Clinical trials
Procedural Pain clinical trials
Below are recruiting procedural pain clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07732764Recruiting
TENS for Pain After Chest Surgery
This trial tests if a mild electrical therapy (TENS) can reduce pain after chest surgery. It may help you need less pain medicine and feel better during recovery.
Kaohsiung City, Kaohsiung CityAges 15–85 - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT06731647RecruitingPhase 2
Anti-inflammatory drugs for pleurodesis in pneumothorax
This trial tests whether using non-steroidal anti-inflammatory drugs (NSAIDs) during pleurodesis (a procedure to seal the lung lining) helps people with a collapsed lung (pneumothorax). It aims to see if these drugs can improve outcomes.
AmiensAges 18 years+ - NCT07172984Recruiting
Can breathing exercises help during joint injections?
This study tests whether paying attention to your breathing during an ultrasound-guided joint injection helps you feel more comfortable. It could make the procedure easier for you.
ChambéryAges 18 years+ - NCT07021105Enrolling by invitation
Comparing nerve blocks for pain after gynecological surgery
This study tests two different types of nerve blocks (called 'plain blocks') to see which one works better for controlling pain after major gynecological surgery. You would receive one of the blocks before surgery, and then use a pump you control to get extra pain medicine as needed.
Adana, SarıçamAges 18–69 - NCT07542730RecruitingPhase 4
Diphenhydramine to ease discomfort during early abortion procedure
This study tests whether adding diphenhydramine (a common allergy medicine) to sedation helps patients feel more comfortable during a procedural abortion in the first trimester. Researchers want to see if it improves pain control and overall experience.
Rochester, New YorkAges 18 years+ - NCT07062497RecruitingPhase 2/Phase 3
Clonidine in nerve block for umbilical hernia repair
This trial tests if adding clonidine to a numbing injection (nerve block) improves pain control after outpatient umbilical hernia repair. It aims to reduce the need for pain medicines and enhance recovery.
Rio de Janeiro, Rio de JaneiroAges 18–65 - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT06785389Recruiting
How fear before surgery affects pain and recovery
This study looks at how feeling scared or anxious before surgery might affect your pain and recovery afterward. It aims to help improve care for future patients.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06745453Recruiting
Nerve block for back pain in the ER
This trial tests whether a numbing injection near your spine can quickly relieve sudden back pain that has lasted less than six weeks. If it works, it could be a fast, non-opioid option during an ER visit.
Chicago, IllinoisAges 18 years+ - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80 - NCT07417839Recruiting
Toy nebulizer vs distraction cards for children's fear during breathing treatment
This study compares using a toy-shaped nebulizer or distraction cards to reduce fear in children aged 3-6 who are receiving their first breathing treatment for asthma or bronchitis. It aims to see which method makes the experience less scary and increases parent satisfaction.
Baghdad, MouslAges 3–6 - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Baltimore, MarylandAges 18 years+ - NCT05744024Enrolling by invitation
VR-based comfort care during complex wound procedures
This trial studies a non-medicine way to reduce pain during complex wound care, possibly using VR or similar distraction tools. You may be able to join if you have painful wound procedures and can safely use the VR setup.
Amsterdam, North HollandAges 18 years+ - NCT07718477Recruiting
Comparing child and parent pain during dental numbing
This study compares the pain a child feels during a numbing injection at the dentist to the pain the parent thinks the child is feeling. It helps doctors understand the difference between a child's actual pain and what parents perceive, which may improve how pain is managed during dental visits.
Clermont-FerrandAges 6–15 - NCT07577869Recruiting
Nerve blocks for pain relief after knee replacement
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Kayseri, KocasinanAges 18–80 - NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT07174440Recruiting
Testing numbing medicine for spine surgery
This trial is testing a numbing medicine placed near the spine (erector spinae block) during lumbar spine fusion surgery. It aims to see if it helps control pain and may reduce the amount of anesthetic needed during the procedure.
Cleveland, OhioAges 21–75 - NCT04219956Recruiting
Low-sugar diet aims to reduce belly-surgery pain
This study tests whether a special diet low in polyamines (a food-related substance) can reduce pain after major abdominal surgery. It compares pain control while you use a patient-controlled morphine pump or take opioid tablets by mouth after surgery.
BrestAges 18 years+ - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07234396Recruiting
Animated video for kids having elbow pins removed
This trial tests whether watching a short animated video before getting metal pins removed from a broken elbow can help reduce pain and anxiety in children. It compares the video to the usual care, which is just talking to the child.
Karachi, SindhAges 4–12 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT05779852Recruiting
Hypnosis to ease new foot amputation wound pain
This trial tests whether auto-hypnosis (a self-guided calming technique) can reduce pain after a toe or multiple toes are removed. It is for adults who are newly after an amputation and have moderate pain soon after the first dressing.
RennesAges 18 years+
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Common questions
- Are there clinical trials for procedural pain?
- Yes. Clin2 currently lists 82 recruiting procedural pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a procedural pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a procedural pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.