Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04513288Recruiting
Immunonutrition with L-citrulline for ICU sepsis patients
This trial tests whether adding L-citrulline to tube feeding (enteral nutrition) can improve outcomes for people in the ICU with sepsis or septic shock. It may help support the body’s immune response while you’re critically ill.
Rennes, Brittany RegionAges 18 years+ - NCT05349370Recruiting
Track how lactate levels change in septic shock
This study measures how quickly a blood marker called lactate rises or falls in people with septic shock. It may help doctors understand which patterns are linked to recovery and guide better treatment decisions.
Stockholm, Stockholm CountyAges 18 years+ - NCT05928767Recruiting
Using frailty scores to predict death in ICU sepsis
This trial checks whether a “frailty” rating (how physically/mentally vulnerable someone is) can predict the risk of death in ICU patients with sepsis shock. It may help doctors identify higher-risk patients earlier and tailor care.
BéthuneAges 18–65 - NCT06140147Recruiting
Reducing fluids in septic shock care
This study tests if giving fewer fluids (other than the fluids to keep blood pressure up) can help people recover from septic shock. It compares a reduced fluid strategy to the usual care in the ICU.
HelsinkiAges 18 years+ - NCT06500156Recruiting
Metabolic patterns in septic shock patients
This study looks at how the body uses energy (metabolism) in people with septic shock. It collects information from standard monitoring during a fluid challenge (a small IV fluid test) to find patterns that might help doctors better understand and treat septic shock.
Sabadell, BarcelonaAges 18 years+ - NCT06568744Recruiting
Fluid safety limits study for septic shock patients
This trial tests whether using specific safety signals can prevent harm from too much fluid given during septic shock. It may help guide doctors to stop fluids at the right time.
QuillotaAges 18–100 - NCT06572995Recruiting
Fluid monitoring during septic shock recovery
This study is for adults in the intensive care unit with septic shock (a severe infection that drops blood pressure). It looks at how well your body holds fluid and whether treatment can be safely reduced.
BrestAges 18–99 - NCT06709573RecruitingPhase 4
Early vs. late vasopressin for septic shock
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
Cleveland, OhioAges 18 years+ - NCT07255378Recruiting
Vasopressin for septic shock in the ICU
This study observes how the medication vasopressin works when added to standard treatment for septic shock in the ICU. It helps doctors understand if vasopressin improves outcomes for patients with severe infection and low blood pressure.
Terrassa, BARCELONAAges 18 years+ - NCT07550400Recruiting
Ultrasound Imaging to Guide Septic Shock Treatment
This study tests whether using ultrasound (heart imaging and blood-vessel scanning) helps doctors treat septic shock—a life-threatening blood infection—more effectively. The trial measures whether these imaging tools help guide fluid and medication decisions during resuscitation.
CairoAges 18–50 - NCT06808100Enrolling by invitation
Can a blood test predict organ failure in septic shock?
This trial is studying a blood marker called GDF-15 to see if it can predict which patients with septic shock might develop multiple organ failure. If you have septic shock and do not have certain other serious health conditions, you may be able to join.
AnkaraAges 18 years+ - NCT07388628Recruiting
Observing ARTICE® treatment in the ICU
This study is collecting real-world data on ARTICE® treatment for adults in the ICU. It helps doctors understand how this treatment works in daily practice.
MagdeburgAges 18 years+ - NCT04855786Recruiting
Drain lymph fluid to reduce inflammation in septic shock
This study tests whether draining fluid from a chest lymph channel can lower inflammation chemicals (cytokines) in people with septic shock. It’s done using a procedure and aims to see if this helps stabilize the body’s inflammatory response.
Philadelphia, PennsylvaniaAges 18–80 - NCT06145828Recruiting
Testing a blood filter for severe pneumonia or sepsis in AIDS patients
This study tests a technique that filters harmful substances from the blood of people with AIDS who have severe pneumonia or septic shock. The goal is to see if this filter helps them recover better.
Guangzhou, GuangdongAges 18–65 - NCT07597122Recruiting
Blood markers study in septic shock patients
This research study measures special blood markers (microRNAs) in patients with septic shock or critical illness to understand how the body responds to severe infection. Results may help doctors better diagnose and treat sepsis in the future.
BernAges 18 years+ - NCT07483710Recruiting
CT scan muscle test in ICU for septic shock
This study looks at whether a CT scan of the lower back muscle, taken when you first arrive in the intensive care unit for septic shock, can help predict recovery three months later. It may help doctors better understand how muscle health affects survival.
LyonAges 18 years+ - NCT06937918Recruiting
Fluid management guide for septic shock patients
This study tests a computer software that helps doctors decide how much fluid to give patients in septic shock. It aims to improve blood pressure and oxygen delivery without causing fluid overload.
Bangkok Noi, BangkokAges 18 years+ - NCT04288635Recruiting
Testing a nutrient supplement for energy problems in septic shock
This study looks at whether a metabolite (nutrient) supplement can help the body’s cells work better when someone is in septic shock. It is done in the ICU, and it may benefit people with sepsis who still have poor circulation and high lactate levels despite standard treatment.
Angers, Maine et LoireAges 18 years+ - NCT03547414Recruiting
Urine markers to predict kidney injury worsening in septic shock
This study tests whether two substances in urine (TIMP2 and IGFBP7) can help doctors predict which patients with sepsis-related kidney problems will get worse. If these markers work, doctors could identify high-risk patients earlier and treat them more aggressively.
AmiensAges 18 years+ - NCT04067674Recruiting
Study immune changes in adults with septic shock
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
LyonAges 18 years+ - NCT05093075RecruitingPhase 2
Plasma exchange for ICU patients with severe septic shock
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Calgary, AlbertaAges 16 years+ - NCT07582926Recruiting
Cortisol Levels and Outcomes in Critically Ill Infection Patients
This study examines how the body's stress hormone (cortisol) relates to survival in patients with severe blood infections in the ICU. Understanding this relationship may help doctors better predict and manage outcomes in critically ill patients.
AnkaraAges 18 years+ - NCT05990491Recruiting
Pituitary function after recovery from septic shock in ICU survivors
This study checks how well the pituitary gland (a small gland in your brain that controls hormones) works after you recover from a severe infection that caused dangerously low blood pressure (septic shock). It aims to see if the gland was affected during your ICU stay.
Lucknow, Uttar PradeshAges 18–80 - NCT06062303Recruiting
Capillary refill time to guide septic shock treatment
This trial tests a new way of giving fluids and medicines to people with septic shock. It focuses on a simple sign called capillary refill time (how fast color returns when you press a fingernail) to guide treatment, aiming to improve recovery.
ReimsAges 18 years+
Hear when a new Septic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 120 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.