Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05302999RecruitingPhase 4
Early gabapentin for recovery after spinal cord injury
This trial studies whether starting gabapentin within 5 days after a traumatic spinal cord injury is safe and helpful for early recovery. It will mainly look at feasibility—whether patients can take the medicine and whether it affects early neurologic progress.
Cleveland, OhioAges 18 years+ - NCT05305911RecruitingPhase 2
SGLT2 drug after first heart attack to reduce heart damage
This Phase 2 trial tests whether an SGLT2 medicine started after a first STEMI heart attack can reduce ongoing heart muscle injury and scarring. It may help people who, based on heart imaging, have larger infarcts and ongoing microvascular damage.
Minneapolis, MinnesotaAges 18–75 - NCT05312424RecruitingPhase 1/Phase 2
Testing an annatto-based treatment for statin muscle pain
This early-stage trial tests whether an annatto-derived product (called GG) can help people who develop new muscle pain after starting or increasing a statin. If you recently noticed statin-related muscle aches, this study may see whether the treatment improves symptoms and safety.
Lubbock, TexasAges 40 years+ - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05315726Recruiting
Vibration therapy to reduce stiffness after stroke
This trial studies whether regular muscle vibration can reduce post-stroke muscle stiffness and improve how the brain and nerves adapt. If you’re in the right stage after stroke, it may help improve arm and hand movement.
Chalon-sur-SaôneAges 18 years+ - NCT05322213RecruitingPhase 1
THC study for blood sugar control in type 2 diabetes
This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.
La Jolla, CaliforniaAges 21–70 - NCT05324475Recruiting
Nutritional supplement to support immunity and energy in older adults
This trial tests whether a safe nutrition supplement can help older adults with malnutrition maintain immune function and energy (mitochondrial function). It may support recovery during rehabilitation, but you must meet specific nutrition and health criteria.
Lausanne, SwitzerlandAges 75 years+ - NCT05325580RecruitingPhase 3
IV magnesium vs placebo for sudden non-injury headaches
This trial tests whether giving magnesium sulfate through a vein in the emergency room can reduce sudden (non-injury) acute headaches compared with a placebo. It may help people whose headache comes on suddenly and is not caused by an injury.
MonastirAges 18–85 - NCT05327790RecruitingPhase 2
Fecal transplant to boost new biologic treatment for ulcerative colitis
This trial tests whether fecal microbiota transfer (a stool-based therapy) can improve outcomes when added to starting a new biologic medicine for ulcerative colitis. It compares fecal transplant versus placebo (a sham treatment) to see if symptoms and inflammation improve faster or more strongly.
Edmonton, AlbertaAges 18–75 - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05341583RecruitingPhase 3
Ensartinib after lung cancer surgery for ALK-positive patients
This Phase 3 trial tests whether ensartinib given after surgery can lower the risk of lung cancer coming back in people with ALK-positive non-small cell lung cancer. You may be eligible if your tumor was completely removed and your recovery and lab tests meet specific requirements.
TianjinAges 18 years+ - NCT05350371RecruitingPhase 1/Phase 2
Testing pirfenidone to treat severe acute pancreatitis
This early-stage hospital study tests whether pirfenidone is safe and tolerable for people with acute pancreatitis that may become severe. It may help by reducing the risk of complications, while researchers carefully track side effects.
Birmingham, AlabamaAges 18–85 - NCT05351229RecruitingPhase 4
Spinal morphine for pain control after lung surgery
This trial tests whether putting morphine into the spinal area during lung surgery can reduce pain after surgery for people having certain minimally invasive lung operations. It aims to improve comfort and possibly reduce the need for other pain medicines.
Chicago, IllinoisAges 18–80 - NCT05351801RecruitingPhase 2
Test cannabis-based treatment for nerve pain
This Phase 2 study tests cannabis-derived products to see if they reduce neuropathic (nerve-related) pain in veterans. It may help people whose pain is persistent and causes significant daily impact, especially if certain exam tests show allodynia (pain from normally non-painful touch).
San Diego, CaliforniaAges 21 years+ - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60 - NCT05361733RecruitingPhase 1
Safety and blood-drug study of XFB19 in healthy adults
This Phase 1 study tests whether XFB19 is safe and tolerable in healthy adults and how the drug moves through the body (what the blood levels look like). You would be in the study to help researchers understand early safety and dosing information.
Knoxville, TennesseeAges 18–55 - NCT05362292RecruitingPhase 4
Treating bladder leakage to support mind and body health
This study tests medicines to reduce “urgency” urine leakage (when you suddenly feel you must go) and to see whether improving bladder control also helps overall mental and physical health. You may be eligible if you have had these symptoms for at least 3 months and can follow the study plan.
Palo Alto, CaliforniaAges 60 years+ - NCT05367245RecruitingPhase 2
Butyrate supplement for Gulf War illness symptoms
This Phase 2 study tests whether a calcium–magnesium butyrate supplement can reduce symptoms of Gulf War Illness (GWI), especially by targeting gut and immune-related pathways. You may be eligible if you’re a Gulf War–era veteran with moderate-to-severe physical symptoms and no conditions or medicines that could explain them instead.
Long Beach, CaliforniaAges 40–70 - NCT05378815Recruiting
Platelet injections for knee arthritis pain
This study tests whether platelet-rich plasma (a treatment made from your own blood) can reduce symptoms of knee osteoarthritis. It focuses on people with specific types of knee pain and X-ray findings, and compares against rules around current pain medicines and injections.
Créteil, Val-De-MarneAges 40–79 - NCT05378334Recruiting
Test herbal treatment for lung cancer spread to bone
This trial studies whether the herbal medicine HGXJT can improve outcomes and safety for people with non-small cell lung cancer that has spread to the bones. It is designed for a specific lung cancer type (EGFR and ALK wild type) and people who have not had certain immune treatments before.
Guangzhou, GuangdongAges 18–75 - NCT05389930RecruitingPhase 2
Study how cannabis affects alcohol drinking
This Phase 2 study looks at whether using cannabis changes how much alcohol you drink. You may be able to take part if you’ve been drinking heavily and using cannabis recently and can meet health and screening requirements.
Providence, Rhode IslandAges 21–50 - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Anaheim, CaliforniaAges 50–90 - NCT05401578RecruitingPhase 3
Canakinumab for low blood sugar after stomach weight-loss surgery
This trial tests whether canakinumab can reduce frequent low blood sugar episodes after bariatric (weight-loss) surgery. It is designed for people who keep having low blood sugar despite dietary changes.
BaselAges 18–75 - NCT05405387RecruitingPhase 2
Budesonide to prevent serious diarrhea after stem cell transplant
This Phase 2 study tests whether budesonide can lower the chance of moderate-to-severe diarrhea in people with multiple myeloma who are getting an autologous stem cell transplant. It may help your comfort and reduce complications during the transplant recovery period.
Salt Lake City, UtahAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.