Clinical trials
Respiratory Failure clinical trials
Below are recruiting respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06996834Recruiting
Comparing breathing support methods for pneumonia-related breathing failure
This trial tests two noninvasive breathing support methods (NIV and HVNI) for people with pneumonia who are having trouble breathing. The goal is to see which method works better to help you avoid needing a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT06996665Recruiting
High-flow nasal cannula based on diaphragm ultrasound
This study uses ultrasound to match high-flow oxygen settings to your diaphragm's movement. It looks at how breathing muscles respond at different flow rates to give you the best support.
Hangzhou, ZhejiangAges 18 years+ - NCT06039501Recruiting
The Family Perspectives Project Pilot Trial
This study looks at how to improve communication between families and the care team when a loved one is on a breathing machine in the intensive care unit. It may help families feel more supported and involved in care decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT06939361Enrolling by invitation
Tube size study during emergency breathing tube placement
This trial compares different sizes of breathing tubes used in emergencies to see which works best. It helps doctors choose the right tube for patients who need help breathing.
Birmingham, AlabamaAges 18 years+ - NCT06934876Recruiting
Comparing two CO2 detectors during breathing tube placement in critically ill adults
This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.
Chicago, IllinoisAges 18 years+ - NCT06921655Recruiting
Using pressure and muscle measurement to avoid too much breathing help in the ICU
This study tests a new way to adjust the breathing machine settings for patients who are awake and breathing on their own but still need support. The goal is to avoid giving too much help, which can make the breathing muscles weak.
Trento, TrentoAges 18 years+ - NCT01571986Recruiting
Improving non-invasive breathing support
This study is looking at ways to improve non-invasive ventilation, which is breathing support given without a breathing tube. You may be invited if you’re already receiving this kind of support and you agree to take part.
MilanAges 18–99 - NCT06848218Recruiting
Music therapy during non-invasive breathing support for children
This study tests if music therapy can help children who are receiving breathing support (non-invasive ventilation) in the pediatric intensive care unit. It aims to reduce stress and discomfort during treatment.
MontpellierAges Up to 17 years - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06244160Recruiting
High-flow oxygen therapy for spinal cord injury
This trial tests if high-flow oxygen therapy can help people with spinal cord injuries between the neck and upper back. It is designed for those admitted to a spinal injury ward within 24 to 48 hours of injury.
CardiffAges 18 years+ - NCT06615492Recruiting
Lung transplant study: comparing two ECMO methods
This study compares two ways of using a heart-lung machine (ECMO) during lung transplant surgery. The goal is to see if using ECMO only when needed works as well as using it for everyone. This could help reduce risks and improve recovery.
Edmonton, AlbertaAges 18 years+ - NCT06591533Recruiting
Music therapy for children during breathing tube removal
This study uses music therapy to help children stay calm and have stable vital signs while their breathing tube is removed. It may help reduce stress during this important step.
Bogotá, Bogota D.C.Ages 1 month–17 years - NCT06102499Recruiting
Comparing oxygen readings from different pulse oximeters in the ICU
This study tests how well different pulse oximeters measure oxygen levels compared to a direct blood test in patients in the intensive care unit. It aims to find which devices are most accurate for monitoring oxygen.
Montreal, QuebecAges birth–100 years - NCT05590130Recruiting
Test two oxygen targets using different oxygen monitors
This study compares how much oxygen is needed and how well oxygen levels stay in a safe range after heart surgery in the ICU. It also tests whether using different oxygen monitors affects oxygen flow and oxygenation.
Québec, QuebecAges 18 years+ - NCT06526598Recruiting
Breathing support tailored to your effort in the ICU
This trial tests a new way of adjusting breathing machine support based on how hard you are breathing. It may help people with low oxygen levels who need a ventilator.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06441760Recruiting
Telemedicine support for paramedics in children's emergencies
This study tests whether paramedics and emergency doctors can use a special video or phone link to improve care for children in emergencies. It compares the usual way doctors give advice to paramedics with a new telemedicine method.
Los Angeles, CaliforniaAges 21 years+ - NCT06454006Recruiting
Light therapy for patients on breathing machines
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
Porto Alegre, Rio Grande do SulAges 21 years+ - NCT06443970Recruiting
Comparing suctioning methods for babies on breathing tubes
This study compares two ways of suctioning the breathing tube in newborns who are on a ventilator. It aims to see which method is safer and more effective for your baby.
New York, New YorkAges Up to 4 weeks - NCT06438302Recruiting
Nasal ventilation for patients on a breathing machine
This trial tests whether using a nasal ventilation mask affects how well the brain and lungs work in people who are already on a breathing machine. It is for patients with very low oxygen levels who have been intubated for less than 4 days.
ParisAges 18 years+ - NCT06401239Recruiting
Study on recovery from severe breathing problems
This study looks at how recovery goes for people who had severe breathing problems in the hospital. It involves talking with you and a partner who helps care for you, to learn how to improve support for both of you.
Baltimore, MarylandAges 18 years+ - NCT06322719Recruiting
Comparing two blades for intubation in the ICU
This trial tests which blade (hyperangulated or Macintosh) works better when doctors use a video laryngoscope to place a breathing tube in intensive care patients. It may help improve how intubation is done in the ICU.
Santiago de Compostela, A CoruñaAges 18–90 - NCT06307392Recruiting
Bougie versus tube for first-attempt breathing tube success
This trial compares two methods of placing a breathing tube during a medical emergency outside the hospital: using a flexible device called a bougie versus just the tube alone. It aims to see which method is more successful on the first try.
Nantes, Loire AtlantiqueAges 18 years+
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Common questions
- Are there clinical trials for respiratory failure?
- Yes. Clin2 currently lists 198 recruiting respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.