Clinical trials
Primary Hypercholesterolemia or Mixed Hyperlipidemia clinical trials
Below are recruiting primary hypercholesterolemia or mixed hyperlipidemia clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06568471RecruitingPhase 3
Study of HST101 for high cholesterol in Chinese patients
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07421297RecruitingPhase 3
Study of SYH2053 for high cholesterol in Chinese adults
This trial tests a new medication called SYH2053 for people with high cholesterol or mixed high cholesterol and triglycerides. If you have high LDL cholesterol and are not taking strong cholesterol medicines, you may be able to join. The study will see if this drug is safe and works well.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06686615Recruiting
Study of a triple cholesterol medicine combination in high-risk patients
This study tests a cholesterol-lowering combination of three medicines: bempedoic acid, ezetimibe, and a statin (atorvastatin or rosuvastatin). It is for people with high cholesterol, especially those at high risk for heart problems, who need stronger treatment.
Braunau am InnAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT07614958RecruitingPhase 3
Testing a new cholesterol medicine against bempedoic acid
This study compares two new medicines—obicetrapib and bempedoic acid—to see which one better lowers cholesterol in people whose cholesterol remains high despite taking standard medications. If your cholesterol isn't controlled well enough with current drugs, this trial may help you access an experimental treatment.
Stockton-on-TeesAges 18 years+ - NCT06770543Recruiting
Study of Leqvio for high cholesterol in Korea
This study is for adults in Korea with high cholesterol who need a new option because statins aren't working well enough or cause side effects. It will look at how well the medication Leqvio works in everyday medical practice.
Yangsan, Gyeongsangnam-doAges 18–100 - NCT06314919Recruiting
Study of a combination pill for high cholesterol
This study tests a single pill that combines two cholesterol-lowering medicines (pitavastatin and ezetimibe). It may be a good fit if you already take a statin or a statin plus ezetimibe and your doctor wants to adjust your treatment.
SeoulAges 19 years+ - NCT07223658RecruitingPhase 1/Phase 2
Study of ARO-DIMERPA for high triglycerides and cholesterol
This trial tests an experimental drug, ARO-DIMERPA, for people with very high triglycerides and cholesterol. It aims to lower those levels and reduce heart risks.
Charlestown, New South WalesAges 18 years+ - NCT07206472Recruiting
Study of bempedoic acid for high cholesterol
This study observes patients with high cholesterol or mixed lipid disorders who are taking bempedoic acid, alone or with ezetimibe, to see how it works in real life. It aims to gather information that may help doctors better manage cholesterol.
Belo HorizonteAges 18 years+ - NCT06822946RecruitingPhase 2
Zhibitai Capsules for High Cholesterol
This trial tests if Zhibitai Capsules can lower high cholesterol in people with primary hyperlipidemia (high fat levels in the blood). It may be a treatment option for those who cannot take standard medications.
Changsha, HunanAges 18–75 - NCT07695597RecruitingPhase 2
Study of SYH2070 for people with high cholesterol and triglycerides
This trial tests an investigational injection called SYH2070 to lower cholesterol and triglycerides in people who are already on a stable statin therapy. It may be a new option for those with mixed hyperlipidemia who need additional lipid control.
Hangzhou, ZhejiangAges 18 years+ - NCT06646354Enrolling by invitationPhase 3
Study of two experimental drugs for high blood pressure and cholesterol
This trial tests whether taking two experimental drugs together can safely lower both high blood pressure and high cholesterol. It may be an option if you have both conditions and your blood pressure is not extremely high.
SeoulAges 19 years+ - NCT06752772Recruiting
Wearable health coaching for blood pressure and weight
This study tests a digital health coaching program that uses a smartwatch and smartphone to help people manage conditions like high blood pressure, pre-diabetes, or weight. It aims to see if wearable technology can improve your health with personalized coaching.
SingaporeAges 21–75 - NCT03989167Recruiting
Decision support for inherited high cholesterol records
This trial tests a computer “decision support” tool for primary care clinics to help manage familial hypercholesterolemia, an inherited condition that can cause very high cholesterol. It may help clinics make more consistent decisions using patients’ health records.
LinköpingAges 18–80 - NCT04073797Recruiting
PET scan study of inflammation and cholesterol-lowering treatment
This study uses PET/CT and related scans to measure inflammation in artery plaque and how cholesterol-lowering treatment changes it. It may help researchers understand which treatments reduce artery inflammation for people with heart or blood-vessel disease and high LDL (“bad”) cholesterol.
CambridgeAges 18–99 - NCT07634484RecruitingPhase 4
Pemafibrate for high cholesterol not controlled by statins
This study tests whether pemafibrate, a new medication, can lower cholesterol better when added to statin treatment in patients whose cholesterol remains high despite taking statins regularly. The goal is to see if this combination reduces heart disease risk.
HokkaidoAges 18 years+ - NCT05912387RecruitingEarly Phase 1
Testing statin treatment in primary sclerosing cholangitis
This early study looks at how a statin (cholesterol-lowering medicine) affects people with primary sclerosing cholangitis (PSC) by measuring changes using multiple types of health data. It may help researchers understand which people benefit and how PSC biology changes with treatment.
Stanford, CaliforniaAges 18–80 - NCT02208869Recruiting
Registry for inherited high cholesterol (familial hypercholesterolemia)
This registry collects information from people with inherited high cholesterol to better understand the condition and care needs. You may be invited to share blood and medical test results, especially your cholesterol and related health history.
ChelyabinskAges 7–80 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT05284513Enrolling by invitation
Care team study for families with high cholesterol
This study tests a “reach everyone” approach in primary care clinics to improve care for people with familial hypercholesterolemia (families with very high cholesterol). It may help families get recognized sooner and get the right follow-up.
Multiple Locations, PennsylvaniaAges 26 years+ - NCT05482386Recruiting
Blood and health traits study in older people on statins
This study looks at blood markers (“biomarkers”) to better understand health risk in older adults who have multiple long-term illnesses and are taking statin medicines. It may help researchers predict outcomes and improve care for people with complex health needs.
BernAges 70 years+ - NCT05362929Recruiting
Laser treatment for acne scars in darker skin tones
This study tests a new type of laser treatment for acne scars in people with darker skin tones. It aims to see if the laser is effective and safe for improving the appearance of scars.
Elmsford, New YorkAges 18 years+ - NCT05482399Recruiting
Study statin use and silent artery plaque in older adults
This study looks at “subclinical atherosclerosis,” meaning early or silent plaque buildup in the arteries, in older people already taking statins. It may help doctors understand how well statins can slow artery damage in people with multiple health conditions.
BernAges 70 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Foley, AlabamaAges 18–75
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Common questions
- Are there clinical trials for primary hypercholesterolemia or mixed hyperlipidemia?
- Yes. Clin2 currently lists 37 recruiting primary hypercholesterolemia or mixed hyperlipidemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary hypercholesterolemia or mixed hyperlipidemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary hypercholesterolemia or mixed hyperlipidemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.