Clinical trials
Skeletal Muscle clinical trials
Below are recruiting skeletal muscle clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05775588Recruiting
Lung valve treatment for severe COPD
This study tests tiny valves placed in your airways to see if they improve your heart and muscle function over the long term. It's for people with severe COPD (chronic lung disease) and significant emphysema damage.
Beijing, Beijing MunicipalityAges 18–90 - NCT07847424Recruiting
Daily heat therapy for people reducing physical activity
This study tests whether daily heat therapy (sauna sessions) can help maintain fitness and health when people temporarily reduce their physical activity. If you are a healthy adult, you might be able to join and contribute to understanding how heat affects the body.
Provo, UtahAges 18 years+ - NCT07780513Recruiting
Genetics of muscle insulin resistance study
This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.
San Antonio, TexasAges 18–75 - NCT07771010RecruitingPhase 4
Comparing empagliflozin and metformin for muscle health in type 2 diabetes
This study tests two diabetes medications, empagliflozin and metformin, to see how they affect muscle energy use and blood flow in men with recently diagnosed type 2 diabetes. Participants will be followed at a diabetes clinic.
LjubljanaAges 18–75 - NCT07729072Recruiting
Olive leaf extract for better exercise results
This study tests whether taking olive leaf extract supplements can improve how your muscles respond to exercise training. It involves a training program and taking a daily supplement, and may help you build muscle more effectively.
LausanneAges 18–45 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07692308Recruiting
Muscle health study for sarcopenia prevention and treatment
This study looks at muscle changes in people with or at risk for sarcopenia (age-related muscle loss). It aims to find better ways to detect and manage sarcopenia using simple tests like muscle strength and body composition measurements.
Milan, MiAges 50 years+ - NCT06660706Recruiting
Exercise study for older adults with slow walking or weak grip
This study tests whether a supervised exercise program can help improve muscle strength and overall health in people aged 65 and older. It also looks for certain markers in the blood that may be linked to the benefits of exercise.
TaipeiAges 65 years+ - NCT06672497Recruiting
Testing a light sensor for muscle health in breast and gynecological cancer patients
This study uses a safe, non-invasive light sensor (near-infrared spectroscopy) to measure how well your muscles use oxygen. Researchers want to learn if this tool can help monitor muscle health in people with breast or gynecological cancer that has not spread to other parts of the body.
Greenville, South CarolinaAges 20 years+ - NCT07654946Recruiting
Taurine supplement and muscle endurance in healthy adults
This study tests whether taking a taurine supplement can help your muscles work longer before getting tired. Researchers will use a light sensor on your leg to see how muscles use oxygen.
Baton Rouge, LouisianaAges 18–40 - NCT06687343Recruiting
Do amino acids help maintain muscle in young men?
This study looks at how certain amino acids (building blocks of protein) help maintain muscle mass. Healthy young men eat a special diet and have their muscle protein production measured to see if non-essential amino acids matter for keeping muscles strong.
MaastrichtAges 18–35 - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT07500727Recruiting
Exercise and muscle health in older adults with MS
This trial tests how exercise affects muscle health in people aged 60 or older with multiple sclerosis. It may help you understand if a structured exercise program can improve your strength and mobility.
Oklahoma City, OklahomaAges 60 years+ - NCT04449198RecruitingEarly Phase 1
Study for mitochondrial and blood-vessel issues in type 1 diabetes
This early study looks at how a new approach may affect energy-making (mitochondria) and blood-vessel signaling in people with insulin-dependent type 1 diabetes. It may help researchers understand whether these pathways can be improved in type 1 diabetes.
Augusta, GeorgiaAges 18 years+ - NCT06486597Recruiting
Metabolism study in children with cerebral palsy
This study looks at how the body uses energy in children with cerebral palsy who have low muscle mass. It compares them to healthy children to understand metabolism better.
Copenhagen, Copenhagen ØAges 2–18 - NCT07341711Recruiting
Muscle Changes after Hybrid Exercise Training
This study looks at how a mix of different exercises changes your muscles over time. It may help if you are inactive and want to see how your body responds to a structured training program.
Trikala, ThessalyAges 30–50 - NCT07281651Recruiting
Understanding pain sensitivity in knee pain and fibromyalgia
This study looks at how the brain and nerves process pain in people with knee pain or fibromyalgia. It compares them to pain-free people to understand differences in muscle signals.
Derby, DerbyshireAges 40 years+ - NCT07251361Enrolling by invitation
Exercise program for heart failure with preserved ejection fraction
This study tests whether a special exercise program that combines different types of training (like aerobic, strength, and balance) can improve heart and muscle function, daily abilities, and quality of life in people with heart failure with preserved ejection fraction (HFpEF). You may benefit if your heart failure is stable and you are able to exercise safely.
Pamplona, NavarreAges 18 years+ - NCT06573086Recruiting
Resistance training, detraining, and retraining
This study looks at how your body responds to resistance training, a break from training, and then training again. It is for healthy adults who already completed a previous exercise study.
Jyväskylä, Central FinlandAges 18–50 - NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity
This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.
St Louis, MissouriAges 50–75 - NCT07082309Recruiting
How ketone drinks affect muscle protein in healthy adults
This trial tests whether a ketone monoester drink can change how your body builds muscle protein. It may help researchers understand if these supplements could benefit muscle health.
Exeter, DevonAges 18–40 - NCT07059637Recruiting
Clinic for muscle loss in COPD patients
This study tests a new clinic designed to help people with COPD who have lost muscle mass (sarcopenia). By using a CT scan done during your hospital stay, doctors can identify muscle loss and offer treatments to help you regain strength and function.
Cleveland, OhioAges 40 years+ - NCT07034170Enrolling by invitation
Muscle mass and recovery after cardiac arrest
This study looks at how muscle mass affects recovery after a cardiac arrest (when the heart stops). It is for people who stay on a breathing machine in the ICU for more than three days. Researchers will measure muscle to see if it helps predict recovery.
Taipei, TaipeiAges 18–99 - NCT06967220Enrolling by invitation
Inflammation's effect on muscle in hospitalized patients
This study tests whether inflammation affects muscle loss in older hospitalized patients who are malnourished. It could help find ways to protect muscle strength during a hospital stay.
CopenhagenAges 65 years+
Hear when a new Skeletal Muscle trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for skeletal muscle?
- Yes. Clin2 currently lists 66 recruiting skeletal muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a skeletal muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a skeletal muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.