Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06571929Recruiting
Augmented reality training for arm function in children with cerebral palsy
This study tests whether playing special augmented reality games (where virtual objects appear in the real world) can improve arm and hand function in children with spastic cerebral palsy. It compares game training to usual therapy.
São Carlos, São PauloAges 6–12 - NCT07744659Recruiting
Spinal cord stimulation for stroke-related muscle stiffness
This trial tests a spinal cord stimulator to reduce muscle stiffness (spasticity) after a stroke. If you've had arm or leg tightness that hasn't improved with other treatments, this device might help you move more easily.
BeijingAges 18–75 - NCT07747961Recruiting
Virtual reality games for children with cerebral palsy
This trial tests whether playing virtual reality games, designed as part of a rehab program, can help improve movement and daily skills in children with a specific type of cerebral palsy (spastic diplegia). It may be a fun and engaging way to support physical therapy.
IslamabadAges 7–15 - NCT07747974Recruiting
Therapy for spastic cerebral palsy in children
This study compares two types of hand and arm therapy to help children with spastic cerebral palsy use their affected side better. Children will either practice with the affected hand through special exercises or use mirror therapy, which uses a mirror to create the illusion of movement.
IslamabadAges 5–9 - NCT07730086Recruiting
Using smartphones to study walking in children with cerebral palsy
This trial uses a smartphone app to measure how children with cerebral palsy walk. It aims to see if phone sensors can help doctors better understand gait problems.
Minya, Menia GovernorateAges 6–12 - NCT07715006Recruiting
Spinal nerve stimulation for children with cerebral palsy
This study adds a mild electrical stimulation to the spinal nerves during a planned SDR surgery for children with cerebral palsy, to see if it helps improve movement more than the surgery alone.
Pittsburgh, PennsylvaniaAges 3–14 - NCT07704840RecruitingPhase 2
Testing a new pill for post-stroke arm stiffness
This study tests an experimental pill (BMS-986368) that targets two brain chemicals to reduce muscle stiffness after a stroke. It's for people who had a stroke in the last 4 to 18 months and have moderate tightness in their elbow and wrist.
Elkins Park, PennsylvaniaAges 18–80 - NCT07694804Recruiting
Physical therapy for arm and hand function in children with cerebral palsy
This study tests two types of physical therapy to help children with spastic diplegic cerebral palsy improve the use of their arms and hands. The treatments focus on stretching and coordination exercises, and they may help your child with daily activities.
Mansehra, KPKAges 6–12 - NCT07685327Recruiting
Mixed reality vs. physical therapy for balance in teens with cerebral palsy
This study compares two types of therapy to help teens with spastic diplegic cerebral palsy improve their balance and coordination. One group will use mixed reality (a blend of real and virtual environments) and the other group will do standard physical therapy exercises.
Mansehra, KpkAges 10–19 - NCT06674057Recruiting
Taping with physical therapy for arm function after stroke
This study tests whether adding kinesio-taping to standard physical therapy helps improve arm movement and reduce stiffness in people recovering from a recent stroke.
IslamabadAges 40–65 - NCT06686719Recruiting
Stretching and relaxation for kids with spastic cerebral palsy
This trial compares three gentle stretching and muscle relaxation techniques to see which one best helps children with spastic cerebral palsy move more easily and feel less stiff. The goal is to find a safe, non-invasive way to improve daily function.
RawalpindiAges 8–18 - NCT06229626Recruiting
Intensive home training for hereditary spastic paraparesis SPG4
This trial tests an intensive, video-based exercise program for people with a specific type of hereditary spastic paraparesis (SPG4). It aims to see if adding extra training at home can improve walking and strength.
ParisAges 18 years+ - NCT02535936Recruiting
Brain plasticity study after rhizotomy surgery for spastic diplegia
This study looks at how the brain adapts after selective dorsal rhizotomy surgery in children with spastic diplegia. It may help doctors better understand recovery and treatment effects over time.
Houston, TexasAges 3–18 - NCT07561359Enrolling by invitation
12-Week Home Exercise Program for Hereditary Spastic Paraplegia
This trial tests whether a guided 12-week strength and movement exercise program, done at home using your phone or computer, can improve walking ability and muscle strength in people with hereditary spastic paraplegia (a genetic condition that causes leg stiffness and weakness). The program is tailored to your current fitness level.
Porto Alegre, Rio Grande do SulAges 16–70 - NCT05649930Recruiting
Power training for tight calf muscles in children with spastic paresis
This trial tests whether a specific exercise program that strengthens leg muscle power can improve calf muscle length and strength in children with spastic paresis (stiffness from the brain or nerves). If it works, it may help children move more easily and build stronger calves.
AmsterdamAges 4–18 - NCT07501429RecruitingPhase 1
Shockwave therapy for arm spasticity after spinal cord injury
This trial tests whether shockwave therapy can reduce muscle tightness in the elbow and wrist caused by spinal cord injury. It may help make daily tasks like dressing or bathing easier.
West Orange, New JerseyAges 18 years+ - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT07478822RecruitingPhase 3
Botulinum toxin study for arm spasticity after stroke
This study tests a new botulinum toxin injection (YY001) for adults whose arm muscles are tight or stiff after a stroke. It looks at whether repeated treatments help with daily activities like washing and dressing.
BeijingAges 18–75 - NCT06742697Recruiting
Exercise program to improve walking in Hereditary Spastic Paraplegia
This study tests a combined exercise program with flexibility, strength, aerobic, and movement training to see if it helps improve walking in adults with Hereditary Spastic Paraplegia. Participants attend at least 10 supervised sessions over several weeks.
Bosisio Parini, LombardyAges 18 years+ - NCT07447934Recruiting
Vibration therapy for leg muscle stiffness
This trial tests if gentle vibrations can reduce muscle stiffness (spasticity) in the lower leg after a neurologic condition like stroke or brain injury. You may join if you've had spasticity for at least 6 months and can stand with or without help.
New York, New YorkAges 18–85 - NCT07438223Recruiting
Brain gym exercises for balance in children with spastic diplegia
This study tests whether simple 'brain gym' exercises can help children with spastic diplegia (a type of cerebral palsy) improve their balance and quality of life. It could be a good option if you have mild muscle stiffness and are between 6 and 8 years old.
Cairo, Faculty of Physical TherapyAges 6–8 - NCT06270550Recruiting
Movement therapy for children with spastic diplegia
This study tests a movement therapy called Dynamic Movement Intervention to help children with spastic diplegia (a type of cerebral palsy) improve their walking and balance. It may be a good fit if your child is between 4 and 7, can walk short distances, and has mild muscle tightness.
CairoAges 4–7 - NCT06676332Recruiting
Training to improve movement and coordination in children with cerebral palsy
This trial tests whether a special training that combines mental imagery and sensory activities can improve muscle strength and coordination in children who have tight muscles in their legs. It is for children who can walk on their own or with some help.
CairoAges 8–12 - NCT06598657Recruiting
Gentle ankle mobilization for spastic cerebral palsy
This study tests a gentle ankle movement therapy to improve walking in children with spastic cerebral palsy. It may help reduce leg stiffness and make walking easier.
Islamabad, Punjab ProvinceAges 8–18
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 153 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.