Renal Artery Stenosis clinical trials

Stent decisions for kidney artery narrowing in hard-to-control blood pressure

This trial studies whether using a pressure-based test called fractional flow reserve (FFR) helps doctors choose the right kidney artery stent for people with narrowing of kidney arteries and high blood pressure. It may help improve blood pressure control while avoiding unnecessary procedures.

Stent vs. medication for narrowed kidney artery

This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.

Stenting narrowed kidney artery to help high-risk patients

This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.

Treating narrowed arteries in transplanted kidneys

This trial tests a treatment for a condition that can happen after a kidney transplant, where the artery to the new kidney becomes narrowed. If you have been told you have this problem, the study may help find the best way to treat it.

Blood Vessel Problems After Kidney Transplant Treatment

This study looks at treating narrowing or blockage of blood vessels in transplanted kidneys. If your transplanted kidney is showing signs of not working well and imaging shows a blocked vessel, this trial tests whether a procedure called angioplasty (opening the vessel with a tiny balloon) can help restore blood flow and improve kidney function.

Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis

Comparing two treatments for narrowed neck arteries

This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.

Ultrasound of kidney arteries in ICU patients with kidney injury

This study uses an ultrasound test to check the blood flow to your kidneys soon after you enter the ICU. It aims to see if this test can help doctors better understand and treat acute kidney injury in critically ill patients.

Testing a paclitaxel-coated balloon for leg artery disease

This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.

Kidney artery fibromuscular dysplasia registry for patients

This registry collects information from people diagnosed with kidney artery fibromuscular dysplasia (or certain similar, “atypical” cases). It helps doctors better understand patterns of the condition and may guide future research and care.

Test heart blood-flow measurements before and after TAVI

This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.

Carotid stenting for high-risk carotid surgery patients

This trial tests whether placing a stent in the narrowed carotid artery is a good option for people who are at high risk for the standard surgery (carotid endarterectomy). If you have significant blockages in your neck arteries and certain health or anatomical factors that make surgery riskier, this study may be for you.

Optimized kidney nerve treatment for high blood pressure

This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.

Shunt for carotid artery narrowing

This study tests a new device that is placed through the carotid artery in the neck to temporarily block blood flow during a procedure to open up a narrowed carotid artery. It might be an option for people who have high-risk features that make traditional surgery more challenging.

Stent-like device for blocked leg arteries in the thigh or knee

This trial studies a new stent-like vascular scaffold to improve blood flow in people with symptomatic blockage in the thigh/knee artery. It may help reduce symptoms from narrowed or blocked arteries, but you must meet several artery and health requirements.

Study of a new shunt system for carotid artery blockage treatment

This trial tests a special shunt system to protect your brain during carotid artery stenting. It may help people with severe blockages in the neck artery that supplies blood to the brain.

Kidney nerve block for high blood pressure during surgery

This trial tests if numbing the nerves around the kidney artery during laparoscopic surgery can better control high blood pressure. It is for people already needing surgery for certain kidney or adrenal conditions who also have hypertension.

Tirofiban for recent mild stroke or TIA with narrowed brain artery

This trial tests the drug tirofiban (a blood thinner) to prevent another stroke in people who have had a mild stroke or high-risk TIA and have a narrowed artery in the brain. It must be started within 24 hours of symptoms.

Arm vs. Leg Artery for Carotid Stenting

This study compares two ways to reach the blocked neck artery during a stent procedure: through an artery in your arm versus one in your groin. The goal is to see which route is safer and works better for patients who need this treatment.

Rapamycin-coated stent for narrowed brain arteries

This study tests a special stent that slowly releases a drug (rapamycin) to keep a narrowed brain artery open. It is for patients who have had strokes despite medical treatment.

Renal denervation for young women with high blood pressure

This study tests a procedure called renal denervation to help lower blood pressure in young women with high blood pressure that’s not too severe. The goal is to see if the treatment can improve blood pressure control safely.

Staged heart bypass plus TAVR versus TAVR alone

This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.

Compare procedures to improve heart blood flow in diabetes

This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.

Testing a drug-coated balloon for small heart arteries

This study tests a drug-coated balloon (DCB) that releases two medicines (sirolimus and paclitaxel) to open blocked small heart arteries. It may help people with stable chest pain or recent, controlled heart events who have a narrowed small vessel.