Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07546500RecruitingPhase 3
Azenosertib versus chemotherapy for advanced ovarian cancer
This trial tests a new drug called azenosertib against standard chemotherapy for ovarian, fallopian tube, or peritoneal cancer that has come back after platinum-based treatment. The drug targets a specific protein (cyclin E1) found in some tumors and may help stop cancer cells from dividing.
Phoenix, ArizonaAges 18 years+ - NCT06787612RecruitingPhase 2
New combination for platinum-resistant ovarian cancer
This study tests a new combination treatment (ubamatamab plus another drug) for people with ovarian cancer that no longer responds to platinum chemotherapy. It could be an option if your cancer has kept growing despite prior treatment.
Birmingham, AlabamaAges 18 years+ - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07347600Recruiting
Studying inavolisib for a type of advanced breast cancer
This study tests a targeted therapy called inavolisib for people whose breast cancer has spread (advanced or metastatic), is hormone receptor-positive and HER2-negative, has a PIK3CA mutation, and has stopped responding to hormone therapy. It aims to see if inavolisib is safe and works well for them.
Xiamen, FujianAges 18 years+ - NCT07158489RecruitingPhase 2
New drug combo for advanced lung cancer after immunotherapy
This trial combines gemcitabine with ivonescimab to try to overcome resistance to immunotherapy in advanced non-small cell lung cancer. It's for people whose cancer has worsened after prior immunotherapy.
BadenAges 18 years+ - NCT07755436RecruitingPhase 1
Study of ARR-002 for advanced ovarian or endometrial cancer
This study tests an experimental drug called ARR-002 in people with advanced or metastatic ovarian, primary peritoneal, or fallopian tube cancer that has stopped responding to standard treatments. The goal is to see if it is safe and whether it shrinks tumors.
Irving, TexasAges 18 years+ - NCT07412028Recruiting
Gene study in women with severe insulin resistance and PCOS
This study is looking for women with a type of severe insulin resistance linked to genetics, especially those who have PCOS or a condition called lipodystrophy. The goal is to better understand the genes involved so doctors can offer more targeted treatments.
ParisAges 18–45 - NCT06856720Enrolling by invitation
Muscle stimulation, exercise, and blood sugar control in older adults with type 2 diabetes
This study tests if combining electrical muscle stimulation with exercise can help older adults with type 2 diabetes living in nursing homes better manage their blood sugar. Participants will receive supervised sessions over several weeks.
Viseu, Viseu DistrictAges 60 years+ - NCT07543055RecruitingPhase 1
CAR T-Cell Therapy for Advanced Prostate Cancer
This trial tests BPX-601, a new type of cell therapy that uses your own immune cells to fight prostate cancer that has spread and stopped responding to hormone treatments. The study aims to see if this approach can help men whose cancer has returned despite multiple prior treatments.
Hackensack, New JerseyAges 18 years+ - NCT06785064Recruiting
Helping with long-term weight loss maintenance support
This study tests an extended care program designed to help people keep weight off after losing it. You would join with a buddy (friend or family member) and attend online sessions via Zoom, along with a few in-person check-ins at the university.
Birmingham, AlabamaAges 18 years+ - NCT06538766Recruiting
How focus instructions affect strength training and walking in older adults
This study tests whether different types of mental focus during strength training can improve walking ability in older adults. It may help find better ways to stay steady and prevent falls.
Monte de Caparica, AlmadaAges 18 years+ - NCT07751536Recruiting
Proton radiation and intrathecal chemo for lung cancer that has spread to the brain lining
This trial tests a combination of proton radiation to the brain and spine plus chemotherapy given directly into the fluid around the brain and spinal cord. It is for people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the lining of the brain and has continued to grow despite taking a third-generation TKI medicine like osimertinib.
Hefei, AnhuiAges 18–75 - NCT07549256RecruitingPhase 2
Cannabidiol for Pain Relief in Advanced Prostate Cancer
This trial tests whether cannabidiol (CBD), a non-intoxicating cannabis compound, can help relieve pain in patients with advanced prostate cancer that has stopped responding to standard treatments. You would take CBD daily alongside your current morphine pain medication.
GistrupAges Any age - NCT06636890Enrolling by invitation
Testing a new method for detecting certain bacteria in lung infections
This study checks if a special test (Xpert Carba-R) can find a type of drug-resistant bacteria, called CRE, in fluid from the lungs and in rectal swabs. It might help doctors treat lower respiratory tract infections more effectively.
Nanjing, JiangsuAges 18–90 - NCT06606704Recruiting
Strength bands and creatine for healthy older adults
This study tests whether a simple home exercise program using resistance bands, combined with a creatine supplement, can help improve muscle strength and health in older adults who are not already doing regular strength training.
Regina, SaskatchewanAges 50 years+ - NCT06262009Recruiting
Tracking antibiotic resistance in people and their dogs
This study looks at how antibiotic-resistant bacteria spread between people and their dogs in the same home. It aims to understand how these germs persist and change over time in humans, animals, and the environment.
Maisons-AlfortAges Any age - NCT06232213Recruiting
Personalized treatment for relapsed or drug-resistant gynecological cancers
This trial tests a personalized approach to treating advanced ovarian or endometrial cancers that have come back or stopped responding to standard treatments. It uses a special model to guide which therapy might work best for you.
Beijing, Beijing MunicipalityAges 18–80 - NCT04715022RecruitingTeam says not enrollingPhase 1/Phase 2
Vitamin C study for insulin resistance in obesity
This early-stage study tests whether vitamin C (and possibly how your body uses it) affects blood vessel function in people with obesity and insulin resistance. You may be asked to stop certain supplements before starting so researchers can measure the effect more clearly.
Kansas City, KansasAges 35–65 - NCT07749508Recruiting
Study on gram-negative bacterial infections
This study looks at infections caused by gram-negative bacteria (a type of bacteria that can cause serious illness). It aims to learn more about these infections and how to treat them, which might help improve care for patients with such infections.
Madrid, MadridAges Any age - NCT07223151Recruiting
A taste test to help teens drink fewer sugary sodas
This study tests whether a special way of tasting sweet drinks can help teens who love sugary beverages cut back on them. It might help you reduce sugar and improve your health.
Bloomington, IndianaAges 12–18 - NCT07213804RecruitingPhase 3
Study of sofetabart mipitecan for ovarian cancer
This trial tests a new drug called sofetabart mipitecan for people with ovarian cancer that has come back after treatment. It is for those whose cancer is either resistant to platinum chemo (Part A) or sensitive to it (Parts B and C). The study will see if the drug can help shrink or slow the cancer.
Birmingham, AlabamaAges 18 years+ - NCT07623135RecruitingPhase 3
Lumateperone for Hard-to-Treat Depression in Older Adults
This study tests lumateperone, a new medication added to your current antidepressant, to help treat depression that hasn't improved with other treatments. It's designed for people age 60 and older who have tried at least two antidepressants without success.
Tucson, ArizonaAges 60 years+ - NCT07474974Recruiting
Can Eye Cells Predict TMS Success for Depression?
This study tests whether a specific type of eye cell can predict how well transcranial magnetic stimulation (TMS) works for treating depression. TMS is a non-invasive brain stimulation method that may help people with depression that hasn't responded to other treatments.
Porto, Porto DistrictAges 18–65 - NCT07214779RecruitingPhase 3
New drug vs chemo for platinum-resistant ovarian cancer
This study tests a new drug (INCB123667) given as a pill, compared to standard chemotherapy, for people whose ovarian cancer has stopped responding to platinum-based treatments and whose tumor has high levels of a protein called Cyclin E1. The goal is to see if the new drug works better than standard chemo for this specific type of cancer.
Anchorage, AlaskaAges 18 years+
Hear when a new Resistance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,200 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.