Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07447648Recruiting
Evinacumab for plaque buildup in HoFH
This observational study looks at how adding evinacumab to standard cholesterol-lowering therapy affects plaque in the heart arteries of people with homozygous familial hypercholesterolemia (HoFH). It compares those who started evinacumab within the last 2 years to those on standard therapy alone, using CT scans taken before and after treatment.
ParisAges 12 years+ - NCT07441148Recruiting
Digital vs. parent-led toothbrushing for kids
This study compares two ways of teaching children how to brush: with a digital tool or by having a parent show them. It looks at how well they brush and how their teeth look after brushing.
Los Angeles, CaliforniaAges 3–6 - NCT05850247RecruitingPhase 2
Study brain inflammation in carotid artery narrowing after stroke or TIA
This Phase 2 study looks at a protein called ficolin-2 and whether it relates to brain inflammation after a short stroke-like event or eye blood vessel blockage caused by narrowed carotid arteries. If you recently had symptoms from the carotid artery and meet imaging and health criteria, you may be offered study-related assessments to better understand the cause and help future treatment decisions.
BronAges 18 years+ - NCT04567030Recruiting
AI tool to help improve gum treatment outcomes
This trial tests whether an artificial intelligence (AI) system can help plan and improve results of gum (periodontal) treatment. You may be a good match if you have diagnosed periodontal disease and enough healthy teeth.
Kaohsiung CityAges 35–65 - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT06720168Recruiting
Erythritol air polisher for dental black stain treatment
This trial tests if a special cleaning tool using erythritol can safely remove black stains from teeth caused by bacteria. It may help people with at least two stained teeth who haven't used antibiotics recently or have certain health issues.
Alfara del Patriarca, ValenciaAges Any age - NCT06844942Recruiting
Improving heart artery imaging for chest pain diagnosis
This trial uses a special camera called OCT to take detailed pictures of the heart's arteries. It aims to see if these pictures help doctors better understand blockages and decide on treatment for stable chest pain.
Warsaw, Mazowieckie VoivodenshipAges 18 years+ - NCT07364565Recruiting
Green tea mouthwash for plaque and gum health
This trial tests whether a pure green tea mouthwash can reduce plaque and gum inflammation better than a placebo or an essential oils mouthwash. It may be a good option if you have healthy gums and are looking for a natural alternative.
Irbid, Irbid GovernorateAges 18 years+ - NCT07355400Recruiting
NeoPill device for reducing mouth bacteria in braces patients
This trial tests a device called NeoPill to reduce bacteria in the mouths of people with braces. It involves a single visit and may help control oral bacteria levels.
LimassolAges 18 years+ - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT07349875RecruitingPhase 4
Colchicine for non-severe coronary plaque: a trial
This trial tests if the anti-inflammatory drug colchicine can help people with non-severe coronary artery plaque seen on a CT scan. It may be an option if you have stable chest pain or related symptoms and your heart arteries are partly blocked but not severely.
NanjingAges 18 years+ - NCT07301034RecruitingPhase 3
Ziltivekimab for plaque after a heart attack
This study tests a drug called ziltivekimab to see if it can reduce fatty plaque buildup in heart arteries after a heart attack. It's for people who had a heart attack treated with a stent and have mild blockages in other arteries.
ViennaAges 18 years+ - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT07291609Recruiting
Microplastics in heart artery patients
This study looks for tiny plastic particles in the blood of people with chronic heart artery disease. You will have a standard CT scan and an invasive angiogram anyway, and researchers will check your blood samples for microplastics.
CasertaAges 18 years+ - NCT06882564RecruitingPhase 3
Resveratrol mouthwash for bad breath study
This trial tests whether a special mouthwash with resveratrol (a natural plant compound) can help reduce bad breath caused by gum-related bacteria. It might be a good option if you have bad breath from gingivitis (mild gum inflammation) and are a non-smoking dental student.
Baghdad, Bab Al-MoadhamAges 20–24 - NCT05077618Recruiting
Teeth bacteria study in seniors with and without Alzheimer’s
This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.
Nice, CHU de NICEAges 18–90 - NCT06291350Recruiting
Mouth bacteria in gum disease with blistering condition
This study looks at the bacteria in the mouth and gut of people with a blistering gum condition (mucous membrane pemphigoid) and gum disease. It aims to understand if certain bacteria are linked to the disease, which could lead to better treatments.
NiceAges 18 years+ - NCT06887894Recruiting
Studying unstable plaque in the carotid artery
This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.
Roma, RMAges 18 years+ - NCT06671106Recruiting
Mouthrinse for Teens with Early Gum Disease
This trial tests a special mouthrinse containing amine and zinc lactate to treat plaque-induced gingivitis (gum inflammation caused by plaque) in teenagers. If you or your teen have early gum disease and are eligible for free dental care through the Regional Health Service, this study may offer a home-based treatment option.
FerraraAges 12–14 - NCT07261306RecruitingEarly Phase 1
Methotrexate vs tofacitinib pills for plaque psoriasis
This study compares two oral pill treatments—methotrexate and tofacitinib—for people with chronic plaque psoriasis that is moderate to severe and hasn't responded well to creams. The goal is to see which pill works better at clearing skin.
Lahore, Punjab ProvinceAges 18–70 - NCT07265284RecruitingPhase 3
IBI112 for teens with moderate to severe plaque psoriasis
This study tests a new medicine called IBI112 for teens aged 12–18 with moderate to severe plaque psoriasis. It aims to see if the medicine is safe and can help clear skin better than placebo.
Beijing, Beijing MunicipalityAges 12–18 - NCT06214429Recruiting
Shear wave test for carotid plaque stiffness
This trial uses a special ultrasound technique called shear wave elastography to measure how stiff fatty deposits (plaques) are in your neck arteries. It aims to see whether plaque stiffness can help doctors better understand your stroke risk.
Botucatu, São PauloAges 18 years+ - NCT06912165RecruitingPhase 2
WD-890 for moderate to severe plaque psoriasis
This study tests an investigational drug called WD-890 for people with moderate-to-severe plaque psoriasis that hasn't responded well enough to other treatments. It may help reduce skin patches, scaling, and itching.
Nanjing, JiangsuAges 18–70
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.