Clinical trials
Prostate Cancer Surgery clinical trials
Below are recruiting prostate cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07071207Recruiting
Text reminders after prostate surgery
This trial tests if text message reminders help men recover urinary control after prostate surgery. If you are planning prostate surgery and can use a mobile phone for texts, you may be able to join.
Rochester, New YorkAges 18 years+ - NCT07038304RecruitingPhase 2
Radiation for cancer growth in prostate cancer that stopped responding to hormones
This trial tests whether giving precise radiation to a few spots of cancer growth can help control prostate cancer that has stopped responding to hormone therapy. It is for people with up to 3 growing or new spots of cancer on a special scan.
GroningenAges 18 years+ - NCT07028853RecruitingPhase 3
New drug combo for advanced prostate cancer
This study tests whether adding the investigational drug mevrometostat to the standard treatment enzalutamide works better than enzalutamide alone for men with prostate cancer that has spread to other parts of the body (metastatic castration-sensitive prostate cancer). You may benefit if you haven't yet received chemotherapy or similar strong treatments for this stage of cancer.
Huntsville, AlabamaAges 18 years+ - NCT07027124RecruitingPhase 2
High-risk prostate cancer treatment before and after surgery
This trial tests a combination of hormone therapy, a targeted pill (Darolutamide), and an immunotherapy drug (Pembrolizumab) before and after surgery for men with high-risk prostate cancer that has specific genetic features. The goal is to see if this approach helps prevent the cancer from coming back.
New York, New YorkAges 18 years+ - NCT05805436RecruitingPhase 4
Laxatives before robotic prostate or kidney surgery
This trial tests whether giving a laxative before certain robotic urologic surgeries improves bowel function after surgery. It may help reduce constipation and related discomfort during recovery.
Iowa City, IowaAges 30–100 - NCT07005154RecruitingPhase 2
Study of ASP5541 for metastatic prostate cancer
This study tests an experimental drug called ASP5541 for men with metastatic prostate cancer (either hormone-sensitive or castration-resistant). It aims to see if the drug can slow cancer growth and improve outcomes when added to standard hormone therapy.
Huntsville, AlabamaAges 18 years+ - NCT07001709RecruitingPhase 4
How abiraterone affects oxycodone in prostate cancer
This study looks at how a common prostate cancer drug (abiraterone) affects how the body processes a painkiller (oxycodone). Men with prostate cancer who take abiraterone will be compared with those who do not, to see if the painkiller works differently.
Deventer, OverijsselAges 18 years+ - NCT05740956RecruitingPhase 1
Drug study for cancers with HRR gene or HRD changes
This Phase 1 study tests HS-10502 in people with advanced solid tumors that have certain DNA repair problems (HRR or HRD). It may help by finding a safe dose and seeing whether the drug can shrink tumors in cancers that have specific genetic features.
Beijing, Beijing MunicipalityAges 18–75 - NCT06970275Recruiting
PET-CT imaging study for cancer surgery patients
This trial uses a special PET-CT scanner to take high-resolution images of cancer tumors that have been surgically removed. The goal is to see how well these images match the results from standard lab tests, such as pathology, and to track long-term outcomes.
AalstAges 18 years+ - NCT06970119RecruitingPhase 1/Phase 2
Study of INR102 for advanced prostate cancer (Phase 1/2)
This trial tests a new investigational drug called INR102 for prostate cancer that has spread and stopped responding to standard treatments. It's given by injection, and the study will check if it's safe and if it can shrink or slow the cancer.
Wuxi, JiangsuAges 18 years+ - NCT06684652Recruiting
Comparing targeted plus standard biopsies for prostate cancer diagnosis
This trial tests whether adding a targeted biopsy to a standard sextant biopsy improves the detection of prostate cancer. It is for men aged 45 to 85 who have a suspicious spot on an MRI of their prostate and have not had a biopsy before.
Beijing, Beijing MunicipalityAges 45–85 - NCT06940271Recruiting
Nerve wrap procedure during prostate surgery to help preserve erectile function
This study tests wrapping the nerves next to the prostate with a special tissue graft during prostate cancer surgery. The goal is to see if it helps keep erectile function after surgery.
Jacksonville, FloridaAges 45 years+ - NCT06915909Recruiting
Robotic prostate surgery with low pressure gas for less pain
This trial tests whether using lower gas pressure during robotic prostate surgery can reduce pain after the operation. It aims to help men recover more comfortably.
Stevenage, HertfordshireAges 18–75 - NCT04004312Recruiting
Short-course radiation slices for localized prostate cancer
This trial tests a radiation approach that delivers treatment in a small number of larger “fractions” (short-course SBRT) for prostate cancer. It may help by targeting the prostate while shortening the overall number of visits.
Montreal, QuebecAges 18 years+ - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT06392737Recruiting
AI-guided MRI vs routine MRI for prostate biopsy
This study tests whether an artificial intelligence tool for MRI can improve the results of targeted prostate biopsy, compared to the usual method. It could help diagnose prostate cancer more accurately with fewer needles.
Beijing, Beijing MunicipalityAges 45–85 - NCT06864533Recruiting
Chemotherapy after surgery for aggressive prostate cancer
This trial tests whether adding chemotherapy after standard treatment helps people with a very aggressive type of prostate cancer (Gleason score 9-10). It is designed for those who have not had their cancer spread to distant parts of the body and are healthy enough to handle chemotherapy.
Beijing, Beijing MunicipalityAges 18–80 - NCT06776172Recruiting
Lymph node removal during prostate surgery: a comparison study
This trial tests whether removing pelvic lymph nodes during prostate cancer surgery improves outcomes for men with high-risk prostate cancer. If you have high-risk prostate cancer and no signs of spread, you may be able to join.
AarauAges 18 years+ - NCT06854250RecruitingPhase 2
Cryoablation and low-dose chemo for metastatic prostate cancer
This trial tests freezing prostate tumors (cryoablation) combined with a low-dose chemotherapy pill (metronomic cyclophosphamide) for men with metastatic prostate cancer. The goal is to see if this combination can slow the cancer's growth and improve outcomes.
Guangzhou, GuangdongAges 18–80 - NCT06822452Recruiting
Outpatient vs. inpatient robotic prostate removal study
This study compares recovery experiences for men having robot-assisted prostate removal surgery as an outpatient (going home the same day) versus staying overnight in the hospital. It looks at early complications to see which approach might work better for eligible patients.
AvignonAges 18 years+ - NCT06835218Recruiting
Prostate cancer real-world evidence registry
This study collects information from men with prostate cancer to better understand how different treatments work in real life. It follows patients when they start a new treatment and can help improve future care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06822036Recruiting
Starch powder to reduce bleeding in prostate surgery
This trial tests whether applying a dissolvable starch powder (Arister) inside the pelvis during robot-assisted prostate cancer surgery reduces post-surgery bleeding. It is for men whose surgeons plan to spare the nerves controlling erections and who have moderate erectile function beforehand.
Hamburg, Free and Hanseatic City of HamburgAges 45–68 - NCT06801236RecruitingPhase 1
A new drug for advanced prostate cancer that has stopped responding to treatment
This early-phase trial tests a new study drug called ACE-232 for men with advanced prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It aims to see if the drug is safe and may help slow the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06220435Recruiting
Radiation therapy for very high-risk localized prostate cancer
This trial tests radiation therapy for men with very high-risk prostate cancer that hasn't spread. It aims to see if targeting the tumor with radiation can help control the cancer in this highest risk group.
LundAges 18 years+
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Common questions
- Are there clinical trials for prostate cancer surgery?
- Yes. Clin2 currently lists 463 recruiting prostate cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.