Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07270068Recruiting
Diabetes remission through lifestyle change for Malaysian patients
This study tests whether a lifestyle program can help Malaysian adults with recently diagnosed type 2 diabetes and overweight or obesity achieve remission of their diabetes. If you qualify, you’ll get support to change your diet and activity habits.
Seremban, Negeri SembilamAges 18–70 - NCT06891807Recruiting
Robotic vs augmented reality knee replacement
This study compares two advanced technologies for total knee replacement: a robot that uses a CT scan for guidance versus an augmented reality system that uses no scan. The goal is to see which approach leads to better outcomes for patients with osteoarthritis.
Sint-Martens-Latem, Oost-VlaanderenAges 18–85 - NCT06758297Recruiting
AI motivational talk after knee replacement
This study tests whether an artificial intelligence-guided motivational conversation can help reduce fear of moving after knee replacement surgery, and improve how much you can move.
Samsun, SamsunAges 18 years+ - NCT06518317RecruitingPhase 3
Short vs Long Blood Thinner Use After TAVI
This trial compares a short course versus a longer course of antiplatelet medicine (blood thinners) after a TAVI procedure for aortic stenosis. It aims to see which approach is safer and more effective.
CaenAges 18 years+ - NCT06896227Recruiting
TAVR positioning and its effect on valve and heart blood flow
This study looks at how the placement of a new aortic valve (TAVR) affects blood flow through the valve and into the heart arteries. It may help doctors understand best practices for people who already had a TAVR procedure.
DüsseldorfAges Any age - NCT05030220Recruiting
Testing testosterone and a skin bacteria during shoulder surgery
This study looks at how testosterone levels and a common skin bacteria (Cutibacterium) may relate to outcomes around elective shoulder replacement surgery. Results could help improve how doctors prevent and understand infection risk or healing after surgery.
Seattle, WashingtonAges 18–89 - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07239817Recruiting
Nerve block and local anesthetic for hip replacement surgery
This study tests whether a nerve block plus local anesthetic can improve pain control during and after hip replacement surgery for a broken hip. It may help reduce the need for stronger pain medications and improve recovery.
MilanAges 18 years+ - NCT07230041Recruiting
Antibiotic removal during kidney therapy in the ICU
This trial studies how much certain antibiotics (meropenem, linezolid, and daptomycin) are removed when you're on a special blood-filtering machine called continuous renal replacement therapy (CRRT) for severe kidney injury. The results could help doctors give the right dose of antibiotics to treat infections effectively.
Milan, ItaliaAges 18 years+ - NCT06908564Recruiting
Game-based balance rehab after hip replacement
This study tests a fun, game-based balance exercise program for people recovering from their first hip replacement. It may help you improve your balance and recover faster.
Rome, ItalyAges 18–85 - NCT05992064Recruiting
Wearable sensors to track recovery after knee replacement
This study uses a small wearable sensor placed on your leg after knee replacement surgery to track your recovery. It helps doctors see how well you are moving and healing, without extra visits to the hospital.
Frederikshavn, North DenmarkAges 18 years+ - NCT07207005Recruiting
Comparing wear in two hip replacement sockets
This study compares how much two different types of dual-mobility hip sockets wear down over time in people having a hip replacement. If you are between 55 and 80 and scheduled for this surgery, you may be eligible to help doctors find out which implant lasts longer.
Lyon, FranceAges 55–80 - NCT06932718Recruiting
Smoking cessation program for Hong Kong workers
This study tests a workplace program to help people in Hong Kong quit smoking. It includes support through instant messaging and check-ins over 12 months.
Hong KongAges 18 years+ - NCT07199751Recruiting
Fast-track vs standard recovery after hip replacement
This study compares two recovery methods after hip replacement: standard care versus a fast-track program. The goal is to see which approach leads to fewer complications, better function, and improved quality of life.
MünchenAges 18 years+ - NCT05062239Recruiting
Statin use after valve surgery to prevent heart rhythm trouble
This study looks at whether taking statin medicines around the time of surgical aortic valve replacement can lower the chance of a common post-surgery heart rhythm problem called atrial fibrillation. It also compares statin-related factors in people who are at the time of surgery in normal rhythm and not on strong rhythm-stabilizing medicines.
OdenseAges 60–95 - NCT07187440Recruiting
Study of Fabry disease treatment in Chinese children and adults
This study tests an enzyme replacement therapy (agalsidase alfa) for Fabry disease in Chinese children and adults. It's an observational study that follows patients who receive the treatment as part of their regular care.
Hefei, AnhuiAges 7 years+ - NCT07191262Recruiting
Comparing mouth rinses after tooth extraction and bone graft
This study compares three different mouth rinses (one with EDTA, one with chlorhexidine, and one with essential oils) after tooth extraction and bone grafting. It aims to find which rinse helps keep the area clean and promotes healing.
Birmingham, AlabamaAges 18–85 - NCT07183475Recruiting
Returning to sports after knee replacement
This study looks at how well people can get back to sports after having a knee replacement. If you have had a knee replacement and are active in sports, you may be able to join to help researchers learn more about recovery.
Munich, BavariaAges 18–85 - NCT07178223Recruiting
Thumb base replacement surgery for arthritis
This study tests a new type of thumb joint replacement surgery for people with arthritis at the base of the thumb. The goal is to see if it relieves pain and improves function better than current treatments.
StockholmAges Any age - NCT07173855RecruitingPhase 4
Magnesium replacement in ICU patients
This trial tests whether giving magnesium as part of a standard hospital protocol can lower the risk of irregular heartbeat and improve survival in patients admitted to the intensive care unit.
Ajax, OntarioAges 16 years+ - NCT04705896RecruitingPhase 4
Albumin for kidney recovery after ICU kidney injury
This trial tests whether giving albumin (a blood protein through an IV) can improve recovery after acute kidney injury in people who are in the ICU and need kidney support treatment. It mainly aims to help the kidneys bounce back better after this serious illness.
Calgary, AlbertaAges 18 years+ - NCT07160075RecruitingPhase 4
HIV prevention with PrEP for people on opioid therapy
This trial tests if daily PrEP medication can help prevent HIV in people receiving opioid replacement therapy. You must be HIV-negative and regularly attend your opioid treatment program to join.
Calgary, AlbertaAges 16 years+ - NCT07155837Enrolling by invitation
TENS for pain after first knee replacement surgery
This study tests if a TENS device, which uses mild electrical pulses to relieve pain, helps people recover better after their first total knee replacement. It might reduce pain and improve movement.
Adana, AdanaAges 18 years+
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 507 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.