Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07426016Recruiting
Comparing two ways to give surfactant to premature babies
This study compares two methods—video laryngoscopy and direct laryngoscopy—to give surfactant (a medicine that helps babies' lungs work better) to very premature infants. It aims to find which method is safer and easier for babies born at 28 weeks or earlier who need surfactant within the first 36 hours after birth.
Dallas, TexasAges birth–3 days - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT07395076Recruiting
Study of immune causes of acute respiratory distress
This trial looks at how the immune system might cause severe breathing problems (ARDS). It may help doctors understand what happens in the lungs during this condition and find better ways to treat it.
ParisAges 18 years+ - NCT06758492Recruiting
Video vs direct laryngoscopy for surfactant in newborns
This study compares two ways of placing a thin tube into a newborn's windpipe to give surfactant—a medicine that helps their lungs work better. It will help doctors understand which method is safer and easier for babies needing this treatment.
RijekaAges birth–4 weeks - NCT07380373Enrolling by invitation
Testing markers in body fluids for lung injury in children
This study looks at two substances in saliva and lung fluid—called IL-6 and TNF-α—in children with severe lung failure (ARDS) who are on a breathing machine. Measuring these markers may help doctors better understand the condition and guide treatment.
CairoAges 1–10 - NCT07350018RecruitingPhase 4
Comparing Two Surfactants for Premature Babies With Breathing Problems
This trial compares two types of surfactant (Calfactant and Poractant Alfa) given through a less invasive method to very premature babies with breathing problems. It aims to see if one works better at helping them breathe without needing a breathing tube.
BursaAges birth–6 hours - NCT07344714Recruiting
Predicting breathing help needs for newborns in NICUs
This study looks at newborns in a lower-level NICU to see which ones will need extra breathing support. The goal is to better predict which babies can be kept at their current hospital instead of being moved.
Rochester, MinnesotaAges 7 months–9 months - NCT06774534Recruiting
SerpinB3 protein in acute respiratory distress
This study looks at a protein called SerpinB3 and its role in severe lung inflammation (ARDS). It may help doctors understand how ARDS develops and find new ways to treat it.
Padova, PDAges 18 years+ - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT07317050RecruitingPhase 3
Aprotinin for acute respiratory distress syndrome
This trial tests a drug called aprotinin for people with moderate to severe ARDS who are on a breathing machine. The goal is to see if it helps treat the lung injury.
Ciudad Real, Ciudad RealAges 18 years+ - NCT07289711Recruiting
Study of ARDS subtypes for targeted treatment
This study looks at different types of inflammation in patients with Acute Respiratory Distress Syndrome (ARDS), a serious lung condition. It aims to find which treatments work best for each subtype.
Nanjing, JiangsuAges 18 years+ - NCT05731024Recruiting
Closed-loop breathing control vs standard care for kids in ICU
This study compares a computerized “closed-loop” system that helps match breathing support to a child’s needs versus usual (standard) breathing control. It’s for critically ill children on a breathing machine, aiming to improve synchronization between the child and the ventilator.
AydinAges 1 month–18 years - NCT06051292Recruiting
Testing balloon size for lung pressure measurement in children
This study tests how much air to put in a small balloon in the esophagus (feeding tube-like device) to measure lung pressure more accurately. It is for children on a breathing machine whose settings are stable for the next 2 hours.
AydinAges 1 month–18 years - NCT06357780Recruiting
Comparing two breath-timing methods for breathing masks in adults
This study compares two ways of timing a breathing mask's support to match your own breaths. If you're in the ICU or ER and need help breathing for at least 2 more hours, this trial may test which method works better.
IzmirAges 18 years+ - NCT07261787RecruitingPhase 4
Surfactant given in 1 vs. 5 minutes for very preterm babies
This trial compares giving a breathing treatment (surfactant) over 1 minute versus 5 minutes to help very premature babies born before 28 weeks. The goal is to see which timing helps the baby's breathing and heart rate stabilize better.
GrazAges birth–3 days - NCT07251790Recruiting
Better breathing support for very preterm babies
This trial tests different ways to help very preterm babies when they are first taken off a breathing machine and switched to CPAP. It aims to find the safest and most effective breathing support to help them breathe on their own.
Melbourne, VictoriaAges birth+ - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT07208591RecruitingPhase 3
Test of an experimental drug for severe viral lung infection (ARDS)
This study tests an experimental drug (STSA-1002) for people with severe breathing problems caused by a viral infection. It aims to see if the drug can help improve oxygen levels and reduce the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–85 - NCT07202299Recruiting
Weaning preterm babies off high-frequency breathing machines
This trial tests two different ways to safely take preterm babies off a special breathing machine (HFOV). It aims to find which method works better for babies with breathing problems (respiratory distress syndrome).
Al MansurahAges Any age - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06936618Recruiting
Electrical impedance guided ventilator settings for breathing failure
This trial tests whether using electrical impedance tomography (EIT), a safe and non-invasive monitoring technique, helps doctors set the ventilator better for patients with low oxygen levels. It may improve your breathing support during mechanical ventilation.
BangkokAges 18 years+ - NCT07162285Enrolling by invitation
Bubble CPAP for Preterm Babies with Breathing Problems
This trial tests a special breathing support called bubble CPAP, given right after birth in the delivery room, to help preterm babies (born before 34 weeks) who are having trouble breathing. It aims to see if starting this treatment early can improve their breathing and health.
DhakaAges 5 minutes–30 minutes - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months
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Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 200 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.