Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06001333Recruiting
Fecal transplant to clear superbugs from the gut
This study tests whether a fecal transplant (FMT) can remove certain antibiotic-resistant bacteria from your gut. It might help people who carry superbugs like CPE or VRE but aren't currently on antibiotics.
Chuncheon, Gangwon-doAges 20 years+ - NCT03522545RecruitingPhase 1
Stem cell add-on for hard-to-treat bipolar depression
This Phase 1 study tests whether adding allogeneic (donor) stem cells to standard care is safe and may help adults with bipolar depression that has not improved with usual treatments. It mainly targets people with more severe symptoms and certain blood inflammation levels.
Houston, TexasAges 18–65 - NCT05871476Recruiting
Study to reduce resistant bacteria spread in young children
This study tests ways to reduce how a hard-to-treat bacterial germ spreads between hospitals, homes, communities, and animals. It focuses on children under 2 years old in the selected hospital area because they may be more likely to pick up and spread the bacteria.
Thái Bình, Thai BinhAges Up to 2 years - NCT06557720Recruiting
Imaging study for hard-to-control epilepsy
This study looks at how different brain scans (like MRI, PET, and EEG) can help find the exact spot where seizures start in people whose epilepsy hasn't been controlled by medicines. It aims to better understand drug-resistant epilepsy so doctors can plan more accurate treatments.
Xi'anAges 18–65 - NCT06895863Recruiting
Personalized magnetic brain therapy for hard to treat depression
This study tests a new way to use magnetic brain stimulation tailored to each patient to treat depression that hasn't improved with at least two different medications. It may help people who are still struggling with moderate to severe depression.
Glostrup MunicipalityAges 18–95 - NCT06885736Recruiting
Preserving muscle with exercise and protein on weight loss drugs
This trial tests whether adding resistance exercise and extra protein can help you keep your muscle while taking weight loss medications like semaglutide or tirzepatide. It is for people with a BMI of 27 or higher who are not already exercising regularly.
Kuwait CityAges 18 years+ - NCT06863272RecruitingPhase 1/Phase 2
Study of ifinatamab deruxtecan for advanced prostate cancer
This trial tests a new drug, ifinatamab deruxtecan, either alone or in combination with other treatments, for men with metastatic castrate-resistant prostate cancer that has worsened despite hormone therapy. It aims to see if this approach can help shrink or slow the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06866938RecruitingPhase 2
Second course of PSMA-targeted radiation for prostate cancer
This study tests giving the targeted radiation drug [177Lu]Lu-PSMA again to men whose prostate cancer has started growing after an earlier course of the same treatment. It aims to see if a second round can control the cancer again.
BordeauxAges 18 years+ - NCT06843668RecruitingPhase 2/Phase 3
Best ways to give colistin for tough infections in the ICU
This study tests different ways of giving the antibiotic colistin to patients in the ICU with infections that are hard to treat. The goal is to find the best dosing schedule to help you fight the infection more effectively.
BuraidahAges 18 years+ - NCT06853132Recruiting
Baduanjin with resistance training for back pain or osteoporosis
This study tests a gentle exercise program called Baduanjin combined with resistance training for people with back problems or osteoporosis who are about to have surgery. It aims to see if this type of exercise helps before and after the procedure.
Changsha, HunanAges 45 years+ - NCT06842498RecruitingPhase 2
FG-3246 for advanced prostate cancer
This trial tests a new drug called FG-3246, which targets a protein (CD46) on prostate cancer cells. It's for men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy, and who have had limited prior treatments.
Goodyear, ArizonaAges 18 years+ - NCT06835218Recruiting
Prostate cancer real-world evidence registry
This study collects information from men with prostate cancer to better understand how different treatments work in real life. It follows patients when they start a new treatment and can help improve future care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06824350Recruiting
Chlorine in water to prevent newborn infections
This trial tests whether adding a small amount of chlorine to the drinking water at public health facilities can reduce infections (including those resistant to antibiotics) in newborns. You and your baby may be eligible if you deliver at a participating facility that does not already chlorinate its water.
Berkeley, CaliforniaAges Any age - NCT06248333Recruiting
Deep brain stimulation for focal motor epilepsy
This trial tests whether deep brain stimulation of a small area in the brain can help reduce seizures that start in the motor part of the brain and do not respond to medication. It may be an option for people who cannot have surgery or whose surgery did not help enough.
Beijing, Beijing MunicipalityAges 14–65 - NCT06801236RecruitingPhase 1
A new drug for advanced prostate cancer that has stopped responding to treatment
This early-phase trial tests a new study drug called ACE-232 for men with advanced prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It aims to see if the drug is safe and may help slow the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT04250493Recruiting
Testing insulin resistance in multiple system atrophy
This study looks at how the body handles blood sugar (insulin resistance) in people with multiple system atrophy (MSA). Results may help doctors understand the disease better and explore new ways to monitor or treat it.
BordeauxAges 30 years+ - NCT06784336RecruitingPhase 2
Testing starch and a drug after stem cell transplant
This trial tests if adding a special starch and a drug called deferasirox can improve recovery for people who have a stem cell transplant for blood disorders. The starch may help with gut health and the drug reduces iron, which might help prevent complications.
Ann Arbor, MichiganAges 18 years+ - NCT05661383Recruiting
Smell and brain stimulation for hard-to-treat depression
This trial studies whether stimulating the brain and senses related to smell can reduce symptoms in people with depression that has not responded to usual treatment. It may help by testing new non-drug approaches for improving mood and motivation.
BronAges 18 years+ - NCT06205147Recruiting
Elastic band exercise for strength and mood in older hospital patients
This study tests whether using elastic bands for resistance exercises can help older adults in the hospital improve their muscle strength and reduce symptoms of depression. If you are 65 or older, staying in the hospital for more than a week, and able to follow simple instructions, this might be a good fit.
Taipei, TaiwanAges 65 years+ - NCT06749444Recruiting
Cognitive behavioral therapy for sleep issues in schizophrenia
This trial tests if a talking therapy focused on sleep and daily rhythms (CBT-I) can help people with schizophrenia who have not responded well to other treatments and have trouble sleeping. It aims to improve sleep quality without medication.
Glostrup, DenmarkAges 18–64 - NCT06743269Recruiting
Breathing Training for Stress and Sleep in Midlife Women
This study tests a simple breathing exercise (inspiratory muscle strength training) to see if it can help reduce stress and improve sleep for midlife women who have hot flashes. If you're between 45-60, have hot flashes, and don't smoke, you may be able to join.
Rochester, MinnesotaAges 45–60 - NCT06738303RecruitingPhase 2
Cabazitaxel with or without carboplatin vs lutetium PSMA for prostate cancer
This trial compares two treatment approaches for advanced prostate cancer that has stopped responding to hormone therapy. One group gets chemotherapy (cabazitaxel with or without carboplatin) and the other gets a targeted radiation therapy (177Lu-PSMA-617). The goal is to see which works better.
Cleveland, OhioAges 19 years+ - NCT05922124RecruitingPhase 4
Testing two antibiotics against resistant lung and bloodstream infections
This trial studies whether cefiderocol plus ampicillin-sulbactam works better than colistin (sometimes with meropenem) for serious infections caused by carbapenem-resistant Acinetobacter baumannii (a hard-to-treat germ). It may help by finding a more effective antibiotic plan for people with these severe hospital-acquired infections.
HaifaAges 16 years+ - NCT03671967RecruitingPhase 4
Compare two antibiotics for hard-to-treat E. coli and Klebsiella bloodstream infections
This trial tests whether piperacillin-tazobactam works as well as meropenem to treat bloodstream infections caused by certain E. coli or Klebsiella germs that resist common cephalosporin antibiotics. It may help you avoid a “bigger” antibiotic if the study drug is equally effective.
Calgary, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,198 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.