Clinical trials
Papillary Thyroid Carcinoma clinical trials
Below are recruiting papillary thyroid carcinoma clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+ - NCT03866382RecruitingPhase 2
Immunotherapy plus a targeted drug for rare genitourinary tumors
This Phase 2 study tests whether nivolumab and ipilimumab (immunotherapy drugs) plus cabozantinib (a targeted anti-cancer drug) can shrink or control rare cancers of the urinary/reproductive system that have spread. It may help by boosting the immune system and blocking cancer growth signals at the same time.
Birmingham, AlabamaAges 18 years+ - NCT04981509RecruitingPhase 2
Check if 3 medicines help advanced kidney cancer
This Phase 2 trial tests whether combining bevacizumab, erlotinib, and atezolizumab can shrink or control advanced kidney cancer. It’s aimed at people with certain kidney-cancer subtypes (including HLRCC-related cases or papillary kidney cancer) and who have not had many prior targeted or immune treatments.
La Jolla, CaliforniaAges 12 years+ - NCT05575440Recruiting
Testing an iodine-like PET/CT scan for thyroid cancer
This study checks how well a new PET/CT scan (18F-TFB) can find thyroid cancer after a standard iodine whole-body scan. It may help doctors see where the cancer is using an added imaging test, which could improve planning for care.
Rochester, MinnesotaAges 18 years+ - NCT05668962RecruitingPhase 2
Study selpercatinib plus I-131 for RET thyroid cancer that cannot take iodine
This trial tests whether combining a targeted pill (selpercatinib) with a radioactive iodine dose (I-131) can shrink thyroid cancer that has spread and no longer responds to radioactive iodine. It is for RET fusion–positive (genetically driven) thyroid cancers where the cancer cannot reliably absorb iodine anymore.
Washington D.C., District of ColumbiaAges 12 years+ - NCT05962892Recruiting
Study of thyroid cancer return risk after heat ablation
This study looks at what makes papillary thyroid cancer come back after a heat-based treatment called thermal ablation. It may help doctors better predict recurrence risk and guide follow-up after treatment.
BeijingAges 18 years+ - NCT06087068RecruitingPhase 2
Thyroid hormone therapy after lobectomy for low-risk thyroid cancer
This trial is testing whether thyroid hormone replacement after surgery is safe for people with low-risk papillary thyroid cancer. It may help maintain normal hormone levels after part of the thyroid is removed.
Beijing, Beijing MunicipalityAges 1.5 years–70 years - NCT06316895Recruiting
Thermal ablation for small, low-risk thyroid cancer
This trial is studying a treatment called thermal ablation (using heat to destroy cancer cells) for people with small, low-risk papillary thyroid cancer. It aims to see how well it works and to predict outcomes.
BeijingAges 18–80 - NCT06440850RecruitingPhase 2
Targeted therapy for high-risk BRAF-mutated thyroid cancer
This trial tests two targeted drugs, vemurafenib and cobimetinib, for people with high-risk thyroid cancer that has a specific BRAF V600E mutation. The goal is to see if this combination can help prevent the cancer from coming back after surgery or other initial treatments.
Duarte, CaliforniaAges 18 years+ - NCT07545837Recruiting
Wellness Coaching for Thyroid Cancer Survivors
This study tests whether personalized health coaching helps thyroid cancer survivors stick to their treatment plans and build healthier habits. You'll work with a coach to improve your overall wellness after thyroid cancer treatment.
Jacksonville, FloridaAges 18 years+ - NCT06733740Recruiting
Ultrasound-guided heat treatment for small thyroid cancer
This trial tests a minimally invasive heat treatment (thermal ablation) guided by ultrasound for small papillary thyroid cancers. It may be an option for patients who want to avoid surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06959641RecruitingPhase 2
XL092 for advanced thyroid cancer that no longer responds to radioactive iodine
This trial is testing a new oral medication, XL092, for people with advanced thyroid cancer that has stopped responding to radioactive iodine therapy. The goal is to see if XL092 can slow or stop the cancer from growing.
Torrance, CaliforniaAges 18 years+ - NCT07033572Recruiting
Hybrid scope surgery and ablation for both sides of thyroid cancer
This study tests a combined approach—removing the main thyroid cancer with a tiny camera (endoscope) and using targeted heat to destroy a small nodule on the opposite side. It aims to treat both sides of the thyroid at once with less scarring and faster recovery.
Fuzhou, FujianAges 18–65 - NCT07068542Recruiting
New drug combo for advanced thyroid cancer
This trial tests a new drug called sacituzumab tirumotecan combined with immunotherapy for people with advanced thyroid cancer that cannot be removed by surgery or has spread. It aims to see if this combination can help shrink tumors or slow down the cancer.
Hangzhou, ZhejiangAges 18 years+ - NCT07140757Recruiting
Radiofrequency ablation for thyroid nodules and low-risk cancer
This trial tests radiofrequency ablation (a heat-based treatment) for people with non-cancerous or suspicious thyroid nodules, or small thyroid cancers. It may be an option if you are not a candidate for or choose not to have surgery.
Houston, TexasAges 18 years+ - NCT07218315Recruiting
Electric Pulse Treatment for Small Thyroid Cancers
This trial is testing a new, non-surgical treatment that uses short electric pulses to destroy small papillary thyroid cancers. It may be an option for people with small tumors that haven't spread.
Sarasota, FloridaAges 18 years+ - NCT07302672Recruiting
WeChat support for thyroid cancer patients after heat ablation
This study tests whether extra support through the WeChat app can help people with small papillary thyroid cancers recover better after a heat-based tumor treatment called thermal ablation. You'd use your smartphone to get check-ins and advice from the care team.
BeijingAges 16–60 - NCT07357571Recruiting
Can ultrasound help predict lymph node spread in early thyroid cancer?
This trial uses contrast-enhanced ultrasound before surgery to see if it can predict whether cancer has spread to lymph nodes in patients with early-stage papillary thyroid cancer. The goal is to improve treatment planning without unnecessary surgery.
Guangdong, GuangzhouAges Any age - NCT07376837Recruiting
Radiofrequency ablation for small low-risk thyroid cancer
This study tests whether radiofrequency ablation (a heat-based treatment applied through the skin) can safely and effectively cure small, low-risk papillary thyroid cancers. It is designed for people whose tumors are small, have not spread, and who either cannot have surgery or prefer not to.
Toronto, OntarioAges 18 years+ - NCT06261190Enrolling by invitation
Active monitoring for low-risk thyroid cancer
This trial tests whether it is safe to avoid immediate surgery and instead monitor small thyroid cancers that are considered low-risk. If you join, doctors will check regularly to make sure the cancer does not grow or spread.
Goyang-siAges 18 years+ - NCT02609685Recruiting
Active monitoring for tiny papillary thyroid cancer
This study looks at whether closely watching (without immediate surgery or treatment) a very small thyroid cancer can be safe. You may benefit by avoiding unnecessary procedures, while the team monitors your thyroid and any changes over time.
Los Angeles, CaliforniaAges 18 years+ - NCT00001160Recruiting
Study of thyroid lumps and thyroid cancer
This study looks at people who have or may have thyroid nodules (lumps in the thyroid gland in your neck) or thyroid cancer, as well as family members who may have inherited a higher risk. It aims to better understand and diagnose these thyroid problems.
Bethesda, MarylandAges 6 months–98 years - NCT06592755Recruiting
New scar-free thyroid surgery vs. standard surgery for thyroid cancer
This trial compares a new, scar-free surgery (done through a small cut near the collarbone) to the standard open surgery for people with a common type of thyroid cancer. It may be a good option if your cancer is small and hasn't spread.
Guangzhou, GuangdongAges 18–70 - NCT06623578Recruiting
Robotic vs. open surgery for thyroid cancer that has spread
This study compares a robotic surgery method using small incisions under the armpit with standard open surgery for papillary thyroid cancer that has spread to lymph nodes on one side of the neck. It aims to see which approach is better for removing cancer and recovery.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for papillary thyroid carcinoma?
- Yes. Clin2 currently lists 33 recruiting papillary thyroid carcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a papillary thyroid carcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a papillary thyroid carcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.