Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05044403Recruiting
Hemoperfusion for severe sepsis causing multiple organ failure
This study tests whether a blood-filter treatment called hemoperfusion can help critically ill people with sepsis that is not responding to standard shock treatment and is affecting multiple organs. It aims to improve recovery when infections are controlled and inflammation markers are very high.
Castellon, CastellónAges 18–80 - NCT06910891Recruiting
Studying microcirculation to treat sepsis early
This trial tests a special way to monitor tiny blood vessels (microcirculation) in patients with sepsis. The goal is to see if early treatment based on these readings can help improve recovery.
BrivéAges 18 years+ - NCT06893939RecruitingPhase 2/Phase 3
Feeding approach for very premature babies
This study compares two ways of starting tiny feedings in very premature babies. The goal is to see if a shorter or longer period of very small feedings leads to better growth and fewer feeding problems. If you are okay with your baby receiving donor breast milk when needed, this trial may be a good fit.
Birmingham, AlabamaAges birth–2 years - NCT06887140Recruiting
Heart-lung function test in sepsis patients
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working with your lungs during sepsis. The goal is to see if this measurement can help doctors predict how patients will recover.
Ho Chi Minh CityAges 18 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT06853301Recruiting
A faster test to find bloodstream infections
This study tests a new machine learning method to quickly identify bacteria in the blood using special sample bottles. If you are getting blood cultures done already, this may help get results faster.
GrenobleAges 18 years+ - NCT06824350Recruiting
Chlorine in water to prevent newborn infections
This trial tests whether adding a small amount of chlorine to the drinking water at public health facilities can reduce infections (including those resistant to antibiotics) in newborns. You and your baby may be eligible if you deliver at a participating facility that does not already chlorinate its water.
Berkeley, CaliforniaAges Any age - NCT06808100Enrolling by invitation
Can a blood test predict organ failure in septic shock?
This trial is studying a blood marker called GDF-15 to see if it can predict which patients with septic shock might develop multiple organ failure. If you have septic shock and do not have certain other serious health conditions, you may be able to join.
AnkaraAges 18 years+ - NCT06771830Recruiting
Study of a tool that helps spot sick kids early
This study looks at a tool called pediatric eCART that helps nurses and doctors know which children in the hospital might be getting sicker. Researchers want to see if it works well to improve care.
Madison, WisconsinAges Up to 17 years - NCT06772675Recruiting
Reducing vancomycin in NICU babies
This study asks NICUs to reduce the use of the antibiotic vancomycin. It's for hospital units that are part of certain networks and agree to follow the study plan.
Modesto, CaliforniaAges 18 years+ - NCT06709573RecruitingPhase 4
Early vs. late vasopressin for septic shock
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
Cleveland, OhioAges 18 years+ - NCT05815628Recruiting
Testing next-generation sequencing in neutropenic sepsis
This trial studies whether advanced genetic testing (next-generation sequencing) can help doctors better understand and manage neutropenic sepsis—a serious infection risk when white blood cell counts are too low. You may be considered if you develop fever or sepsis quickly (within 24 hours) while your counts are low.
CologneAges 18 years+ - NCT06694181Recruiting
Safe and explainable AI for heart, sepsis, and breast cancer patients
This trial uses artificial intelligence (AI) to create prediction models for three groups: cardiology patients, sepsis patients, and breast cancer patients. It aims to make these models safe and easy to understand for doctors.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90 - NCT06601998Recruiting
Heart health after severe pneumonia
This study looks at how heart health changes in people who have recovered from severe pneumonia, including COVID-19. It compares survivors to healthy people and those with heart risk factors.
AlexandroupoliAges 18 years+ - NCT06608849Recruiting
Long-term health effects after COVID-19
This study looks at how COVID-19 may affect the lungs, heart, and kidneys in the months or years after the infection. It compares three groups: people who never had COVID, people who had COVID but recovered without organ problems, and people who had organ problems during COVID. The goal is to understand what long-term complications might arise.
AthensAges 18 years+ - NCT06521502Recruiting
Studying inflammation in the heart and lungs in the ICU
This study collects blood samples from people in the ICU with sudden heart or lung problems caused by inflammation. The goal is to learn more about these conditions and improve future treatments.
Fresno, CaliforniaAges 18 years+ - NCT06517810Recruiting
QUELIMMUNE pediatric surveillance registry
This registry tracks children treated with QUELIMMUNE therapy to see how well it works over time. It helps doctors learn more about the treatment's safety and effects in kids.
Birmingham, AlabamaAges Up to 22 years - NCT05623722Recruiting
Nerve block to help organ function in severe gut sepsis
This trial studies whether an erector spinae plane nerve block (a pain-control injection near the spine) can improve organ health in adults with sepsis caused by acute gut injury. It’s meant for people sick enough to need ICU care for several days.
Guangzhou, GuangdongAges 18 years+ - NCT06499701Recruiting
Study of Fluid Resuscitation in Early Sepsis
This trial studies how different fluids given to treat early sepsis affect the body's fluid balance. Participating may help researchers find better ways to treat sepsis-related low blood pressure and organ failure.
Bucharest, BucharestAges 18 years+ - NCT06464510RecruitingPhase 3
Treating sepsis with norepinephrine plus early vasopressin
This trial tests whether giving a second medicine called vasopressin early (along with norepinephrine) helps people with sepsis and low blood pressure better than waiting to use vasopressin only if norepinephrine doesn't work. It may improve blood pressure control and reduce the need for strong medicines.
Caxias do Sul, Rio Grande do SulAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.