Clinical trials
Radiation Therapy clinical trials
Below are recruiting radiation therapy clinical trials, each written for real people, not researchers. We’re tracking 675 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07070076Recruiting
Y-90 therapy vs chemo infusion for liver cancer
This study compares two liver-directed treatments—radioactive Yttrium-90 beads (SIRT) and a type of chemo infusion directly into the liver (HAIC)—for people whose liver cancer is advanced enough to need treatment but might still be removable with surgery. The goal is to see which approach can shrink the tumor best before surgery.
Guangzhou, GuangdongAges 18–75 - NCT04888338Recruiting
Studying outcomes after CAR-T, radiation, or bispecific therapy
This study looks at how people with blood cancers do after they receive CAR-T therapy, radiation therapy, and/or bispecific therapy. It may help doctors understand which treatment combinations work best and what side effects to expect.
Houston, TexasAges 18 years+ - NCT01255748Recruiting
Registry study tracking outcomes after radiation treatment
This registry study collects information from people who are planning to receive radiation therapy. The goal is to better understand treatment outcomes and help improve radiation care over time.
Scottsdale, ArizonaAges Any age - NCT04787744RecruitingPhase 2/Phase 3
Test standard prostate cancer treatment with or without targeted spot radiation
This study tests whether adding targeted local treatment (like radiation to a few spots seen on scans) improves outcomes for some people with limited (oligometastatic) prostate cancer. It compares standard systemic therapy alone versus standard therapy plus PET-scan–guided spot treatment.
Long Beach, CaliforniaAges 18 years+ - NCT01492972RecruitingPhase 3
Lighter radiation, with or without hormone suppression
This Phase 3 trial tests whether giving a smaller amount of radiation (“hypo-fractionated” means fewer, larger sessions) can work as well as standard approaches for intermediate-risk prostate cancer. It also compares adding hormone therapy (“androgen suppression”) to radiation versus using radiation alone.
Scottsdale, ArizonaAges 18 years+ - NCT07074470Recruiting
New drug combo for relapsed brain lymphoma
This trial tests a new combination of drugs (teniposide, a PD-1 checkpoint inhibitor, and selinexor) for people with relapsed or refractory primary central nervous system lymphoma. It aims to see if this three-drug approach can shrink tumors or slow the disease when previous treatments haven't worked.
Suzhou, JiangsuAges 18–75 - NCT03546829RecruitingPhase 1
Testing targeted radiation plus short anti-microbial treatment
This early safety study tests a combination of focused radiation and a targeted anti-microbial (antibiotic/antifungal/antiviral/anti-parasite) plan for certain lung cancer that is starting to progress in a few spots. It aims to see whether this approach is safe and helps control the small areas of progressing cancer after prior treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06826885Recruiting
Comparing two types of radiation for breast cancer
This trial is testing how well two different radiation techniques, IMPT and IMRT, work for treating breast cancer. It aims to see which one is safer and more effective, so you might benefit from a potentially better treatment approach.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06889649RecruitingPhase 2
SBRT plus immunotherapy and targeted therapy for kidney cancer
This trial tests a combination of targeted therapy (axitinib) and immunotherapy (toripalimab) alongside stereotactic body radiation therapy (SBRT) for kidney cancer that has come back or spread. It may be an option if you have a limited number of metastatic tumors that can be treated with radiation.
Beijing, Beijing MunicipalityAges 18–80 - NCT06954831RecruitingPhase 2
Short-course radiation for early-stage breast cancer
This trial tests a shorter, more intense radiation schedule for people with stage I-III breast cancer after lumpectomy. It aims to find if giving a higher daily dose over fewer sessions is safe and effective.
Arcadia, CaliforniaAges 40 years+ - NCT04846309RecruitingPhase 1
MRI scan to personalize radiation for esophageal cancer
This Phase 1 study uses specialized imaging (including MRI) to better “see” low-oxygen areas in esophageal cancer and help guide individualized radiation treatment. It aims to improve how radiation is planned and delivered while checking safety.
Salt Lake City, UtahAges 18 years+ - NCT05301283RecruitingPhase 2
Adaptive radiation therapy before surgery for soft-tissue sarcoma
This trial tests a personalized (“adaptive”) radiation plan before surgery for high-grade soft-tissue sarcoma that can be removed. It may help shrink the tumor and improve how well surgery can treat the cancer.
Tampa, FloridaAges 18 years+ - NCT01985984Recruiting
Predicting outcomes after head and neck radiotherapy
This study looks at how outcomes may be predicted for people with head and neck cancer who receive radiotherapy. It may help doctors better estimate results and tailor follow-up care.
MaastrichtAges 18 years+ - NCT06305715RecruitingPhase 2
Radiation before targeted therapy for advanced lung cancer
This trial tests if giving radiation to the main lung tumor before starting a targeted therapy pill can help delay the cancer from growing. It is for people with advanced non-small cell lung cancer that has a specific genetic change and who have not had targeted therapy before.
Milwaukee, WisconsinAges 18 years+ - NCT06461793RecruitingPhase 2
Higher dose radiation with hormone therapy for high-risk prostate cancer
This trial tests a higher dose of radiation given in fewer sessions (hypofractionated) combined with hormone therapy for men with high-risk prostate cancer that has not spread. A gel spacer called SpaceOAR is used to protect the rectum. The goal is to see if this approach is safe and effective.
SeoulAges 20 years+ - NCT07575815Recruiting
Understanding Anxiety in Children During Radiation Therapy
This study watches how children feel anxious before and during radiation therapy treatment at MD Anderson. By understanding anxiety patterns, doctors hope to better support children and families going through this experience.
Houston, TexasAges 2–12 - NCT07237269RecruitingPhase 2
Abiraterone/prednisone plus ADT for early prostate cancer
This trial tests adding abiraterone (a hormone therapy pill) and prednisone to standard hormone therapy (ADT) for prostate cancer that has spread to nearby lymph nodes but is too small to see on regular scans. The goal is to see if this combination works better than ADT alone.
Omaha, NebraskaAges 30 years+ - NCT06630793Recruiting
Comparing types of radiation for anal cancer
This study compares standard radiation (IMRT) with a newer, more precise type (IMPT) both given alongside chemotherapy for anal cancer. It aims to see which is better at controlling cancer and reducing side effects.
Mumbai, MaharashtraAges 18–80 - NCT06927635RecruitingPhase 2
SBRT vs standard care for prostate cancer that has spread to a few spots
This trial tests whether targeted radiation (SBRT) to a few sites of cancer spread can help men whose prostate cancer has stopped responding to hormone therapy but has not spread to many places. You may benefit if you have a limited number of growing spots outside the brain or spine.
Toronto, OntarioAges 18–100 - NCT06909201Recruiting
Lung MRI scan to study radiation treatment effects
This study uses a special MRI scan with xenon gas to see how radiation therapy affects your lungs. It may help doctors better understand treatment response and side effects.
Houston, TexasAges 18 years+ - NCT05805371RecruitingPhase 1
PSCA CAR-T cells with or without radiation for prostate cancer
This Phase 1 study tests a prostate cancer treatment made of PSCA-targeted CAR-T cells, with or without radiation, to help control advanced prostate cancer. It aims to find a safe treatment approach and see how well it works in people whose cancer has PSCA.
Duarte, CaliforniaAges 18 years+ - NCT05327686RecruitingPhase 2
Adding focused radiation to immunotherapy for kidney cancer
This Phase 2 trial studies whether adding focused, high-precision radiation to immunotherapy helps people with advanced kidney cancer (that cannot be removed by surgery or has spread). It aims to improve cancer control by combining two treatment approaches.
Birmingham, AlabamaAges 18 years+ - NCT04589624RecruitingPhase 1
MRI scan to monitor response in head and neck cancers
This Phase 1 study tests an investigational MRI scan (hpMRI) to help doctors see how thyroid cancer and other head-and-neck cancers respond to treatment like radiation or other medicines. If you’re eligible, the scan may help track treatment effects more closely, though it’s still being studied for this purpose.
Houston, TexasAges 18 years+ - NCT03286335Recruiting
Proton radiation for slow-growing or benign brain tumors
This trial studies proton radiation therapy for adults with certain benign or slow-growing brain tumors. It aims to see how well tumors can be controlled, and how treatment affects quality of life and side effects.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for radiation therapy?
- Yes. Clin2 currently lists 675 recruiting radiation therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.