Clinical trials
Premature Infant clinical trials
Below are recruiting premature infant clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05675397Recruiting
Donor milk supplement for very small preterm babies
This study looks at giving donor human milk to very low-birth-weight preterm babies when a mother’s own milk is not enough during the first three weeks. It may help babies get human milk instead of formula during that early period.
AthensAges 1 day–3 weeks - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT06256406Recruiting
Comfort, kangaroo care, and music therapy for NICU newborns
This trial tests whether a comfortable environment, kangaroo care (skin-to-skin contact), and music therapy can help newborns in the neonatal intensive care unit (NICU). It aims to see if these gentle approaches improve their well-being.
Catania, SicilyAges birth–3 years - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT07667049RecruitingPhase 1
Gut health study for preterm infants
This study looks at how the gut works in premature babies to better understand digestion and health. It may help improve care for newborns born early.
Baltimore, MarylandAges Up to 4 days - NCT07652684RecruitingPhase 4
Fat supplement to help premature babies' lungs
This study tests whether adding a special fat supplement to the feeding of very premature babies can help prevent or reduce lung damage, which is common in babies born early. The supplement is given through a feeding tube.
ThessalonikiAges 6 months–7 months - NCT07622563Recruiting
Automatic oxygen control for premature babies on breathing support
This trial tests a device that automatically adjusts oxygen levels for premature babies who need help breathing through tubes or masks in their nose. The goal is to keep oxygen levels in a safer, more stable range without needing staff to manually adjust it constantly.
LondonAges 5 months–8 months - NCT04911452Recruiting
Calmer NICU care for very preterm babies
This study tests a calmer approach in the NICU to help very preterm babies grow and develop their brains. It may be helpful if your baby needs breathing support and is in the early weeks of life.
Vancouver, British ColumbiaAges 6 months–7 months - NCT06788470RecruitingPhase 1/Phase 2
Stem cell therapy for severe lung disease in premature babies
This trial tests whether umbilical cord stem cells can help premature babies with severe bronchopulmonary dysplasia (a chronic lung disease) who still need a breathing tube after standard hormone treatment. The goal is to see if it is safe and improves their lung condition.
Hangzhou, ZhejiangAges 8 months+ - NCT07442669Recruiting
Lung ultrasound for surfactant decision in premature babies
This trial uses a lung ultrasound score, a type of ultrasound, to decide when to give surfactant (a medicine that helps lungs work) to premature babies born between 27 and 35 weeks of pregnancy. It aims to reduce the need for more breathing support and avoid side effects.
Hackensack, New JerseyAges 6 months–8 months - NCT07410858Recruiting
Virtual reality education for NICU parents
This study tests whether a virtual reality program can help parents learn about their baby's care in the NICU. If you join, you would use a VR headset to learn while your baby is in the hospital.
Ismailia, Ismailia, Egypt.Ages 18 years+ - NCT07344714Recruiting
Predicting breathing help needs for newborns in NICUs
This study looks at newborns in a lower-level NICU to see which ones will need extra breathing support. The goal is to better predict which babies can be kept at their current hospital instead of being moved.
Rochester, MinnesotaAges 7 months–9 months - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT07120971RecruitingEarly Phase 1
Metformin study for premature babies with lung disease
This study tests whether metformin, a medicine used for diabetes, can help premature babies with chronic lung disease (bronchopulmonary dysplasia, or BPD) breathe better. It may reduce the need for breathing machines.
Milwaukee, WisconsinAges 1 week–6 months - NCT07098910Recruiting
Surfactant therapy for premature babies with breathing problems
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
HanoiAges Up to 2 days - NCT07060573Recruiting
Parent-led mouth stimulation to help premature babies suck
This study tests if gentle mouth stimulation done by parents helps premature babies (around 34–36 weeks) learn to suck better. If your baby is stable and doesn’t have certain face or muscle conditions, this may help them feed sooner.
Guadalajara, JaliscoAges 8 months–8 months - NCT04114435Recruiting
Heart and lung testing in extremely premature babies
This study looks at how the hearts and lungs work in babies born very early (before 29 weeks). It may help researchers understand why some babies develop breathing and heart circulation problems and how to measure their recovery.
Montreal, QuebecAges 1 week–5 years - NCT05849077Recruiting
Testing oxygen saturation targets during newborn resuscitation
This study looks at the best oxygen saturation targets and resuscitation approach for very premature babies right after birth. It may help clinicians guide breathing support more safely in the first minutes of life.
Dallas, TexasAges birth–10 minutes - NCT05243043Recruiting
Help for mothers needing premature baby resuscitation
This trial tests an interactive phone or app-style tool to help mothers prepare for and understand what happens if their premature baby needs breathing support at birth. It may help you feel more informed and supported during a high-stress time.
Iowa City, IowaAges 18–60 - NCT06063122Recruiting
Device to help preterm babies tell speech sounds apart
This study tests a new device that plays special sounds to help preterm babies learn to tell different speech sounds apart. It is for babies born between 32 and 35 weeks of pregnancy to see if the device can improve their hearing and brain development.
Atlanta, GeorgiaAges 7 months–8 months - NCT03797183Recruiting
Check heart and lung function using a painless chest scan
This study uses a noninvasive scan that measures electrical signals across the chest to better understand breathing and heart-related circulation problems. It may help doctors learn what to monitor and how conditions like lung/airway pressure and vessel narrowing progress.
Aurora, ColoradoAges 2 weeks–40 years - NCT05380401Recruiting
DHA and ARA milk fats for very early preterm babies
This study looks at how adding two specific milk fats (DHA and ARA) through enteral feeding affects metabolism in very early preterm infants. It may help researchers understand what these nutrients do in babies born around 25–30 weeks gestation.
Los Angeles, CaliforniaAges Up to 8 months
Hear when a new Premature Infant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for premature infant?
- Yes. Clin2 currently lists 104 recruiting premature infant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature infant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature infant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.