Clinical trials
Premature Infant clinical trials
Below are recruiting premature infant clinical trials, each written for real people, not researchers. We’re tracking 108 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04294368Recruiting
Fortifying donor breast milk for very premature babies
This study tests whether adding extra nutrition (fortifying) to donated breast milk helps very premature infants grow better and safely. You might be offered a fortified donor milk feeding plan if your baby meets the timing and medical criteria.
New York, New YorkAges 1 day–3 weeks - NCT07251790Recruiting
Better breathing support for very preterm babies
This trial tests different ways to help very preterm babies when they are first taken off a breathing machine and switched to CPAP. It aims to find the safest and most effective breathing support to help them breathe on their own.
Melbourne, VictoriaAges birth+ - NCT07622563Recruiting
Automatic oxygen control for premature babies on breathing support
This trial tests a device that automatically adjusts oxygen levels for premature babies who need help breathing through tubes or masks in their nose. The goal is to keep oxygen levels in a safer, more stable range without needing staff to manually adjust it constantly.
LondonAges 5 months–8 months - NCT05243043Recruiting
Help for mothers needing premature baby resuscitation
This trial tests an interactive phone or app-style tool to help mothers prepare for and understand what happens if their premature baby needs breathing support at birth. It may help you feel more informed and supported during a high-stress time.
Iowa City, IowaAges 18–60 - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT03797183Recruiting
Check heart and lung function using a painless chest scan
This study uses a noninvasive scan that measures electrical signals across the chest to better understand breathing and heart-related circulation problems. It may help doctors learn what to monitor and how conditions like lung/airway pressure and vessel narrowing progress.
Aurora, ColoradoAges 2 weeks–40 years - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT04114435Recruiting
Heart and lung testing in extremely premature babies
This study looks at how the hearts and lungs work in babies born very early (before 29 weeks). It may help researchers understand why some babies develop breathing and heart circulation problems and how to measure their recovery.
Montreal, QuebecAges 1 week–5 years - NCT04911452Recruiting
Calmer NICU care for very preterm babies
This study tests a calmer approach in the NICU to help very preterm babies grow and develop their brains. It may be helpful if your baby needs breathing support and is in the early weeks of life.
Vancouver, British ColumbiaAges 6 months–7 months - NCT05017389Recruiting
Long-term health follow-up for premature newborns
This study follows babies born early (premature) over the long term to learn how they grow and develop. It mainly helps doctors understand long-term health needs after early birth.
Shanghai, Shanghai MunicipalityAges 2 weeks–4 months - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT05223192Recruiting
Testing music to improve breathing and brain oxygen in preemies
This study looks at whether planned music sessions can help preterm babies breathe more steadily and improve oxygen reaching the brain. It may help staff learn how to use music therapy safely for newborns in the NICU.
New York, New YorkAges 6 months–9 months - NCT05340465RecruitingPhase 2
IV iron in preterm babies to reduce blood transfusions
This Phase 2 study tests whether giving a specific IV iron (darbe plus IV iron) can help preterm babies need fewer blood transfusions while still keeping their iron levels in a safe range. It focuses on babies in the NICU who were born early, and it compares transfusion use and iron sufficiency over time.
Seattle, WashingtonAges Up to 3 days - NCT05380401Recruiting
DHA and ARA milk fats for very early preterm babies
This study looks at how adding two specific milk fats (DHA and ARA) through enteral feeding affects metabolism in very early preterm infants. It may help researchers understand what these nutrients do in babies born around 25–30 weeks gestation.
Los Angeles, CaliforniaAges Up to 8 months - NCT05675397Recruiting
Donor milk supplement for very small preterm babies
This study looks at giving donor human milk to very low-birth-weight preterm babies when a mother’s own milk is not enough during the first three weeks. It may help babies get human milk instead of formula during that early period.
AthensAges 1 day–3 weeks - NCT05849077Recruiting
Testing oxygen saturation targets during newborn resuscitation
This study looks at the best oxygen saturation targets and resuscitation approach for very premature babies right after birth. It may help clinicians guide breathing support more safely in the first minutes of life.
Dallas, TexasAges birth–10 minutes - NCT05865977Recruiting
Test a breathing check to prevent breathing tube failure in preemies
This study checks a specific bedside breathing test (called an SBT) to see if it can better predict when a premature baby is likely to fail extubation (having the breathing tube removed). If the test is accurate, it may help doctors time tube removal more safely and reduce complications.
Chongqing, Chongqing MunicipalityAges 2 days–6 months - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT06063122Recruiting
Device to help preterm babies tell speech sounds apart
This study tests a new device that plays special sounds to help preterm babies learn to tell different speech sounds apart. It is for babies born between 32 and 35 weeks of pregnancy to see if the device can improve their hearing and brain development.
Atlanta, GeorgiaAges 7 months–8 months - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT06256406Recruiting
Comfort, kangaroo care, and music therapy for NICU newborns
This trial tests whether a comfortable environment, kangaroo care (skin-to-skin contact), and music therapy can help newborns in the neonatal intensive care unit (NICU). It aims to see if these gentle approaches improve their well-being.
Catania, SicilyAges birth–3 years - NCT06627374Recruiting
Ultrasound to check duct closure in premature babies
This study uses ultrasound to see if a heart blood vessel called the ductus arteriosus has closed after treatment in premature infants. It aims to find a better way to monitor the response to treatment without X-rays.
Roma, romaAges Up to 4 weeks - NCT06788470RecruitingPhase 1/Phase 2
Stem cell therapy for severe lung disease in premature babies
This trial tests whether umbilical cord stem cells can help premature babies with severe bronchopulmonary dysplasia (a chronic lung disease) who still need a breathing tube after standard hormone treatment. The goal is to see if it is safe and improves their lung condition.
Hangzhou, ZhejiangAges 8 months+
Hear when a new Premature Infant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for premature infant?
- Yes. Clin2 currently lists 108 recruiting premature infant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature infant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature infant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.