrial fibrillation who are scheduled for an ablation procedure.
BrugesAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07100483Enrolling by invitation
Comparing surgery methods for atrial fibrillation
This trial studies different surgical techniques for treating atrial fibrillation during heart surgery. It may help people with a history of AFib who are already scheduled for open-heart surgery.
Grand Rapids, MichiganAges 18–85 - NCT02741349Recruiting
Checking stroke and bleeding risks in atrial fibrillation
This study looks at how to better predict both stroke risk and bleeding risk in people with atrial fibrillation. It may help doctors choose safer blood-thinner treatment and follow-up plans.
ParisAges 18 years+ - NCT07018596Recruiting
New pulsed field ablation for paroxysmal atrial fibrillation
This trial tests a new type of heart procedure that uses gentle electrical pulses to fix abnormal signals in the upper chambers of the heart for people with a specific type of atrial fibrillation that comes and goes on its own. It may be an option if your AFib episodes stop within 7 days and medications haven't helped enough.
Prague, RoentgenovaAges 18–85
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Common questions
- Are there clinical trials for paroxysmal atrial fibrillation?
- Yes. Clin2 currently lists 179 recruiting paroxysmal atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a paroxysmal atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a paroxysmal atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.