Clinical trials
Transfusion clinical trials
Below are recruiting transfusion clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05762510RecruitingEarly Phase 1
Testing a gene-based treatment for transfusion-dependent thalassemia
This early study tests the safety and potential benefit of the LentiRed gene-based drug in people with transfusion-dependent beta-thalassemia (TDT) who are planning an autologous stem cell transplant. It may help reduce the severity of anemia, but the main goal at this stage is to check safety and side effects.
Nanning, GuangxiAges 5–35 - NCT05991336Recruiting
Growth and development after gene therapy for beta-thalassemia in children
This study looks at how children with transfusion-dependent beta-thalassemia grow and develop after gene therapy. It compares children who have had gene therapy with those who have not, and also with healthy children of the same age and gender.
Tianjin, Tianjin MunicipalityAges 3–14 - NCT06254560RecruitingPhase 2
Rituximab for severe aplastic anemia with platelet transfusion problems
This study tests if the drug rituximab can help people with severe aplastic anemia whose bodies have stopped responding to platelet transfusions. It aims to see if rituximab can improve the body's ability to accept platelets again.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05008744Recruiting
Laser treatment for twin-to-twin transfusion using one shared placenta
This study tests a laser procedure that seals abnormal blood vessel connections in identical twins sharing one placenta (twin-to-twin transfusion syndrome). The goal is to improve outcomes by stopping unbalanced blood flow between the twins.
Seattle, WashingtonAges Any age - NCT07680803RecruitingPhase 2
Gene therapy for transfusion-dependent beta-thalassemia
This trial tests a one-time gene therapy using your own stem cells to help you produce healthy red blood cells and reduce or eliminate the need for regular blood transfusions. It is for people with transfusion-dependent beta-thalassemia who are between 3 and 35 years old.
Rome, LazioAges 3–35 - NCT06657391RecruitingPhase 2
Study of a new drug to prevent graft-versus-host disease in thalassemia patients
This trial tests a drug called an anti-CD25 antibody to see if it can prevent graft-versus-host disease (a condition where donor cells attack the body) in people with transfusion-dependent thalassemia who are getting a stem cell transplant from a partially matched or unrelated donor.
Maoming, GuangdongAges 3–20 - NCT07672275Recruiting
How blood transfusions affect stress markers in newborns
This study looks at how blood transfusions change stress-related substances in the blood of newborns. It might help doctors understand how transfusions affect babies in the NICU.
Graz, StyriaAges 5 minutes–5 months - NCT07661589Recruiting
Blood transfusion risks and cell saver in children's scoliosis surgery
This trial looks at how often blood transfusions are needed during scoliosis surgery in children and whether using a device that recycles lost blood (cell saver) can reduce that need.
TunisAges Up to 17 years - NCT06699901Recruiting
Antibiotic levels after major blood transfusion
This study measures how antibiotics work in patients who have had a massive blood transfusion. It aims to ensure the right dose of common antibiotics is being given.
Aurora, ColoradoAges 18 years+ - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT07328191Recruiting
Transfusion guided by quality of life for MDS or AML
This study is for people with MDS or AML who are not receiving treatment to cure the disease and need regular blood transfusions. It looks at whether using a quality-of-life questionnaire can guide transfusion decisions, to see if fewer transfusions can keep you feeling well.
NiceAges 18 years+ - NCT07190560Recruiting
Study of a treatment for newborns exposed to chikungunya
This trial tests a new treatment (PC-CHIK-V) for newborns whose mothers had chikungunya around the time of birth. The goal is to see if the treatment can prevent or reduce the infection in babies. Babies who are not treated will also be followed for comparison.
Saint-PierreAges birth–2 days - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT06829901Recruiting
Uterine entry technique in laser surgery for twin-to-twin transfusion syndrome
This study looks at how doctors enter the uterus during laser surgery to treat twin-to-twin transfusion syndrome (TTTS), a condition where blood flow between twins is unequal. The goal is to see if a certain entry method leads to better outcomes for the babies.
Houston, TexasAges 18 years+ - NCT06812507Recruiting
Umbilical cord blood transfer in very premature babies
This trial tests different ways of transferring blood from the umbilical cord to very premature babies (born at or before 32 weeks) to see if it can prevent complications of prematurity and improve their blood counts. It aims to find the best method for helping these vulnerable newborns.
AlexandriaAges 1 minute–2 minutes - NCT06792019RecruitingPhase 1/Phase 2
Study of CM313 injection for platelet transfusion resistance
This trial tests a new drug called CM313 to see if it can help people whose platelet transfusions stop working. It is for adults who need platelet transfusions and have developed antibodies against them.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04688736RecruitingPhase 2
Placebo vs allergy medicine to prevent transfusion reactions
This trial tests whether an allergy medicine (chlorpheniramine) can prevent allergic reactions during blood transfusions. You might be placed in either the medicine group or a placebo (inactive pill) group to compare side effects and reaction rates.
Hefei, AnhuiAges 18–65 - NCT06710418Recruiting
Comparing two red blood cell transfusion thresholds for people with high-grade myeloid neoplasms, AML or B-ALL
This study compares two different strategies for when to give red blood cell transfusions to people receiving intensive chemotherapy or stem cell transplant for high-grade myeloid neoplasms, AML or B-ALL. The goal is to see which approach better improves quality of life and daily function.
Seattle, WashingtonAges 18 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06363760Enrolling by invitation
Long-term follow-up after EDIT-301 gene therapy
This long-term follow-up study monitors people with sickle cell disease or transfusion-dependent beta-thalassemia who have already received the gene-editing therapy EDIT-301. It helps researchers understand how safe and effective the treatment is over time.
Oakland, CaliforniaAges 12–50 - NCT06012760Recruiting
Can iron and vitamin C reduce transfusions during heart surgery?
This trial is testing whether giving iron plus vitamin C before heart surgery can reduce the need for blood transfusions. It is for people with low iron and anemia who are scheduled for bypass or valve surgery.
Hangzhou, ZhejiangAges 18 years+ - NCT03999229RecruitingPhase 1
Nitric-oxide therapy during your own blood return
This early study tests whether a nitric-oxide–based treatment (given during autologous blood transfusion) can affect how well your body handles the returned blood. It mainly needs healthy adults who can safely donate blood and follow medication and breathing/comfort requirements.
Cleveland, OhioAges 18–35 - NCT05711485Recruiting
Platelet-directed whole blood transfusion for malaria in young children
This study is testing a new way to use whole blood transfusions to treat severe malaria in young children. It might help children with very low platelet counts and low hemoglobin recover better.
Baltimore, MarylandAges 1 month–4.9 years - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+
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Common questions
- Are there clinical trials for transfusion?
- Yes. Clin2 currently lists 122 recruiting transfusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transfusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transfusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.