Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06072430RecruitingPhase 3
Testing a new fluid for septic shock with low blood pressure
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
Chandler, ArizonaAges 18 years+ - NCT06545838Recruiting
Testing renin levels to predict septic shock severity
This trial checks if a blood test measuring renin (a kidney hormone) can help predict how severe septic shock will be and how well patients recover. It looks for early clues in ICU patients with sepsis.
MoscowAges 18 years+ - NCT05931601RecruitingPhase 3
Early blood-pressure support in the emergency department
This Phase 3 study tests whether starting a blood-pressure medicine earlier in the emergency room can improve outcomes for people with low blood pressure or shock. It focuses on patients who have already received enough IV fluids and meet specific blood pressure and lab findings.
CopenhagenAges 18 years+ - NCT07539883Recruiting
Septic Shock Treatment With Special Kidney-Filter Devices
This study looks back at how a special kidney filter called oXiris helped patients in the ICU who had septic shock (a life-threatening blood infection) and kidney failure. Researchers want to understand if this filter improved survival and recovery compared to standard treatment.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT04844801Recruiting
Prevent fast heart rhythms during sepsis shock with rate control drugs
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
ParisAges 18 years+ - NCT06670963RecruitingPhase 4
Epoetin alfa and iron for anemia in sepsis
This trial tests whether a combination of epoetin alfa (a medicine that boosts red blood cell production) and iron derisomaltose (an iron supplement) can safely treat anemia in people with sepsis or septic shock. It may help improve your energy and recovery.
KatowiceAges 18 years+ - NCT07136532Recruiting
Predicting fluid needs in children with septic shock using ultrasound
This study tests whether using ultrasound of the neck (carotid artery) and heart can help doctors know which children with septic shock need more fluids. It aims to make fluid treatment safer and more precise in the pediatric intensive care unit (PICU).
CairoAges 1 month–16 years - NCT07354568Recruiting
Mixed heart and blood vessel shock study
This study looks at people with a severe type of shock that affects both the heart and blood vessels, treated in the intensive care unit. It aims to understand how these patients recover and what factors impact their survival.
Amiens, SommeAges 18 years+ - NCT07179276Recruiting
Testing CO₂ gap to guide septic shock treatment
This trial checks if measuring the carbon dioxide gap (a sign of how well blood is flowing to organs) can help doctors improve treatment for people in septic shock. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AngersAges 18 years+ - NCT05383963Recruiting
Using ICU routine data to diagnose sepsis sooner
This study checks whether information collected routinely in the ICU can help doctors recognize sepsis or septic shock earlier. If it works, it may improve how quickly diagnosis happens and potentially outcomes for patients.
BerlinAges 18 years+ - NCT05057611Recruiting
Tested blood-pressure rescue strategy using skin refill time
This study looks at a specific resuscitation (rescue) approach for adults in septic shock, using a bedside skin test called capillary refill time. If you qualify, the goal is to see whether this approach better stabilizes your body and improves outcomes.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06657625Enrolling by invitation
Improving sepsis care in the emergency department
This trial looks at a new program to improve how doctors and nurses treat sepsis (a severe infection that can cause organ failure) in the emergency department. It aims to see if the program helps start the right treatments faster.
BrestAges 18 years+ - NCT05975671Recruiting
Survey in pediatric ICU to reduce upfront vancomycin use
This study is a survey and quality-improvement effort in participating children’s intensive care units. It aims to understand and change how doctors decide to start vancomycin (an antibiotic) when sepsis is suspected, to improve care and avoid unnecessary use.
Atlanta, GeorgiaAges Any age - NCT04750070RecruitingPhase 3
Treating shock in young children with severe malnutrition and diarrhea
This study tests a treatment approach to help children who are in “shock” (their body is struggling to maintain blood flow and oxygen) caused by diarrhea and severe undernutrition. It may help care teams stabilize children faster and improve outcomes.
DhakaAges 1 month–4.9 years - NCT05586282Recruiting
Study proteins that may worsen fluid leaks in shock
This trial studies specific body proteins to understand why fluid can leak from blood vessels during dangerous shock after infection or heart problems. If you (or your representative) qualify, your team will collect information and possibly samples to see whether these proteins relate to recovery and treatment response.
ParisAges 18 years+ - NCT05725837RecruitingPhase 2
Paroxetine for circulation problems in early septic shock
This Phase 2 trial tests whether paroxetine can improve heart and blood-flow function in adults with septic shock that started within the last 48 hours. If you’re eligible, you may be asked to take the study medicine soon after diagnosis to see if it helps your cardiovascular function.
Colatina, Espírito SantoAges 18 years+ - NCT06898723RecruitingPhase 4
Shenfu injection to prevent heart problems in sepsis
This trial tests whether Shenfu injection can help prevent heart muscle damage in people with septic shock. If you have septic shock, you may be able to join this study to see if this treatment helps protect your heart.
Wuhu, AnhuiAges 18 years+ - NCT07264543RecruitingPhase 2/Phase 3
Early methylene blue for blood flow in sepsis
This trial tests if giving methylene blue early can improve blood flow in patients with sepsis who still have low blood pressure despite fluids and are on high doses of noradrenaline. It aims to help stabilize their condition.
Curitiba, ParanáAges 18 years+ - NCT04931225RecruitingPhase 3
Landiolol for heart-rate and circulation problems in septic shock
This Phase 3 trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can improve blood circulation in adults with septic shock whose heart rate is too fast. Doctors will also check that the medication is safe in this critical-care setting.
ParisAges 18 years+ - NCT06226441Recruiting
Aminoglycoside antibiotics for sepsis with low kidney function
This study tests how well aminoglycoside antibiotics work in people with sepsis who also have low kidney function. It may help find the best way to treat serious infections in patients with kidney problems.
Larissa, ThessalyAges 18 years+ - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06723626Recruiting
Recovery blend for elderly sepsis patients
This study tests whether giving a special combination of hydrocortisone, vitamin C, and vitamin B1 helps older adults with sepsis recover better. It looks at how the treatment affects tiny blood vessels and overall survival.
Nanjing, JiangsuAges 60–85 - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age
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Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 120 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.