Clinical trials
Radiation clinical trials
Below are recruiting radiation clinical trials, each written for real people, not researchers. We’re tracking 1,030 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04567771Recruiting
Proton vs IMRT radiation after surgery for uterine or cervical cancer
This study compares two types of radiation therapy (proton and IMRT) given after surgery for endometrial or cervical cancer. It aims to see which treatment is better at reducing side effects while still being effective.
Scottsdale, ArizonaAges 18 years+ - NCT04545957Recruiting
Radiation planning study using MRI for adults with cancer
This trial tests a “master protocol” approach to use MRI (a detailed body scan) to help plan radiation treatment for people with cancer. It may help doctors customize radiation more accurately, depending on your specific cancer type.
Boston, MassachusettsAges 18 years+ - NCT04525989Recruiting
Short-course proton vs photon radiation before rectal surgery
This study compares two types of pre-surgery radiation—protons versus standard photons—in people with high-risk rectal cancer. The goal is to shrink and control the tumor while safely getting you ready for surgery, and to see which approach works better.
Stockholm, SolnaAges 18 years+ - NCT03546829RecruitingPhase 1
Testing targeted radiation plus short anti-microbial treatment
This early safety study tests a combination of focused radiation and a targeted anti-microbial (antibiotic/antifungal/antiviral/anti-parasite) plan for certain lung cancer that is starting to progress in a few spots. It aims to see whether this approach is safe and helps control the small areas of progressing cancer after prior treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04402151RecruitingPhase 2
PSMA scan–guided targeted radiation for higher-risk prostate cancer
This trial uses a special PET/MR scan to help doctors aim stereotactic radiation more precisely for certain higher-risk or unfavorable intermediate prostate cancers. It studies whether this targeted approach can safely treat the prostate (and specific areas needing extra treatment) without spreading to the body.
New York, New YorkAges 21–90 - NCT04318717RecruitingPhase 2
Pembrolizumab plus radiation for resected mucosal melanoma
This trial studies whether giving pembrolizumab (an immunotherapy) together with a targeted form of radiation can help after surgery for mucosal melanoma. It aims to lower the chance of the cancer coming back and improve outcomes in people whose tumor was removed.
St Louis, MissouriAges 16 years+ - NCT04151940Recruiting
PET/CT scan changes during chemo with immune therapy
This study looks at how PET/CT scan results change while you receive chemo plus an immune therapy (a PD-1/PD-L1 medicine) for stage IV lung cancer. The goal is to better understand what the scans mean during treatment, which may help guide care in the future.
Seattle, WashingtonAges 18 years+ - NCT04169763RecruitingPhase 1
Nelfinavir with chemo and radiation for vulvar cancer
This Phase 1 trial tests whether adding nelfinavir to standard chemo (cisplatin) and external-beam radiation can treat locally advanced vulvar cancer that cannot be removed with surgery. It’s designed to check safety and how well the treatment can work for this situation.
Houston, TexasAges 18 years+ - NCT04219202Recruiting
Pre-surgery radiation for retroperitoneal soft tissue cancer
This study tests giving special radiation (ions) before surgery for a specific cancer in the back of the abdomen (retroperitoneal soft tissue sarcoma). The goal is to shrink or control the tumor so surgery may be safer or more effective.
HeidelbergAges 18 years+ - NCT04234386Recruiting
Short-course targeted radiation for early breast cancer
This trial tests a radiation plan called GammaPod to treat early breast cancer with precise targeting. It may help patients by delivering the treatment in a more focused way, while checking safety and tumor control in the smallest, well-defined cancers.
Baltimore, MarylandAges 45 years+ - NCT04221893Recruiting
Radiation therapy for metastatic gastrointestinal cancers
This trial tests whether adding radiation therapy to your current immunotherapy can help control cancer that has spread in the digestive system. It aims to improve symptoms and possibly slow the cancer's growth.
San Francisco, CaliforniaAges 18 years+ - NCT04068155Recruiting
Radiation device for certain skin cancers you can treat locally
This trial tests a radiation-emitting device placed near the tumor to treat certain malignant skin cancers that can be fully covered. It may help shrink or control the cancer at the skin site where the device is applied.
GrenobleAges 18 years+ - NCT04122456Recruiting
Study of skin DNA repair in day vs night shift workers
This study compares how well your skin repairs DNA damage in people who mainly work day shifts versus night shifts. It may help researchers understand whether shift work affects skin health and how the skin responds over time.
Fairborn, OhioAges 18–40 - NCT04073966Recruiting
MRI markers for memory changes after brain radiation
This study uses MRI scans to look at how radiation treatment for newly diagnosed brain metastases affects thinking and memory. It aims to understand the effects better, which may help guide future treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT03997110Recruiting
Palliative radiation to relieve pain in advanced cervical cancer
This trial looks at giving radiation to shrink or control advanced cervical cancer to help with symptoms, especially pain. It is for people who are not good candidates for full curative treatment and are expected to have limited time, so the goal is comfort rather than cure.
Mumbai, MaharashtraAges 18–75 - NCT03968406RecruitingPhase 1
Talazoparib plus radiation for recurrent gynecologic cancers
This Phase 1 study tests whether the cancer drug talazoparib, combined with radiation, can better control recurrent gynecologic cancers in the pelvis/abdomen. It focuses on patients whose cancer has come back locally enough that radiation can be given, while other disease is not rapidly worsening.
Baltimore, MarylandAges 18 years+ - NCT03942328RecruitingPhase 1/Phase 2
Immune cell vaccine plus checkpoint treatment after liver radiation
This trial tests a combination of a personalized immune cell treatment (made from your own cells) and a pneumococcal vaccine along with an “immune checkpoint” drug after high-dose radiation for certain unresectable liver cancers. The goal is to help your immune system better attack the cancer and to see how safe and effective this approach is.
Rochester, MinnesotaAges 18 years+ - NCT03875716Recruiting
De-intensified radiation after surgery for HPV throat cancer
This trial studies a lower-intensity (less aggressive) course of radiation therapy after curative surgery for HPV-related tonsil or base-of-tongue cancer. The goal is to see if patients can still be treated successfully while reducing side effects from radiation.
Boston, MassachusettsAges 18 years+ - NCT03803787RecruitingPhase 2
Inhaled steroid to prevent lung inflammation during cancer treatment
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Mexico CityAges 18–75 - NCT03726359Recruiting
Targeted radiation for brain metastases using staged stereotactic treatment
This Phase 1 study tests a form of focused radiation given in stages to shrink larger brain metastases. It may help people whose tumors are in the brain but not suited to whole-brain radiation alone, while also checking safety and how well the treatment can be delivered.
The Bronx, New YorkAges 18 years+ - NCT03286335Recruiting
Proton radiation for slow-growing or benign brain tumors
This trial studies proton radiation therapy for adults with certain benign or slow-growing brain tumors. It aims to see how well tumors can be controlled, and how treatment affects quality of life and side effects.
Boston, MassachusettsAges 18 years+ - NCT03161522RecruitingPhase 2
Chemo alone versus with radiation or surgery for limited spread
This study tests whether adding radiation or surgery to chemotherapy can improve outcomes for people whose esophageal or stomach cancer has spread to only a few places. If your cancer is “oligometastatic” (up to 3 spots), the trial helps doctors see which approach gives the best control.
Houston, TexasAges 18–79 - NCT02734537RecruitingPhase 2
Radiation with or without cisplatin after head and neck surgery
This trial studies whether adding cisplatin (a chemotherapy medicine) to radiation therapy helps people with stage III–IVA squamous cell cancer of the head and neck after they’ve had surgery. It’s meant to lower the risk of the cancer coming back.
Birmingham, AlabamaAges 18 years+
Hear when a new Radiation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for radiation?
- Yes. Clin2 currently lists 1,030 recruiting radiation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.