Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT07794579RecruitingPhase 3
Study of orforglipron for people with overweight at risk of health problems
This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.
Anniston, AlabamaAges 18 years+ - NCT03308773Enrolling by invitation
Prevention program for people at risk of type 2 diabetes
This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.
Ages 18–100 - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+ - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT07504029Recruiting
Test if bitter melon peptides help control blood sugar
This trial is studying peptides from bitter melon (Momordica charantia) to see if they can help manage blood sugar levels in people with prediabetes. You may be eligible if you have higher-than-normal blood sugar but not full diabetes.
TaichungAges 30–65 - NCT07817290Recruiting
Food supplement for heart and blood sugar health in older adults
This study tests a specially designed food (a nutraceutical) to see if it can help improve heart health and blood sugar control in older adults. If you are 65 or older, have heart disease and mild diabetes or prediabetes, you might be able to join and potentially benefit from this simple dietary approach.
NovaraAges 65 years+ - NCT07808723Recruiting
Family program to prevent type 2 diabetes in African American and Hispanic households
This 12-week program helps African American and Hispanic families in Georgia lower their risk of type 2 diabetes by making healthy changes together. If you have prediabetes or are at risk, you and your teenager (ages 12-17) can join to learn about nutrition, exercise, and better health habits.
Atlanta, GeorgiaAges 12 years+ - NCT07804680Recruiting
Fitness and health in children with or without autism
This study looks at how fitness levels relate to body size and heart health in children and teens with or without autism. It uses existing medical records, so no new tests are needed.
Charlottesville, VirginiaAges 6–18 - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT07695675Recruiting
Community meals, walking, and blood sugar in older adults
This study tests if eating community meals and walking can help older adults with higher blood sugar. You will wear a glucose monitor and activity tracker while following a meal plan.
Changsha, HunanAges 60–79 - NCT07688278Recruiting
Diabetes screening for people with advanced gum disease
This trial tests whether checking blood sugar (HbA1c) at the dentist can find undiagnosed diabetes. It is for adults with advanced periodontitis (severe gum disease) who have not already been told they have diabetes.
SkåneAges 18 years+ - NCT07653048Recruiting
Personality traits and blood test results study
This trial looks at how personality traits might relate to certain blood test results that can affect health. It is for adults getting a regular health checkup who have already taken a personality quiz and had blood work done.
Târgu Mureş, Mureș CountyAges 18 years+ - NCT07650123Recruiting
7-Ketolithocholic Acid for Prediabetes Treatment
This study tests whether a compound called 7-ketolithocholic acid can help people with prediabetes (blood sugar levels higher than normal but not yet diabetic) prevent or delay developing type 2 diabetes. Participants will take the study medication while following a healthy diet and exercise plan.
BordigheraAges 18–70 - NCT07624500Recruiting
How Different Foods Affect Your Metabolism and Blood Sugar
This study tests how specific foods impact your body's ability to manage blood sugar and fat levels. You'll eat meals provided by the research team for about 12 weeks to help researchers understand which foods work best for people with high triglycerides (a type of blood fat) and insulin resistance (difficulty managing blood sugar).
Chicago, IllinoisAges 40–70 - NCT07603739Recruiting
Testing Almonds to Help Control Blood Sugar Levels
This study tests whether eating almonds before meals can help control blood sugar in adults with slightly elevated glucose levels. Researchers want to see if this simple dietary change could help prevent or delay type 2 diabetes.
Baton Rouge, LouisianaAges 25–50 - NCT07602023Recruiting
Fat Response and Diabetes Risk Study
This study looks at how your body processes fat after eating and measures certain blood markers to understand who might develop diabetes or complications. You'll eat a high-fat meal and have blood drawn to help doctors identify early warning signs.
Ferrara, FerraraAges 50–70 - NCT07536256Recruiting
Youth Resilience Through Native Hawaiian Culture in Wai'anae
This program connects young people in the Wai'anae community with culturally rooted activities and support to build resilience and improve physical and mental health. You'll work with other youth and community organizations that use Native Hawaiian values to help you thrive.
Waianae, HawaiiAges 12–25 - NCT07488767Enrolling by invitation
Food order study for diabetes with food insecurity
This study looks at whether changing the order you eat your food (like vegetables first, then carbs) can help people with prediabetes or diabetes who also experience food insecurity. It aims to find simple, low-cost ways to improve blood sugar control.
New York, New YorkAges 18–75 - NCT07478263Recruiting
Healthy eating trial for Latinas to prevent type 2 diabetes
This study tests a behavioral program designed to help Latinas with prediabetes improve their nutrition and eating patterns to prevent type 2 diabetes. It focuses on reducing cravings and building healthy habits.
La Jolla, CaliforniaAges 18–55 - NCT07472712Recruiting
Fruit and vegetable program for diabetes prevention
This program helps people with prediabetes lower their risk of type 2 diabetes by providing free fruits and vegetables along with cooking classes and support. It takes place over one year at a community location.
Richmond, VirginiaAges 18 years+ - NCT07450118Recruiting
Comparing two ways to lower diabetes risk
This study tests two different methods to help people at risk for type 2 diabetes. It aims to find which approach works best to prevent diabetes.
Newark, DelawareAges 18 years+ - NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74
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Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 136 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.