Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 140 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07695675Recruiting
Community meals, walking, and blood sugar in older adults
This study tests if eating community meals and walking can help older adults with higher blood sugar. You will wear a glucose monitor and activity tracker while following a meal plan.
Changsha, HunanAges 60–79 - NCT07603739Recruiting
Testing Almonds to Help Control Blood Sugar Levels
This study tests whether eating almonds before meals can help control blood sugar in adults with slightly elevated glucose levels. Researchers want to see if this simple dietary change could help prevent or delay type 2 diabetes.
Baton Rouge, LouisianaAges 25–50 - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT03851627RecruitingPhase 4
Testosterone for fatty liver in overweight men with diabetes
This trial compares testosterone undecanoate versus a placebo (inactive pill) to see if it lowers fat in the liver measured by MRI. It focuses on overweight or obese men who have prediabetes or type 2 diabetes and low testosterone confirmed by blood tests.
ViennaAges 18–75 - NCT04455867Recruiting
Study of type 2 diabetes risk and early treatment
This study looks at people who may be on the way to developing type 2 diabetes or who have it, to see how to help and better understand the condition. Depending on the part of the study you join, it may include brain scans and sleep testing.
Toronto, OntarioAges 18 years+ - NCT04607096Recruiting
Intermittent fasting to improve insulin in prediabetes or early type 2
This study tests whether intermittent fasting can improve how your body releases and uses insulin if you have prediabetes or early type 2 diabetes. It may help your blood sugar control without using insulin.
BerlinAges 18–70 - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT04657367Recruiting
Diabetes and prediabetes health tracking registry study
This study is a registry that collects information from people with diabetes, prediabetes, or normal blood sugar to better understand these conditions over time. It may help researchers learn which factors are linked to health changes, including future diabetes risk.
Bialystok, Podlaskie VoivodeshipAges Any age - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT05026723Recruiting
Food plan to improve health for HIV and type 2 diabetes
This study tests whether a personalized “food as medicine” approach can help people manage health related to HIV and type 2 diabetes or prediabetes risk. If you struggle with having enough healthy food, the program may focus on practical ways to improve diet and support healthier blood sugar.
Chapel Hill, North CarolinaAges 18 years+ - NCT05051436RecruitingPhase 4
Testing mirabegron and tadalafil to improve sugar control
This study looks at whether mirabegron and tadalafil can improve blood sugar control in people with prediabetes. It may help determine if these medicines can slow the move from prediabetes toward diabetes.
Lexington, KentuckyAges 35–65 - NCT05123963Recruiting
Timed lifestyle plan to improve blood sugar in prediabetes
This trial tests whether matching daily lifestyle habits to a 24-hour body rhythm can improve blood sugar levels in people with prediabetes. You may be asked to follow a detailed schedule and avoid certain medicines for a short time before study visits.
Sherbrooke, QuebecAges 45–75 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05301413RecruitingPhase 2
Diabetes prevention program tailored for Black adults at risk
This Phase 2 study tests a diabetes-prevention program designed for Black/African American adults, focusing on social factors that can affect health and weight. It aims to help participants lower their chances of developing type 2 diabetes through structured education and tracking.
Kansas City, MissouriAges 18 years+ - NCT05337098Recruiting
Sweetener study in older adults with prediabetes
This study tests whether eating non-nutritive sweeteners changes how your body handles sugar (glucose control). It may help researchers learn if sweeteners are helpful or harmful for people with prediabetes.
Blacksburg, VirginiaAges 40 years+ - NCT05351476Recruiting
Exercise program for metabolism in postmenopausal women
This trial studies whether a structured exercise program can improve how your body uses fat. It is designed for postmenopausal women with higher weight and prediabetes who are not currently exercising much.
Tallahassee, FloridaAges 50–75 - NCT05447806Recruiting
Diabetes decision help after an alert message
This study tests a computer system that helps clinicians make better diabetes decisions when an alert or disease-management message appears. It may help your care by guiding what actions the care team takes next.
Hershey, PennsylvaniaAges 18 years+ - NCT05776420RecruitingPhase 3
Healthy food vouchers to improve blood sugar control
This trial tests whether giving people a healthy food voucher helps lower blood sugar levels in people who have prediabetes or type 2 diabetes. It also aims to support people who struggle with food or money by improving access to healthier foods.
TorontoAges 19 years+ - NCT05799222Recruiting
Nutrition program for obesity and diabetes risk
This trial tests a medically guided nutrition program to help improve weight and blood sugar in adults with obesity or early diabetes risk. It specifically targets people who meet income guidelines and don’t already use most diabetes or anti-obesity medicines.
Boston, MassachusettsAges 18–65 - NCT05835037RecruitingPhase 4
Zinc supplement study for prediabetes blood sugar control
This study tests whether taking zinc can improve how your body controls blood sugar in people with prediabetes. It may help slow the progression toward type 2 diabetes, but you would need to meet specific health and medication criteria.
Lancaster, PennsylvaniaAges 18–80
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Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 140 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.