Clinical trials · Illinois
Stroke clinical trials in Illinois
We’re tracking 55 recruiting stroke studies with a site in Illinois — including Early Phase 1, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT05479006Recruiting
tDCS for arm weakness after stroke
This trial tests whether a targeted, noninvasive brain stimulation (tDCS) can improve arm weakness and movement after stroke. It may help people who have significant trouble moving one arm on the side affected by stroke.
Urbana, IllinoisAges 18–90 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Evanston, IllinoisAges 1–120 - NCT05194566Recruiting
Brain stimulation for long-term speech trouble after stroke
This study tests whether a form of brain stimulation can improve naming words in people who still have language problems (aphasia) more than 6 months after a stroke. It may help people find and say words more accurately during a naming task.
Chicago, IllinoisAges 18–80 - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT04219670Recruiting
Using sensors to study stroke recovery in hospital and community
This study uses sensor recordings to learn how stroke recovery happens over time, including for people in the hospital and those living in the community. Your results may help improve future monitoring and rehabilitation after stroke.
Chicago, IllinoisAges 18 years+ - NCT04957355Recruiting
NMES therapy to improve balance and reduce falls after stroke
This trial tests whether NMES (a small electrical stimulation you feel on the skin) can improve balance and lower fall risk in people with stroke-related weakness. It may help you walk more steadily and safely, while the study measures balance and fall-related outcomes.
Chicago, IllinoisAges 18–90 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Chicago, IllinoisAges 18 years+ - NCT04477330Recruiting
Brain stimulation to improve walking after a stroke
This study tests whether a brain stimulation method (“cortical priming”) can improve walking after a stroke. It may help people with ongoing walking problems improve gait and leg control over a rehabilitation program.
Chicago, IllinoisAges 18 years+ - NCT04312269Recruiting
Brain stimulation plus memory practice to improve stroke arm recovery
This trial tests whether a combined therapy—MyoCI plus memory “reactivation”—can improve arm movement recovery after stroke. It’s meant for people with ongoing arm weakness at least 6 months after their first stroke.
Chicago, IllinoisAges 21–100 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Elk Grove Village, IllinoisAges 18–70 - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT03300141Enrolling by invitation
Robotic arm training with visual feedback after stroke
This trial tests a robotics-based training program that helps people practice reaching with both the arm and hand, using real-time visual guidance. It may help improve how smoothly and accurately you can reach after stroke.
Chicago, IllinoisAges 18 years+ - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+ - NCT06656754RecruitingEarly Phase 1
IsoReach: A study on reaching after stroke
This trial tests a new way to measure how people reach for objects, looking at differences between healthy adults and those who have had a stroke. The goal is to understand how stroke affects movement so better therapies can be developed.
Chicago, IllinoisAges 18 years+ - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Winfield, IllinoisAges 18–80 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Chicago, IllinoisAges 18 years+ - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT07061691Recruiting
Walking aid trial for stroke, Parkinson's, MS, or older adults
This trial tests a soft robotic suit (WIM Exosuit) to help people walk better. It may be an option if you have had a stroke, have Parkinson's or multiple sclerosis, or are an older adult without a neurological condition.
Chicago, IllinoisAges 18–89 - NCT06990867RecruitingPhase 2/Phase 3
Improving blood flow recovery after stroke
This trial tests a new approach to restore blood flow in the brain after a stroke. It aims to improve recovery and brain function in people with a blocked large artery.
Chicago, IllinoisAges 18–90 - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Chicago, IllinoisAges 18–70 - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Park Ridge, IllinoisAges 22–85 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Chicago, IllinoisAges 18 years+ - NCT06234124Recruiting
A shoe to improve walking after stroke
This study tests a special shoe that changes friction to help improve walking for people who have had a stroke. It lasts 6 months and involves daily exercises at home.
Chicago, IllinoisAges 18 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
Chicago, IllinoisAges 18–100
Stroke trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting stroke studies listed above.
- Shirley Ryan AbilityLab · 6 studies
- Northwestern University · 4 studies
- University of Chicago · 3 studies
- University of Chicago Medical Center · 3 studies
- Rush University Medical Center · 2 studies
- University of Illinois at Chicago · 2 studies
- University of Illinois Chicago · 2 studies
- Advocate Aurora Research Institute
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Illinois?
- Yes. We're currently tracking 55 recruiting stroke studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.