Clinical trials · Illinois
Stroke clinical trials in Illinois
We’re tracking 55 recruiting stroke studies with a site in Illinois — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
Chicago, IllinoisAges 18 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Chicago, IllinoisAges 18 years+ - NCT06386874Recruiting
Magnetic field therapy for arm recovery after stroke
This study tests a new magnetic device applied to the head to help improve arm function after a stroke. You will use the device while doing exercises, and a caregiver will support you with a mobile app and video calls.
Chicago, IllinoisAges 22–80 - NCT06598150Recruiting
Brain mapping study for chronic arm weakness after stroke
This study uses MRI scans to understand how the brain controls arm movement in people who have had a stroke. It aims to help develop better rehabilitation therapies for chronic arm weakness.
Chicago, IllinoisAges 18 years+ - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06655636Recruiting
Testing a new robotic brace to help stroke survivors open their hand
This trial tests a wearable robotic device (ExoNET) that helps stroke survivors with hand weakness. It aims to see if the device is safe and helpful for people who had a stroke at least 8 months ago and still have trouble using their arm and hand.
Chicago, IllinoisAges 40–70 - NCT06950593Recruiting
Electrical stimulation for arm recovery after stroke
This trial tests if a mild electrical current applied to the skin can help improve arm function in people who had a stroke at least 6 months ago. It is for those with significant arm weakness who are not currently in regular therapy.
Chicago, IllinoisAges 18 years+ - NCT07041775Recruiting
MINT video game training to improve walking after stroke
This study tests a new video-game–style training called MINT to help people who have had a stroke walk better. If you have trouble walking because one leg is weaker or slower than the other, this training might help improve your balance and coordination.
Chicago, IllinoisAges 18–85 - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+ - NCT07652970Recruiting
Home video therapy for severe stroke recovery
This study tests whether a new therapy done at home via video calls can help people with severe, long-lasting stroke regain leg movement and walking ability. If you have trouble walking or moving your leg on one side, this may be an option.
Chicago, IllinoisAges 18–80 - NCT03300141Enrolling by invitation
Robotic arm training with visual feedback after stroke
This trial tests a robotics-based training program that helps people practice reaching with both the arm and hand, using real-time visual guidance. It may help improve how smoothly and accurately you can reach after stroke.
Chicago, IllinoisAges 18 years+ - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Chicago, IllinoisAges 18–70 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Chicago, IllinoisAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Park Ridge, IllinoisAges 22–85 - NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Carbondale, IllinoisAges 18 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Chicago, IllinoisAges 18 years+ - NCT05180786Recruiting
Brain-training therapy to improve arm movement after stroke
This study tests a learning-and-recovery approach meant to help people regain arm and hand control after a long-term stroke. It targets patients with specific movement and brain-connection patterns so the training can be safely done.
Chicago, IllinoisAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Rock Island, IllinoisAges 18 years+ - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Park Ridge, IllinoisAges 18–80 - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
Chicago, IllinoisAges 18–100 - NCT06234124Recruiting
A shoe to improve walking after stroke
This study tests a special shoe that changes friction to help improve walking for people who have had a stroke. It lasts 6 months and involves daily exercises at home.
Chicago, IllinoisAges 18 years+ - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Chicago, IllinoisAges 18 years+ - NCT06656754RecruitingEarly Phase 1
IsoReach: A study on reaching after stroke
This trial tests a new way to measure how people reach for objects, looking at differences between healthy adults and those who have had a stroke. The goal is to understand how stroke affects movement so better therapies can be developed.
Chicago, IllinoisAges 18 years+
Stroke trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting stroke studies listed above.
- Shirley Ryan AbilityLab · 7 studies
- University of Chicago · 6 studies
- University of Illinois · 4 studies
- Northwestern University · 3 studies
- Rush University Medical Center · 3 studies
- Advocate Aurora Research Institute · 2 studies
- Advocate Health
- Advocate Lutheran General Hospital
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Illinois?
- Yes. We're currently tracking 55 recruiting stroke studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.