Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 140 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06739993Recruiting
Can breathing exercises improve blood sugar in prediabetes?
This study tests if a special breathing technique (heart rate variability biofeedback) can help people with prediabetes improve their blood sugar control. You will attend screening visits and practice breathing exercises at home to see if this lowers your risk of developing diabetes.
Mainz, MainzAges 18–65 - NCT06750783RecruitingPhase 4
Xuezhikang vs Atorvastatin for high cholesterol and prediabetes
This trial compares two treatments (Xuezhikang, a red yeast rice supplement, and Atorvastatin, a common statin) to see which works better for lowering cholesterol in people with prediabetes. It may help you understand if a natural option is as effective as a standard medication.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06782906Recruiting
More activity, no evening snacks for teen prediabetes
This study tests whether increasing physical activity and stopping evening snacking can improve the health of teenagers with prediabetes. It may help you manage your blood sugar and prevent type 2 diabetes.
Houston, TexasAges 12–18 - NCT06841796Recruiting
YMCA healthy lifestyle program for prediabetes
This study offers a YMCA-led healthy lifestyle program for adults with prediabetes to help manage blood sugar and prevent type 2 diabetes. Participants will learn healthier habits and may use a continuous glucose monitor (CGM) to track how food and activity affect blood sugar levels.
Port Huron, MichiganAges 18 years+ - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06967558RecruitingPhase 2
GLP-1 hormone role in prediabetes
This study looks at how a hormone called GLP-1, made in the pancreas, affects blood sugar levels in people with borderline high blood sugar (prediabetes). It may help find new ways to prevent diabetes.
Rochester, MinnesotaAges 25–70 - NCT06980701Recruiting
Personalized oral hygiene advice for people with prediabetes
This trial tests whether personalized advice from a dentist or an AI can improve the oral and overall health of people with prediabetes. You may benefit if you have prediabetes and are willing to improve your daily oral care routine.
Hong Kong, Sai Ying PunAges 18 years+ - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT07131384Recruiting
Nitrate supplement and metformin for prediabetes
This trial tests whether adding a nitrate supplement to metformin helps people with prediabetes. It looks at how the two treatments interact, especially when you start exercising. The study might help you if you have prediabetes, are between 18 and 60 years old, and don't exercise much.
Charlottesville, VirginiaAges 18–60 - NCT07140848Recruiting
CGM-enhanced program to prevent type 2 diabetes in prediabetes
This trial tests whether adding continuous glucose monitors (CGMs) to a proven lifestyle program helps adults with prediabetes prevent type 2 diabetes. You'll attend coaching sessions and wear a small sensor to track your blood sugar.
Buffalo, New YorkAges 18 years+ - NCT07149064Recruiting
Effect of Nextida GC-B on Blood Sugar in Prediabetes
This study tests whether a nutritional supplement called Nextida GC-B helps control blood sugar in people who either have normal blood sugar or prediabetes. It looks at how the supplement affects blood sugar levels over time using a continuous glucose monitor.
London, OntarioAges 18 years+ - NCT07171281Recruiting
Timing meals to improve blood sugar and heart health
This study tests whether eating at specific times of day can help control blood sugar and improve heart health in people with prediabetes or type 2 diabetes. It compares two different eating schedules to see which works better.
NuthetalAges 18–75 - NCT07195994Recruiting
Study of an investigational product with or without semaglutide for blood sugar
This trial tests an investigational product to see how well it controls blood sugar in adults with prediabetes or type 2 diabetes. Some participants will also take the diabetes medication semaglutide to compare effects.
London, OntarioAges 18 years+ - NCT07235358Recruiting
Pecan snacking for prediabetes health study
This study tests if eating pecans daily as a snack can improve heart health and blood sugar control in people with prediabetes. You would replace typical sugary or fatty snacks with pecans for several weeks, and researchers will track changes in your cholesterol and blood sugar.
University Park, PennsylvaniaAges 25–65 - NCT07546409Recruiting
Do ketones help thinking in older adults with prediabetes?
This study looks at whether a supplement called ketones can improve thinking and memory in older adults who have prediabetes but not diabetes or memory problems. You will take the supplement, have brain scans, and complete thinking tests.
Birmingham, AlabamaAges 60–75 - NCT07261475RecruitingEarly Phase 1
Saffron petal extract for weight and blood sugar
This study tests a water extract from saffron flower petals to see if it helps with weight loss or blood sugar control in people with obesity or prediabetes. It's an early-phase trial, so it's looking at safety and how the body handles the extract.
IzolaAges 40–65 - NCT07286747RecruitingPhase 2
Nicotinic Acid for Reversing Prediabetes
This trial tests whether a controlled-release form of nicotinic acid (a type of vitamin B3) can help people with prediabetes get their blood sugar back to normal. It also looks at how the treatment affects liver health.
KielAges 18–79 - NCT07477249Recruiting
Continuous glucose monitor for prediabetes
This trial tests if wearing a continuous glucose monitor can help people with prediabetes understand their blood sugar patterns. You would wear a small sensor on your arm, and the results may help you make changes to prevent diabetes.
Los Angeles, CaliforniaAges 35 years+ - NCT07491653Recruiting
Fiber app study for prediabetes
This trial tests if a smartphone app that helps you eat more fiber can improve blood sugar levels in young adults with prediabetes. You'll use the app from home and meet with the study team near Tulsa.
Tulsa, OklahomaAges 18–39 - NCT07505745RecruitingPhase 2
A study on MOTS-c for improving insulin sensitivity
This trial tests an investigational peptide (MOTS-c) to see if it can improve how your body uses insulin. It's for adults with prediabetes and excess weight who are not yet on diabetes medications and can maintain a stable diet and activity level for 12 weeks.
Shenzhen, GuangdongAges 18–65 - NCT07525622Recruiting
Learning carbohydrate counting to manage prediabetes
This study teaches adults with prediabetes how to count carbohydrates in their diet as a way to help manage blood sugar without medication. You'll learn practical skills to make healthier food choices.
Istanbul, PendikAges 18 years+ - NCT07598773Enrolling by invitation
Continuous glucose monitoring study for prediabetes and type 2 diabetes
This study asks you to wear a glucose monitor and smart ring for several months to help researchers understand how blood sugar changes throughout the day in people with prediabetes or type 2 diabetes. The goal is to learn how lifestyle and medications affect blood sugar control.
San Francisco, CaliforniaAges 18 years+ - NCT07504029Recruiting
Test if bitter melon peptides help control blood sugar
This trial is studying peptides from bitter melon (Momordica charantia) to see if they can help manage blood sugar levels in people with prediabetes. You may be eligible if you have higher-than-normal blood sugar but not full diabetes.
TaichungAges 30–65 - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+
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Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 140 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.