Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,905 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07234890RecruitingPhase 2
Testing AV-001 to protect the brain during hemodialysis
This study tests a new medicine called AV-001 to see if it can protect the brain from damage caused by hemodialysis. If you qualify, you may help find a way to reduce thinking and memory problems linked to dialysis.
London, OntarioAges 18 years+ - NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06388863Recruiting
Fecal transplant for constipation in Parkinson's disease
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help relieve constipation in people with Parkinson's disease. FMT uses healthy donor stool to improve gut bacteria, which may ease constipation and possibly improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT07224269RecruitingEarly Phase 1
Terazosin for energy in ALS patients
This study tests whether a medication called terazosin can boost energy levels in people with ALS (Lou Gehrig's disease). The goal is to see if it helps slow down the disease by supporting cell energy.
Iowa City, IowaAges 18–80 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Birmingham, AlabamaAges 18–80 - NCT07223580RecruitingPhase 4
Steroid use for pain after kidney stone surgery
This trial tests if giving a corticosteroid during ureteroscopy (a scope procedure to remove kidney or ureter stones) can reduce pain afterward. If you are having this surgery and are not already on steroids or strong pain medicines, this study may help manage your recovery.
Scottsdale, ArizonaAges 18 years+ - NCT07226141RecruitingPhase 1/Phase 2
Valproate for persistent lazy eye in children and teens
This trial tests if the medication valproate (a seizure drug) can improve vision in children and teens aged 8-17 who still have a lazy eye (amblyopia) even after wearing glasses or patching. It may help if your child's vision has stopped getting better with standard treatments.
Boston, MassachusettsAges 8–17 - NCT07227948RecruitingPhase 2
Testing semaglutide for cocaine use disorder
This study tests whether semaglutide, a medication used for weight management, can help reduce cocaine use in people with cocaine use disorder. You may qualify if you have a body mass index (BMI) of 25 or higher and recently used cocaine.
Houston, TexasAges 18 years+ - NCT07226440RecruitingPhase 1/Phase 2
Trial to help firefighters reduce PFAS with a gastrointestinal product
This trial tests if taking a special tablet twice daily can help male firefighters lower PFAS chemicals in their bodies. It involves three visits in the San Francisco Bay Area, at-home blood tests, and weekly text surveys over about 6.5 months.
San Francisco, CaliforniaAges 18 years+ - NCT07229261Recruiting
MitoQ for blood vessel health in preeclampsia
This trial tests whether a supplement called MitoQ improves blood vessel function in pregnant people with preeclampsia. It may help manage blood pressure and reduce complications.
Milwaukee, WisconsinAges 18–50 - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07223814RecruitingPhase 3
Testing a new drug with standard chemo for AML
This trial adds an experimental drug called bleximenib to the usual chemotherapy for people newly diagnosed with AML who have certain genetic changes (NPM1 or KMT2A). The goal is to see if adding this drug helps the treatment work better.
Los Angeles, CaliforniaAges 18 years+ - NCT07229950RecruitingPhase 2
Experimental tablet for moderate to severe Ulcerative Colitis
This trial tests an experimental tablet, HRS-7085, for people with moderate to severe Ulcerative Colitis who haven't gotten enough help from standard treatments. The goal is to see if the drug can reduce inflammation and improve symptoms.
Chengdu, SichuanAges 18–75 - NCT07225517RecruitingPhase 1
Safety study of BIIB145 in healthy adults
This study tests a new drug called BIIB145 in healthy volunteers to see if it's safe and how the body handles it. It helps researchers learn about the drug before testing it in people with specific conditions.
Austin, TexasAges 18–55 - NCT07224360RecruitingPhase 2
Safety of a new drug for sickle cell pain
This study tests a new medicine called anumigilimab to see if it is safe for people with sickle cell disease. The study focuses on those who have had pain crises recently, to help manage and prevent them.
Little Rock, ArkansasAges 18 years+ - NCT07224581RecruitingPhase 3
Study of a new drug for GRIN-related developmental disorder
This trial tests a new drug for children with GRIN-related neurodevelopmental disorder caused by certain gene changes. The drug aims to improve seizures and other symptoms.
Los Angeles, CaliforniaAges 1 month–18 years - NCT07223229RecruitingPhase 2
Testing EI-001 for vitiligo that hasn't improved with other treatments
This study tests a new drug called EI-001 for people with non-segmental vitiligo (a type where white patches appear on both sides of the body). It is for those whose vitiligo has not gotten better with standard treatments like creams or light therapy, or who cannot use those treatments.
Huntington Beach, CaliforniaAges 18–65 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Santa Barbara, CaliforniaAges 1–35 - NCT07229937RecruitingPhase 2
Testing an experimental drug for high cholesterol
This study tests an experimental drug called HRS-1301 to see if it safely lowers LDL ("bad") cholesterol in people with high cholesterol. It is for adults who either already have artery disease or are at higher risk for it.
Harbin, HeilongjiangAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,905 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.