Clinical trials
Regurgitation clinical trials
Below are recruiting regurgitation clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05021614Recruiting
Valveclip repair study for leaking mitral valve in older adults
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
SichuanAges 60 years+ - NCT06162780Recruiting
Clip repair for severe mitral valve leak
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
Guangzhou, GuangdongAges 18 years+ - NCT05114850Recruiting
Follow-up study for people treated with TricValve
This study looks back at patients who were successfully treated with TricValve bicaval valve devices and then follows up with their outcomes. You might join if you (or your legal guardian) agree to be included.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT07796659Recruiting
Early study of a new implant for leaking heart valve
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
TbilisiAges 18 years+ - NCT06595992Recruiting
Observing moderate aortic valve disease over time
This study follows people with moderate aortic valve disease to learn how their condition changes. It does not test a new treatment but will help doctors better understand the disease.
Hangzhou, ZhejiangAges 18 years+ - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT04888247Recruiting
Testing a new mitral valve replacement for high-risk patients
This study checks whether an innovative device can safely replace a damaged mitral valve in people who are higher risk for open-heart surgery. It looks at how well the procedure and follow-up work for improving mitral leakage symptoms.
AuchenflowerAges 18 years+ - NCT07726173Recruiting
Off-pump mitral valve repair through the heart
This trial tests a new way to repair a leaky mitral valve without stopping the heart or using a heart-lung machine. The surgery is done through a small cut in the heart's lower chamber. It may be an option for people with severe degenerative mitral regurgitation who are not good candidates for standard open-heart surgery.
Baltimore, MarylandAges 21 years+ - NCT06643325Recruiting
Gastric emptying after traumatic injuries
This study looks at how quickly the stomach empties after a traumatic injury. It may help doctors understand digestion in injured patients.
WinterthurAges 18 years+ - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT03692598Recruiting
Transcatheter repair for leaky tricuspid valve during heart surgery
This trial studies a catheter-based repair to help fix a leaky tricuspid valve (regurgitation), especially when you’re also having another heart surgery. It aims to improve valve function and symptoms while tracking safety and outcomes.
AarhusAges 18–85 - NCT07655505Recruiting
Robotic mitral valve repair with force feedback tools
This trial tests a new robotic tool that gives surgeons a sense of touch during mitral valve repair. If you have a severe leak in your mitral valve and are a good candidate for minimally invasive surgery, this study may offer a way to fix it using the da Vinci robot.
Atlanta, GeorgiaAges 22 years+ - NCT07624383Recruiting
New topical treatment for nonerosive acid reflux disease
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07605715Recruiting
Catheter vs. Surgery for Leaky Mitral Valve
This study compares two ways to fix a leaky mitral valve (a heart valve that doesn't close properly): one using a thin tube inserted through blood vessels (catheter) versus traditional open-heart surgery. The goal is to see which approach works better and is safer for older adults.
Los Angeles, CaliforniaAges 60 years+ - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT07586995Recruiting
Safety and performance study of the TriClip heart valve repair device
This study tracks how well the TriClip device works and how safe it is after it's placed in your heart to repair a leaky valve. You'll attend follow-up visits so doctors can monitor your recovery and device function over time.
Phoenix, ArizonaAges 18 years+ - NCT07534917Recruiting
New Pacemakers and Heart Function Study
This study compares newer pacemaker types to see how well they work and how they affect your heart's pumping ability and valve function over a short period. You'll be monitored closely with heart imaging to understand which pacemaker performs best.
LondonAges 18 years+ - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT07509658Recruiting
TriClip device safety and performance study in Japan
This study will track how well the TriClip device works and its safety in people who are already eligible to receive it under its approved use. It helps make sure the device performs as expected in real-world patients.
Suita, OsakaAges Any age - NCT07516145Recruiting
Robotic catheter repair for leaky tricuspid heart valve
This trial tests a new robotic catheter procedure to repair a leaky tricuspid valve (the valve on the right side of your heart). Instead of open-heart surgery, doctors thread a tiny device through a vein in your neck to fix the valve. It may be an option if you have severe leaking and your heart team thinks surgery is too risky for you.
ShatinAges 18–90 - NCT07503236Recruiting
Study of a new device for leaking heart valves
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
Sacramento, CaliforniaAges 21 years+ - NCT07501234Recruiting
Study of the MitraFix® mitral valve repair system
This trial tests a new catheter-based device to fix a leaky mitral valve without open-heart surgery. It is for people whose severe mitral regurgitation puts them at high risk for traditional surgery.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for regurgitation?
- Yes. Clin2 currently lists 200 recruiting regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.