Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06966752Recruiting
Comparing two breathing supports for preterm babies with breathing problems
This study compares two types of breathing support (CPAP and NIPPV) for preterm babies with breathing problems. It aims to find which method works better for helping babies breathe easier.
Vilnius, Vilnius CountyAges birth–10 months - NCT07086755RecruitingPhase 2/Phase 3
Vadadustat treatment for lung injury from infection
This trial tests a pill called vadadustat for people with a serious lung condition called ARDS, which makes it hard to breathe. The drug may reduce inflammation and improve oxygen levels, helping patients recover without needing a breathing tube.
Houston, TexasAges 18 years+ - NCT07090460Recruiting
Measuring lung overstretch in prone-position ARDS patients
This study uses a special imaging belt (EIT) to check if the lungs are being overstretched when patients with severe breathing problems are placed on their stomach (prone position). It may help doctors adjust breathing machines more safely.
Bayonne, Centre Hospitalier de La Côte BasqueAges 18 years+ - NCT07083973Recruiting
Monitoring lung function with 3D imaging in ARDS
This study is testing a new way to monitor lung function using a 3D electrical imaging device (EIT) while patients with ARDS lie on their stomach to improve breathing. The goal is to see if this imaging helps doctors better understand how the lungs are working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT06874478Recruiting
Breathing help for babies born by planned C-section
This study looks at whether giving steroids before a planned C-section at full term can help babies breathe better after birth. It may be an option for pregnant women who are scheduled for a C-section and meet certain health criteria.
AsyutAges 20–39 - NCT06720818Recruiting
Infection-fighting cells in severe lung injury
This study looks at a type of immune cell (MAIT cell) in patients with severe lung problems caused by infections, pancreatitis, head injury, burns, or major surgery. It aims to understand how these cells change during illness, which may lead to better treatments.
ToursAges 18 years+ - NCT06188195Recruiting
Preventing newborn breathing problems with steroids
This study tests a plan to prevent a severe newborn breathing problem called NARDS. If your baby's risk is very high, you may be offered a steroid treatment that could help their lungs work better at birth.
ChongqingAges Any age - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT04777760Recruiting
Surfactant treatment for newborn breathing distress
This trial looks at giving a “surfactant” medicine (a substance that helps keep baby lungs open) to newborns who have serious breathing problems soon after birth. It may help babies with neonatal respiratory distress or acute breathing distress, especially if they’re treated in the early time window.
Chongqing, Chongqing MunicipalityAges 1 minute–1 day - NCT06849570Recruiting
Tailoring breathing support and muscle relaxants during prone positioning for severe lung injury
This trial tests two ways to adjust ventilator settings for patients with severe lung injury whose oxygen levels are very low. It aims to find out the best level of breathing support and whether giving muscle relaxants during prone positioning helps improve oxygen levels.
Aix-en-ProvenceAges 18 years+ - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT06807983Recruiting
Lung and heart ultrasound for breathing trouble in older adults
This trial tests whether using lung and heart ultrasound (LuCUS) can help emergency doctors better diagnose and treat shortness of breath in patients over 65. It aims to improve care for older adults with severe breathing problems.
ToulouseAges 65 years+ - NCT06701682RecruitingPhase 2
Study of vilobelimab for moderate to severe ARDS
This trial tests a drug called vilobelimab for people with moderate or severe ARDS (a serious lung condition). It aims to find if this treatment can help improve breathing and outcomes.
Birmingham, AlabamaAges 18 years+ - NCT06701656RecruitingPhase 2
Testing bevacizumab for breathing problems from ARDS
This trial tests if bevacizumab can help people with ARDS (a serious lung condition) breathe better. It is for patients with mild, moderate, or severe ARDS who are already in the hospital.
Birmingham, AlabamaAges 18 years+ - NCT06701669RecruitingPhase 2
Study of Paridiprubart for moderate to severe ARDS
This trial tests a new medicine called paridiprubart to see if it can help people with moderate or severe acute respiratory distress syndrome (ARDS), a serious lung condition. It may be an option if you have low oxygen levels and no known allergy to the drug.
Birmingham, AlabamaAges 18 years+ - NCT06703073RecruitingPhase 2
Testing new treatments for acute respiratory distress syndrome (ARDS)
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
Birmingham, AlabamaAges 18 years+ - NCT06684379RecruitingPhase 1/Phase 2
Two Doses of PRS CK STORM for Severe Viral Pneumonia
This study tests a new drug called PRS CK STORM to see if it can safely calm the body's overactive immune response (cytokine storm) in people with severe pneumonia from COVID-19, flu, or RSV who need oxygen. It aims to reduce inflammation and improve recovery.
Alcalá de Henares, MadridAges 18 years+ - NCT06598709Enrolling by invitation
International study on breathing tube removal in ARDS
This study looks at how doctors safely remove breathing tubes from patients with lung injury (ARDS). It aims to find ways to improve decisions about when to take the tube out.
HiroshimaAges 16 years+ - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT06536543Recruiting
Lung imaging to check over-inflation in ARDS patients lying on their stomach
This trial uses a special lung imaging belt (EIT) to see if the lungs are over-inflated in patients with severe breathing problems (ARDS) when they lie on their stomach. It aims to help doctors adjust ventilator settings for better lung protection.
BayonneAges 18 years+ - NCT06513949RecruitingPhase 2
Testing IC14 for ARDS on a ventilator
This trial tests a new treatment called IC14 for people in the hospital on a breathing machine for ARDS (a severe lung injury). The study aims to see if IC14, which blocks a protein involved in inflammation, can help the lungs heal faster.
Seattle, WashingtonAges 18 years+ - NCT06446453Recruiting
Lung Ultrasound-Guided Surfactant For Preterm Infants
This study tests whether giving surfactant medication guided by a lung ultrasound, instead of by X-ray, helps preterm babies with breathing problems get better without needing a breathing tube. Babies in the study receive surfactant through a thin tube while still on non-invasive breathing support.
Hartford, ConnecticutAges birth–2 hours
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Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 200 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.