Clinical trials
Respiratory Failure clinical trials
Below are recruiting respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06808997Recruiting
Study on breathing support decisions for very early preterm babies
This study looks at how doctors decide when to remove the breathing tube (extubation) from extremely preterm babies born before 28 weeks of pregnancy. It aims to understand what affects breathing outcomes and could help improve care for these tiny infants.
AmiensAges 1 minute–5 months - NCT07203781Recruiting
Breathing machine settings and their effect on breathing effort
This study is testing how different settings on a breathing machine affect your breathing effort and drive. It may help doctors find the best ventilator settings for patients with severe low oxygen levels.
Nijmegen, GelderlandAges 18 years+ - NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT06819644RecruitingPhase 3
Adjusting oxygen therapy using a depth camera to measure lung volumes
This trial tests whether adjusting high flow oxygen therapy (which delivers warm, moist oxygen through the nose) based on a new, non-contact technology — a depth camera that measures lung volumes without touching you — can help improve breathing in people with low oxygen levels. It's for patients in respiratory distress who need oxygen but don't have chronic lung disease.
BrestAges 18 years+ - NCT07517497Recruiting
Lung Vibration Device for Seniors With Hip Fracture and Breathing Problems
This study tests a special vibration device on the chest to help older adults who have both a hip fracture and acute breathing failure recover better. The device uses gentle vibrations to help clear the lungs and improve breathing.
AstanaAges 60–85 - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT06307392Recruiting
Bougie versus tube for first-attempt breathing tube success
This trial compares two methods of placing a breathing tube during a medical emergency outside the hospital: using a flexible device called a bougie versus just the tube alone. It aims to see which method is more successful on the first try.
Nantes, Loire AtlantiqueAges 18 years+ - NCT05756387Recruiting
Improving nighttime home breathing support for people with COPD
This study tests different ways to improve chronic noninvasive nighttime breathing support at home for people with COPD. It may help make home treatment easier and more effective, using better tools and setup.
GroningenAges Any age - NCT06769360Recruiting
Pressure support breathing trial for ICU patients
This trial tests a new way to set the breathing machine's pressure support based on your muscle effort. It may help you breathe more comfortably and improve recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06322719Recruiting
Comparing two blades for intubation in the ICU
This trial tests which blade (hyperangulated or Macintosh) works better when doctors use a video laryngoscope to place a breathing tube in intensive care patients. It may help improve how intubation is done in the ICU.
Santiago de Compostela, A CoruñaAges 18–90 - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT05144633Recruiting
AI and sound checks to help adults with sudden breathing problems
This trial tests whether an artificial intelligence tool and quick lung sound exams can better help doctors manage adults who arrive at the emergency room or are newly admitted with sudden worsening breathing and new oxygen needs. It may help by improving how lung problems are recognized early.
Louisville, KentuckyAges 18–100 - NCT06401239Recruiting
Study on recovery from severe breathing problems
This study looks at how recovery goes for people who had severe breathing problems in the hospital. It involves talking with you and a partner who helps care for you, to learn how to improve support for both of you.
Baltimore, MarylandAges 18 years+ - NCT06123143Recruiting
Finding the best time to stop CPAP in very small babies
This study looks at when to safely take very small babies (born before 30 weeks) off breathing support called CPAP. It aims to find the ideal time to help their lungs grow stronger.
Escondido, CaliforniaAges Up to 7 months - NCT07532811Recruiting
How Lungs Distribute Air and Blood in Critically Ill Children
This pilot study uses a special belt around the chest to measure how air and blood are distributed in the lungs of children on breathing machines in the intensive care unit. The goal is to better understand lung function in critically ill children.
Bron, FranceAges Up to 12 years - NCT07536984Enrolling by invitation
Personalized Oxygen Levels for Breathing Machine Patients
This study tests whether adjusting oxygen levels on a breathing machine (ventilator) to match each patient's individual needs improves outcomes. Doctors will carefully monitor your oxygen levels and see how different targets affect your recovery.
Nashville, TennesseeAges 18 years+ - NCT06934876Recruiting
Comparing two CO2 detectors during breathing tube placement in critically ill adults
This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.
Chicago, IllinoisAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT06855004Recruiting
Study of severe breathing problems in people with lung scarring
This study follows patients with chronic lung scarring (fibrosing interstitial lung disease) who are in the intensive care unit for severe breathing failure. It aims to better understand their condition and care, which may help improve future treatments.
BobignyAges 18 years+ - NCT07428694Recruiting
Detecting air leaks during breathing support
This trial tests a machine learning tool to detect if air is leaking while using a breathing machine at night. It may help people who use a non-invasive ventilator at home get better care.
OsloAges 18 years+ - NCT07007715Recruiting
Finding the best oxygen flow setting after extubation
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
TaipeiAges 18 years+
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Common questions
- Are there clinical trials for respiratory failure?
- Yes. Clin2 currently lists 209 recruiting respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.