Clinical trials
Paroxysmal Atrial Fibrillation clinical trials
Below are recruiting paroxysmal atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT06719921Enrolling by invitation
Catheter ablation for atrial fibrillation without x-ray
This study tests a way to perform catheter ablation for atrial fibrillation using a non-fluoroscopic lab, meaning no x-ray is needed during the procedure. It may help patients avoid radiation exposure.
Hangzhou, ZhejiangAges 18 years+ - NCT06801392Recruiting
Pulsed-field ablation for non-paroxysmal atrial fibrillation
This trial tests a new way to treat non-paroxysmal atrial fibrillation (AF) using a focused type of ablation (pulsed-field energy) on specific areas of the heart. It aims to see if targeting the left atrial wall and mitral isthmus can improve outcomes for people who have not had this procedure before.
PragueAges 18 years+ - NCT04240366Recruiting
Extra left atrial appendage treatment during AF ablation
This trial tests whether adding treatment to the left atrial appendage during a standard catheter ablation helps people with persistent atrial fibrillation (AF). It may improve how well AF is controlled, but you must meet specific heart rhythm and heart scan measurements to join.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT06798714RecruitingPhase 4
Colchicine to prevent irregular heartbeat after heart surgery
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
TomskAges 18 years+ - NCT07430007Recruiting
Exercise and diet to reduce AFib burden
This study tests whether a program of exercise and healthy eating changes can reduce how often atrial fibrillation (AFib) happens and help you lose weight. It may be a good fit if you are overweight, have AFib, and are ready to make lifestyle changes.
Jyväskylä, Central FinlandAges 18–75 - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT05341986Enrolling by invitation
ED tool to help prevent stroke in atrial fibrillation
This study tests an electronic decision-support tool used in the emergency department (ED) to help clinicians choose the safest way to prevent stroke when atrial fibrillation is newly found. It may help by improving how quickly and consistently stroke-prevention treatment is considered.
Portland, OregonAges 18 years+ - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT07508618RecruitingPhase 4
Qidong Yixin Granule for preventing atrial fibrillation after ablation
This trial tests whether a traditional Chinese medicine granule, Qidong Yixin, can help prevent atrial fibrillation from coming back after a heart ablation procedure. It is for people with persistent atrial fibrillation who have not had good results from other heart rhythm medications.
HangzhouAges 18–80 - NCT06099730Recruiting
Pulsed field ablation for atrial fibrillation
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
Jonesboro, ArkansasAges 18–80 - NCT06067438RecruitingPhase 2
Amiodarone to Prevent Irregular Heartbeat After Esophageal Cancer Surgery
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
Portland, OregonAges 18 years+ - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT06005233Recruiting
Smartwatch heart monitoring after unexplained stroke
This trial uses a smartwatch to look for hidden atrial fibrillation (an irregular heart rhythm) in people who have had a stroke or TIA with no known cause. It could help find the reason for the stroke and guide treatment to prevent another one.
MunichAges 40 years+ - NCT07621055Recruiting
AI software to guide heart rhythm ablation treatment
This study tests new AI software (Volta AF-Xplorer II) that helps doctors guide catheter ablation—a procedure to treat irregular heartbeats like atrial fibrillation. The software may help doctors perform the procedure more effectively and safely in real-world settings.
MarseilleAges 18 years+ - NCT05539040Recruiting
Testing why certain heart signals trigger atrial fibrillation
This trial studies abnormal electrical signals in the right upper heart chamber and how they relate to atrial fibrillation (AF). It may help improve how doctors target AF treatment during catheter ablation for people who have AF symptoms.
LondonAges 18–85 - NCT07617974Recruiting
Heart valve changes in atrial fibrillation patients
This study looks at how atrial fibrillation (a common heart rhythm problem) affects the tricuspid valve—one of your heart's four valves. Researchers will use special ultrasound imaging to understand these changes and help improve future treatment.
Milan, MilanAges 18 years+ - NCT04298723Recruiting
Left atrial appendage closure vs blood thinners after brain bleed
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
Mannheim, Baden-WurttembergAges 18 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07353775Recruiting
Heart procedure using imaging and pulsed energy
This trial uses a special imaging tool inside the heart to guide a new type of energy (pulsed field) to treat a specific area in the heart that can cause atrial fibrillation (an irregular heartbeat). It may help people with paroxysmal or persistent atrial fibrillation who need a procedure called CTI ablation.
BeijingAges 18 years+ - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+
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Common questions
- Are there clinical trials for paroxysmal atrial fibrillation?
- Yes. Clin2 currently lists 181 recruiting paroxysmal atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a paroxysmal atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a paroxysmal atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.