Clinical trials
Respiratory Failure clinical trials
Below are recruiting respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06769360Recruiting
Pressure support breathing trial for ICU patients
This trial tests a new way to set the breathing machine's pressure support based on your muscle effort. It may help you breathe more comfortably and improve recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07419438Recruiting
Airway device study for preterm babies needing breathing help
This study tests a supraglottic airway device (a tube that sits above the voice box) versus a face mask for helping premature babies breathe right after birth. It may help doctors choose the best way to support your baby's first breaths.
Philadelphia, PennsylvaniaAges birth–1 day - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT07359261RecruitingPhase 2
Personalized breathing support for obese patients on a ventilator
This study tests a new way to adjust breathing machine settings to match each person's lungs, aiming to improve breathing for patients with obesity. It involves placing a small balloon in the esophagus to measure lung pressure and guide ventilator settings.
Edmonton, AlbertaAges 18 years+ - NCT06855004Recruiting
Study of severe breathing problems in people with lung scarring
This study follows patients with chronic lung scarring (fibrosing interstitial lung disease) who are in the intensive care unit for severe breathing failure. It aims to better understand their condition and care, which may help improve future treatments.
BobignyAges 18 years+ - NCT07324980Recruiting
Ultrasound for breathing trouble in the ER
This study tests if a quick ultrasound can help doctors figure out why you are having trouble breathing when you come to the emergency room. It may lead to faster and more accurate care.
NovaraAges 18 years+ - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT07313956Enrolling by invitation
Breathing machine method study in the ICU
This study looks at how different settings on the breathing machine (ventilator) are used for critically ill adults in the ICU. It may help doctors improve care for people who need a breathing tube.
Chicago, IllinoisAges 18 years+ - NCT05014581RecruitingPhase 3
Testing vasopressors to prevent low blood pressure during intubation
This trial studies whether using blood-pressure support medicines (vasopressors) during breathing tube placement (intubation) can prevent dangerous drops in circulation (“cardiovascular collapse”). It may help patients stay stable during and after intubation, especially in critical illness.
NantesAges 18–90 - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07223762Enrolling by invitation
Comparing two types of laryngoscope blades for intubation
This trial compares two types of laryngoscope blades (the tool used to guide a breathing tube) to see which works better for routine intubations. If you are an adult scheduled for a planned breathing tube placement, you may be able to join.
Birmingham, AlabamaAges 18 years+ - NCT06709456Recruiting
Draining fluid from lungs in the ICU
This trial tests whether draining fluid that builds up around the lungs helps patients with breathing problems in the intensive care unit. You may be eligible if you are in the ICU, have at least 2 cm of fluid on an ultrasound or CT scan, and need extra oxygen or a breathing machine.
AalborgAges 18 years+ - NCT04666246Recruiting
Studying breathing effort in people with COVID-19 breathing failure
This study looks at how hard people with COVID-19 are working to breathe when they have serious breathing trouble but are not yet fully on a breathing machine. The results may help doctors better understand breathing support needs and improve care.
ModenaAges 18–80 - NCT07186933Recruiting
Ventilator settings to protect lungs during high-risk surgery
This study compares two ways of setting the ventilator during surgery to reduce lung complications. Researchers will test whether using a lower 'driving pressure' (a setting on the breathing machine) helps protect the lungs better than usual care. It is for adults having high-risk surgeries under general anesthesia with a breathing tube.
PátraiAges 18 years+ - NCT07156669Recruiting
Safety and Performance of Novalung ECMO Kit and Xenios 2.0
This study is testing how well a special ECMO device (Novalung ultimate kit with Xenios 2.0) works for adults in the hospital and during ground transport. If you already need ECMO with this specific device, you may be able to join.
Erfurt, BavariaAges 18 years+ - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT05011877Recruiting
Study for sleep testing after sudden breathing trouble
This trial studies people who unexpectedly end up in the hospital or emergency room because of a sudden worsening in breathing that leads to too much carbon dioxide. It may help doctors understand whether sleep-related breathing issues contribute and how to better prevent repeat episodes.
Toronto, OntarioAges 18 years+ - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT07047092RecruitingPhase 3
CPAP vs. NIV for sleep apnea in COPD after breathing failure
This trial compares two breathing devices (CPAP and NIV) for people with both COPD and sleep apnea who recently needed breathing help in the hospital. The goal is to see which device works better at preventing future breathing emergencies.
ParisAges 18–84 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07007715Recruiting
Finding the best oxygen flow setting after extubation
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
TaipeiAges 18 years+ - NCT07001696Recruiting
Predicting breathing support needs with chest X-ray and blood gas
This trial looks at whether combining a chest X-ray and a blood gas test can help doctors decide if a critically ill patient needs a breathing machine (mechanical ventilation). It aims to find a better way to make this important decision.
Zagazig, Al SharqiaAges 18 years+ - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+
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Common questions
- Are there clinical trials for respiratory failure?
- Yes. Clin2 currently lists 198 recruiting respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.