Clinical trials
Thyroid clinical trials
Below are recruiting thyroid clinical trials, each written for real people, not researchers. We’re tracking 324 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05604963Recruiting
Half or full thyroid surgery for low-risk thyroid cancer
This study looks at people with low-risk thyroid cancer who have already had (or are about to have) surgery, comparing half-thyroid removal versus full-thyroid removal. It may help doctors choose the safest and most effective surgery for your cancer type and risk level.
Crewe, CheshireAges 16 years+ - NCT05501041Enrolling by invitation
Testing symptom relief after thyroid radiofrequency ablation
This study looks at how well symptoms improve after a procedure called radiofrequency ablation (RFA) for thyroid nodules. It may help doctors better understand what kind of symptom relief to expect after the procedure.
Rochester, MinnesotaAges 18 years+ - NCT05189314Recruiting
Study of life quality changes with benign thyroid nodules
This study looks at how benign (non-cancer) thyroid nodules affect people’s day-to-day life and health outcomes. It may help doctors better understand what changes matter most to patients.
New York, New YorkAges 18 years+ - NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT05172921Recruiting
Study of environmental factors in thyroid cancer risk
This study looks at how environmental exposures may relate to thyroid cancer. If you have a suspicious thyroid nodule and are planning surgery, your biopsy or surgical tissue may be used to understand risk factors.
New York, New YorkAges 18 years+ - NCT05189821Recruiting
Study treatment for tiny thyroid cancer without surgery
This trial studies a treatment option for papillary thyroid microcarcinoma in adults who either do not want surgery or cannot safely have surgery. It may help people find a non-surgical approach for a very small thyroid cancer.
New York, New YorkAges 18 years+ - NCT04927416RecruitingPhase 2
Ga-DOTATATE PET/CT scan in metastatic thyroid cancer
This study tests whether a specific special scan (68-Gallium DOTATATE PET/CT) can help doctors better see where thyroid cancer has spread. It focuses on certain types of thyroid cancer and compares how well the scan images metastases.
Bethesda, MarylandAges 18–98 - NCT04892303RecruitingPhase 1
Planning treatment using radiation plus radioactive iodine for thyroid cancer
This Phase 1 study tests how doctors plan a combination of two radiation approaches—external beam radiation and radioactive iodine—for thyroid cancer that is not fully responding to standard treatment. It may help people who still have iodine-avid tumor spots, but whose iodine uptake looks too low to work well with radioactive iodine alone.
Baltimore, MarylandAges 18–85 - NCT04571736Recruiting
Web and video support during thyroid surgery planning
This study tests a pre-surgery video support program and a secure website to help people prepare for thyroid surgery. It may improve understanding and follow-through by collecting your answers before the operation.
Montpellier, HéraultAges 18–75 - NCT04589624RecruitingPhase 1
MRI scan to monitor response in head and neck cancers
This Phase 1 study tests an investigational MRI scan (hpMRI) to help doctors see how thyroid cancer and other head-and-neck cancers respond to treatment like radiation or other medicines. If you’re eligible, the scan may help track treatment effects more closely, though it’s still being studied for this purpose.
Houston, TexasAges 18 years+ - NCT03892993Recruiting
Decision aid for medullary thyroid cancer treatment choices
This study tests a patient-and-caregiver decision guide to help you decide when to start or stop a new cancer drug, join a clinical trial, or continue active surveillance. It aims to make tough choices feel clearer and more supported.
Houston, TexasAges 18 years+ - NCT03765333Recruiting
Registering people with thyroid cancer for a study
This study is a registry that collects information about adults with certain types of thyroid cancer. It may help researchers learn more about these cancers and how people are doing over time.
Barcelona, BarcelonaAges 18 years+ - NCT03099356RecruitingPhase 2
Cyclophosphamide and sirolimus for thyroid cancer that won’t respond to iodine
This trial tests whether the combination of cyclophosphamide and sirolimus can slow or shrink metastatic thyroid cancer that does not respond to iodine-131. It may help people whose cancer can’t be cured with surgery or other standard options and is still growing.
Ann Arbor, MichiganAges 18 years+ - NCT02747888Recruiting
Study of inherited risk for thyroid cancer
This study looks at whether thyroid cancer or thyroid lumps can run in families due to inherited (genetic) risk. It may help researchers better identify who is at higher risk and guide future screening or prevention.
Boston, MassachusettsAges Any age - NCT02609685Recruiting
Active monitoring for tiny papillary thyroid cancer
This study looks at whether closely watching (without immediate surgery or treatment) a very small thyroid cancer can be safe. You may benefit by avoiding unnecessary procedures, while the team monitors your thyroid and any changes over time.
Los Angeles, CaliforniaAges 18 years+ - NCT01511393Enrolling by invitation
Tracking people with thyroid cancer to learn its course
This study follows adults who have medullary thyroid cancer (MTC) to learn how the cancer behaves over time. It may help by improving future care and follow-up strategies for people with MTC.
Morgantown, West VirginiaAges 18 years+ - NCT01109420Recruiting
Family study of non-medullary thyroid cancer and genetics
This study looks at families affected by non-medullary thyroid cancer to understand patterns and possible genetic risk. You may be able to join even if you personally do not have the cancer, as long as you have the right family history and can complete a questionnaire.
Bethesda, MarylandAges 7–90 - NCT07879404Enrolling by invitation
Cold water spray for throat pain and thirst after thyroid surgery
This trial tests whether using a cold water spray can help reduce swallowing difficulty, pain, and thirst after thyroid surgery. It may provide a simple, non-medication way to feel more comfortable during recovery.
Ankara, AnkaraAges 18 years+ - NCT06239194RecruitingPhase 1/Phase 2
MdX2001 for advanced solid tumors
This trial tests a new drug, MDX2001, for people with advanced solid tumors that have spread. The study aims to find the best dose and see how well it works.
Denver, ColoradoAges 18 years+ - NCT03050762Recruiting
Collecting and following up on endocrine disease at MD Anderson
This study gathers medical information from people being seen for thyroid, parathyroid, or adrenal conditions at MD Anderson and checks in over time. It also asks family members of participants who pass away for permission to learn the cause of death, which may help researchers understand links to endocrine disease.
Houston, TexasAges Any age - NCT05112211Recruiting
Imaging study of doxycycline in thyroid eye disease
This study looks at how doxycycline (an antibiotic) affects thyroid eye disease using special imaging pictures. It may help doctors better understand disease activity and how well treatments work.
Guangzhou, GuangdongAges 18–70 - NCT05316922RecruitingPhase 3
Lowering thyroid hormone during radiation to prevent low thyroid
This study tests whether using treatment to keep thyroid-stimulating signals low during radiation to the thyroid area can help prevent a treatment-related drop in thyroid function in children. It is aimed at kids with certain cancers whose radiation plan includes thyroid tissue.
MilanAges Any age - NCT07870148Recruiting
Breast cancer and thyroid antibodies study
This study looks at whether the body's immune response to the thyroid is linked to breast cancer. It may help doctors understand how breast cancer behaves and how to treat it better.
MilanAges 18–80 - NCT07864155Recruiting
Pain relief without opioids for thyroid surgery
This study compares two ways to manage pain during and after thyroid surgery: one uses opioid painkillers, the other uses non-opioid medicines. The goal is to see if avoiding opioids can still provide good pain control and fewer side effects.
MalatyaAges 18–65
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Common questions
- Are there clinical trials for thyroid?
- Yes. Clin2 currently lists 324 recruiting thyroid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.