Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 137 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06750783RecruitingPhase 4
Xuezhikang vs Atorvastatin for high cholesterol and prediabetes
This trial compares two treatments (Xuezhikang, a red yeast rice supplement, and Atorvastatin, a common statin) to see which works better for lowering cholesterol in people with prediabetes. It may help you understand if a natural option is as effective as a standard medication.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07195994Recruiting
Study of an investigational product with or without semaglutide for blood sugar
This trial tests an investigational product to see how well it controls blood sugar in adults with prediabetes or type 2 diabetes. Some participants will also take the diabetes medication semaglutide to compare effects.
London, OntarioAges 18 years+ - NCT07171281Recruiting
Timing meals to improve blood sugar and heart health
This study tests whether eating at specific times of day can help control blood sugar and improve heart health in people with prediabetes or type 2 diabetes. It compares two different eating schedules to see which works better.
NuthetalAges 18–75 - NCT07149064Recruiting
Effect of Nextida GC-B on Blood Sugar in Prediabetes
This study tests whether a nutritional supplement called Nextida GC-B helps control blood sugar in people who either have normal blood sugar or prediabetes. It looks at how the supplement affects blood sugar levels over time using a continuous glucose monitor.
London, OntarioAges 18 years+ - NCT07140848Recruiting
CGM-enhanced program to prevent type 2 diabetes in prediabetes
This trial tests whether adding continuous glucose monitors (CGMs) to a proven lifestyle program helps adults with prediabetes prevent type 2 diabetes. You'll attend coaching sessions and wear a small sensor to track your blood sugar.
Buffalo, New YorkAges 18 years+ - NCT07131384Recruiting
Nitrate supplement and metformin for prediabetes
This trial tests whether adding a nitrate supplement to metformin helps people with prediabetes. It looks at how the two treatments interact, especially when you start exercising. The study might help you if you have prediabetes, are between 18 and 60 years old, and don't exercise much.
Charlottesville, VirginiaAges 18–60 - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT06980701Recruiting
Personalized oral hygiene advice for people with prediabetes
This trial tests whether personalized advice from a dentist or an AI can improve the oral and overall health of people with prediabetes. You may benefit if you have prediabetes and are willing to improve your daily oral care routine.
Hong Kong, Sai Ying PunAges 18 years+ - NCT06967558RecruitingPhase 2
GLP-1 hormone role in prediabetes
This study looks at how a hormone called GLP-1, made in the pancreas, affects blood sugar levels in people with borderline high blood sugar (prediabetes). It may help find new ways to prevent diabetes.
Rochester, MinnesotaAges 25–70 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06782906Recruiting
More activity, no evening snacks for teen prediabetes
This study tests whether increasing physical activity and stopping evening snacking can improve the health of teenagers with prediabetes. It may help you manage your blood sugar and prevent type 2 diabetes.
Houston, TexasAges 12–18 - NCT06739993Recruiting
Can breathing exercises improve blood sugar in prediabetes?
This study tests if a special breathing technique (heart rate variability biofeedback) can help people with prediabetes improve their blood sugar control. You will attend screening visits and practice breathing exercises at home to see if this lowers your risk of developing diabetes.
Mainz, MainzAges 18–65 - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06633575Recruiting
Exercise study for prediabetes in Han Chinese adults
This study looks at how an exercise program can improve prediabetes (a condition where blood sugar is higher than normal but not yet diabetes) in adults of Han Chinese descent. It aims to find the best types of exercise to help control blood sugar and prevent diabetes.
Shanghai, Shanghai MunicipalityAges 19–55 - NCT06359418Recruiting
Acupuncture for prediabetes and obesity
This study tests whether acupuncture can help people with prediabetes and obesity manage their condition. If you have both higher-than-normal blood sugar and excess weight, this trial may offer a non-medication approach to improve your health.
BeijingAges 18–64 - NCT06477900Recruiting
Text message reminders for weight loss in prediabetes
This trial tests whether getting regular text message reminders can help people with prediabetes lose more weight during a health program. It is for adults in Réunion who are already part of a local prediabetes support program.
Saint-Louis, RéunionAges 18 years+ - NCT06365723Recruiting
Walking in Nature vs. City for Prediabetes
This study compares walking in natural green spaces (like parks) versus walking in built environments (like city streets) for adults with prediabetes. You will be asked to walk three times a week for 30 minutes for 4 weeks in each setting, and researchers will see how your body responds.
Lake Forest, IllinoisAges 25–64 - NCT06054035RecruitingPhase 4
SGLT2 inhibitor for prediabetes complications
This trial tests if a drug called dapagliflozin (an SGLT2 inhibitor) can help prevent complications in people with prediabetes when added to lifestyle changes. It aims to see if this approach works better than lifestyle changes alone.
BerlinAges 35–75 - NCT06025292Recruiting
Does eating lean pork help control blood sugar in prediabetes?
This study tests whether eating lean pork loin for a few days can improve how your body handles protein and blood sugar. If you have prediabetes, you may be able to join a short 4-day meal study at the University of Arkansas.
Little Rock, ArkansasAges 40–65 - NCT05745441Recruiting
Dinner routine study for weight and prediabetes health
This study tests whether changing your dinner timing and routine can improve health related to weight and blood sugar in people with obesity and prediabetes (or healthy weight). You’ll follow a set dinner schedule and complete study visits while the team monitors outcomes.
Baltimore, MarylandAges 18–50 - NCT05119179RecruitingPhase 4
Testing how genetics affect GLP-1 response in prediabetes
This study looks at how your genes may change how well a GLP-1–type medicine works to improve prediabetes. It focuses on adults at higher risk of developing diabetes, especially people of Mexican-American background.
Brownsville, TexasAges 18 years+ - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04455867Recruiting
Study of type 2 diabetes risk and early treatment
This study looks at people who may be on the way to developing type 2 diabetes or who have it, to see how to help and better understand the condition. Depending on the part of the study you join, it may include brain scans and sleep testing.
Toronto, OntarioAges 18 years+ - NCT06115876Recruiting
Kuwait diabetes long-term follow-up study
This study checks in on people with prediabetes or type 2 diabetes who were part of an earlier Kuwait diabetes study. It aims to understand how their condition has changed and what health care they may need.
Kuwait CityAges 21–75
Hear when a new Prediabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 137 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.