Clinical trials
Pediatric Kidney Disease clinical trials
Below are recruiting pediatric kidney disease clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06430684RecruitingEarly Phase 1
SGLT2 inhibitor trial for children with kidney disease
This trial tests a medication called SGLT2 inhibitor (a type of diabetes drug that may also help protect the kidneys) in children with chronic kidney disease. It aims to see if the drug is safe and easy to use in children ages 2–18 with moderate to severe kidney problems.
Chicago, IllinoisAges 12–25 - NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Alabaster, AlabamaAges 10–65 - NCT03619850RecruitingPhase 3
Ferumoxytol vs iron sucrose for child kidney anemia
This study compares two IV iron treatments—ferumoxytol and iron sucrose—to treat iron deficiency anemia in children with chronic kidney disease. It aims to see which option works better and is safe, and also to learn how each medicine behaves in the body.
Hollywood, FloridaAges 2–17 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT06860711RecruitingPhase 4
NSAID safety in children with kidney disease having surgery
This study tests if a short course of NSAID pain relievers is safe for children with mild to moderate kidney disease who are having urologic surgery requiring an overnight hospital stay. The goal is to find better ways to manage pain after surgery in these patients.
Aurora, ColoradoAges 1.5 years–25 years - NCT06890143RecruitingPhase 3
Dapagliflozin for kids with genetic kidney disease and protein in urine
This trial tests if dapagliflozin, a medication that lowers blood sugar and protects the kidneys, can reduce protein in the urine of children with inherited kidney disease. It may help preserve kidney function when added to standard blood pressure medication.
Shanghai, Shanghai MunicipalityAges 6–18 - NCT02378805Recruiting
Alport syndrome registry to help delay kidney failure
This is a registry that collects information from people with Alport syndrome to better understand the disease and how to delay kidney failure. It may help researchers learn which factors and treatments are most important over time.
Göttingen, Lower SaxonyAges Any age - NCT07670988Recruiting
Kidney health in kids with inflammatory bowel disease
This study checks if children with inflammatory bowel disease (IBD) are more likely to have kidney problems. Researchers will look at medical records to compare kidney health in kids with IBD and those without.
Alessandria, PiedmontAges 2–17 - NCT06286098Enrolling by invitationPhase 3
Alpha lipoic acid for kids on dialysis
This trial tests if alpha lipoic acid, a common supplement, can help reduce stress on the body for children who are on regular hemodialysis. It may offer a way to support their health during treatment.
Cairo, El WeiliAges 8–16 - NCT03633708RecruitingPhase 3
Etelcalcetide for children with dialysis-related overactive parathyroid hormone
This trial studies etelcalcetide in children who have chronic kidney disease and too much parathyroid hormone while on hemodialysis. It aims to safely lower the hormone levels and help manage related bone/mineral problems.
Los Angeles, CaliforniaAges birth–18 years - NCT03959163Recruiting
Quick kidney MRI test in children with kidney infection
This study checks whether a fast kidney MRI (“Quick MRI”) can help doctors in children who are being evaluated for kidney infection (pyelonephritis). It may help confirm kidney involvement without relying only on slower or more complex tests.
Madison, WisconsinAges birth–21 years - NCT06300788Recruiting
Pyrophosphate study in children with kidney disease
This study looks at a natural chemical in the body called pyrophosphate (PPi) in children with chronic kidney disease. It aims to understand how kidney problems affect this chemical, which is important for bone health. The study needs kids with different kidney stages, including those on dialysis, with a transplant, or even healthy kids having surgery for comparison.
Nice, Alpes-MaritimesAges birth–18 years - NCT07568509RecruitingEarly Phase 1
Oxytocin levels in children with pituitary disease
This study measures oxytocin (a natural hormone) levels in children who have pituitary gland problems. Researchers want to understand if children with certain pituitary conditions don't make enough oxytocin, which could help guide future treatments.
Boston, MassachusettsAges 7–21 - NCT06601829Recruiting
Liver and kidney disease study in children
This study looks at children with congenital hepatic fibrosis and autosomal recessive polycystic kidney disease. It aims to learn more about these conditions and how they affect children.
SohagAges Any age - NCT07369063RecruitingPhase 2
Vitamin D for pediatric Graves' disease
This study tests whether adding vitamin D therapy to the usual Graves' disease treatment (methimazole) can improve thyroid function and lower antibody levels in children. If your child is between 9 and 17 and recently diagnosed, they may be able to participate.
New Hyde Park, New YorkAges 9–17 - NCT06728228Recruiting
Amnioinfusion for fetal kidney failure
This trial is testing whether adding fluid back into the womb (amnioinfusion) can help babies whose kidneys are not working and who have no amniotic fluid early in pregnancy. It may improve the baby's chances of survival and lung development.
Dallas, TexasAges Any age - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT03541785Enrolling by invitation
Using NGAL to guide fluids and start kidney-filtering in children
This study tests whether measuring a urine protein called NGAL can help doctors choose the right fluid amount and decide when to start a kidney-filtering treatment called CRRT in critically ill children with kidney injury. If it works, it may help treat kidney problems sooner and more safely.
Cincinnati, OhioAges 3 months–25 years - NCT06641843Enrolling by invitation
Heart stress test using MRI for children with heart disease
This study uses magnetic resonance imaging (MRI) to look at blood flow to the heart muscle during stress in children with certain heart conditions. It may help doctors better understand how the heart is working.
Chengdu, SichuanAges Up to 18 years - NCT07398508RecruitingPhase 1/Phase 2
Northera for dizziness and diarrhea in Menkes disease survivors
This trial tests if the drug Northera (droxidopa) can help children with Menkes disease who have dizziness when standing or chronic diarrhea. It aims to improve these symptoms by supporting blood pressure and bowel function.
New York, New YorkAges 7–17 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Aurora, ColoradoAges 8–45 - NCT07184450RecruitingPhase 1
CAR-T cell therapy for children with hard-to-treat rheumatic diseases
This trial tests a new treatment using your child's own immune cells, modified to target B cells and fight severe rheumatic diseases like juvenile dermatomyositis, arthritis, scleroderma, or Sjogren's syndrome. It's for children who haven't improved with standard treatments.
Hangzhou, ZhejiangAges 5 years+ - NCT01893710Recruiting
Collecting children and adult belly fluid and tissue for kidney care research
This study collects samples from the belly (related to the peritoneal lining) to build a “biobank” for future research. It may help patients and families by improving understanding of kidney disease and kidney dialysis-related health issues.
Birmingham, AlabamaAges 1 day–90 years - NCT05003986RecruitingPhase 2
Sparsentan for children with protein leaking kidney diseases
This Phase 2 study tests sparsentan in children with certain kidney diseases that cause high amounts of protein in the urine. It aims to see if the medicine can reduce kidney damage signals and protein leakage compared with standard care.
Los Angeles, CaliforniaAges 1–17
Hear when a new Pediatric Kidney Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pediatric kidney disease?
- Yes. Clin2 currently lists 32 recruiting pediatric kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.