Clinical trials
Pharmacokinetics and Pharmacodynamics clinical trials
Below are recruiting pharmacokinetics and pharmacodynamics clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT07142707RecruitingPhase 1
Testing a new obesity drug for safety and effects
This study tests an investigational medication called MBX 4291 for adults with obesity. It aims to see if the drug is safe and how it works in the body, which could lead to a new weight-loss treatment option.
Doral, FloridaAges 18–65 - NCT07118085RecruitingPhase 1
Testing the safety of IMC-003 in healthy postmenopausal women
This study tests the safety of a new medicine called IMC-003. It is for healthy women who have gone through menopause. You may be able to join if you are between 45 and 75 years old and meet certain health criteria.
Chengdu, SichuanAges 45–75 - NCT07085507RecruitingPhase 1/Phase 2
Testing a new drug for multiple sclerosis in healthy people and MS patients
This trial tests an experimental oral drug called VT7208 in both healthy volunteers and people with multiple sclerosis (MS). The goal is to see if it is safe and how the body processes it, which could lead to a new treatment option for MS.
Adelaide, South AustraliaAges 18–65 - NCT07051629RecruitingPhase 1
Testing a new epilepsy medicine for safety in healthy people and patients
This study tests a new medicine called SIF001 for safety. It first gives the medicine to healthy volunteers, and then to people with epilepsy who have seizures even while on their current medicines. The goal is to find a safe dose.
Tucson, ArizonaAges 18–70 - NCT07051603RecruitingPhase 1
Safety study of SAL0140 in healthy Chinese adults
This study tests the safety and how the body handles a new medicine (SAL0140) in healthy people. It helps doctors find the right dose and check for side effects.
Guangzhou, GuangdongAges 18–65 - NCT07040930RecruitingPhase 1
Testing the safety of GenSci120 in healthy adults
This study tests a new drug called GenSci120, given as multiple injections under the skin, to see if it is safe in healthy adults. It will also measure how the drug moves through the body and how it affects certain immune markers.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Glendale, CaliforniaAges 18–75 - NCT07032688RecruitingPhase 1
Study of SHR-3167 for type 2 diabetes
This trial tests an experimental drug called SHR-3167 in people with type 2 diabetes. The goal is to see how the drug works in the body and how it affects blood sugar. It may be an option for adults who have had diabetes for at least 6 months.
Chengdu, SichuanAges 18–59 - NCT06993636Recruiting
Study of rivaroxaban in Chinese children with large heart artery bulges
This trial is testing the drug rivaroxaban in children aged 2 to 17 who have large bulges (aneurysms) in their heart arteries after Kawasaki disease. It aims to see how the drug works in the body to prevent blood clots.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT07005713RecruitingPhase 1
Study of tacabrutideg for chronic spontaneous urticaria
This trial tests a new oral medication called tacabrutideg (BGB-16673) for chronic spontaneous urticaria, a condition with frequent hives and itching. It aims to see how safe it is and how well it works, possibly offering a new option for people who still have symptoms despite antihistamines.
Beijing, Beijing MunicipalityAges 18–70 - NCT06980428RecruitingPhase 1
Safety study of AZD4954 in people with or without high Lp(a)
This trial tests a new drug called AZD4954 for safety. It includes healthy volunteers and people with high Lp(a) or dyslipidemia. The goal is to see if the drug is safe and how the body processes it.
Glendale, CaliforniaAges 18–70 - NCT06934408RecruitingPhase 1
Safety study of HRS-5817 injection in healthy adults
This early-phase trial tests the safety and tolerability of a new injection called HRS-5817 in healthy volunteers. It helps researchers understand how the drug moves through the body and what side effects it might have.
Hefei, AnhuiAges 18–55 - NCT06916806RecruitingPhase 1
Study of AZD5492 for lupus, myositis, or rheumatoid arthritis
This trial tests an investigational drug called AZD5492 for people with active lupus, inflammatory myositis, or rheumatoid arthritis who haven't responded well to other treatments. It aims to see if the drug is safe and how it works in the body.
Anniston, AlabamaAges 18–70 - NCT06829563RecruitingPhase 1
Testing safety of new diabetes drug RZ-629
This early-phase study tests a new medicine called RZ-629. It looks at how safe it is, how the body processes it, and how it works in both healthy people and people with type 2 diabetes. If you have diabetes, you can join if your blood sugar is well controlled on your current pills.
AdelaideAges 18–65 - NCT06755450RecruitingPhase 1
Study of AUR112 for advanced lymphoma or CLL
This trial tests a new oral medication called AUR112 for people with advanced lymphoma or CLL that has not responded to at least 2 prior treatments. The goal is to see if it is safe and how it works in the body.
Vadodara, GujaratAges 18–99 - NCT06736587RecruitingPhase 1
Safety study of DWP212525 in healthy adults
This trial studies a new drug (DWP212525) in healthy volunteers to see how safe it is and how the body processes it. If you are a generally healthy adult, you could help researchers learn about the drug's effects.
SeoulAges 19–55 - NCT06692933RecruitingEarly Phase 1
How hemp affects a common blood thinner
This study tests if a hemp product changes how the body processes the blood thinner clopidogrel (Plavix). You must be healthy, have used cannabis before without problems, and have a specific gene type that affects how these substances break down.
Spokane, WashingtonAges 21–64 - NCT03850574RecruitingPhase 1/Phase 2
Tuspetinib for relapsed or hard-to-treat AML
This early-phase study tests tuspetinib in people with AML that has come back or did not respond to treatment. The goal is to learn whether it is safe and tolerable, how the drug behaves in the body, and whether it shows signs of benefit.
Birmingham, AlabamaAges 18 years+ - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT06430385RecruitingPhase 1/Phase 2
Study of ION440 for MECP2 Duplication Syndrome
This trial tests an experimental medicine called ION440 for people with MECP2 Duplication Syndrome. The medicine is given as an injection into the spinal fluid, and the study aims to check its safety and how well it works.
San Diego, CaliforniaAges 2–65 - NCT06349473RecruitingPhase 1
Study of SR604 in healthy people and those with bleeding disorders
This study tests a new drug called SR604 to see if it is safe and how it works in the body. It is for healthy men and for people with hemophilia A, hemophilia B, or factor VII deficiency who have frequent bleeding or are on preventive treatment.
Glendale, CaliforniaAges 18–60 - NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65 - NCT06150716RecruitingPhase 1
Study of a new drug for Pelizaeus Merzbacher disease in boys
This trial is testing an experimental drug (ION356) given by a lumbar puncture to see if it is safe and how it works in boys with Pelizaeus Merzbacher disease (PMD). The drug is designed to target the genetic cause of PMD.
Atlanta, GeorgiaAges 2–17
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Common questions
- Are there clinical trials for pharmacokinetics and pharmacodynamics?
- Yes. Clin2 currently lists 135 recruiting pharmacokinetics and pharmacodynamics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pharmacokinetics and pharmacodynamics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pharmacokinetics and pharmacodynamics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.