Clinical trials
Traumatic Brain Injury clinical trials
Below are recruiting traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 361 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06992570Enrolling by invitation
Brain injury risk in military training
This trial studies the risk of mild traumatic brain injury during military training. It may help improve safety for service members by understanding when and how these injuries happen.
Prague, Czech RepublicAges 18–50 - NCT06981897Enrolling by invitation
Early cognitive rehab for moderate brain injury recovery
This trial tests whether starting cognitive rehabilitation early after a moderate traumatic brain injury helps improve thinking, memory, and daily function. If you're an adult with a moderate brain injury who is medically stable, this study may help you regain skills faster.
Cairo, ManialAges 18 years+ - NCT06901310Enrolling by invitation
Hyperbaric oxygen for mild head injuries in combat athletes
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) helps men recover from mild head injuries better than the current standard care (rest). It is for male unarmed combat athletes who have been suspended for a head injury.
Marshfield, WisconsinAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT06115291Enrolling by invitation
Smell training study for adults with smell loss
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Kansas City, KansasAges 18–80 - NCT05942638Enrolling by invitation
Tracking how concussion affects college driving over time
This study follows young adults who drive to see how a concussion may affect driving abilities over time. You may be asked to complete driving- and health-related assessments, and the results could help improve safety and guidance after concussion.
Athens, GeorgiaAges 18 years+ - NCT05929833Enrolling by invitation
Brain injury education program for recovery at home
This study tests a recovery-focused brain injury education and support program for people with traumatic brain injury (TBI) who plan to go home after hospital stay. If you qualify, you and a caregiver/friend may get training and therapy support aimed at improving recovery.
Durham, North CarolinaAges 18 years+ - NCT05917665Enrolling by invitation
Test biomarkers in special forces course instructors
This study looks for early body and brain “signals” (biomarkers) that may show how brain injury happens and how recovery works over time. It is only open to instructors of a specific Special Forces course.
Fort Bragg, North CarolinaAges 18 years+ - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
San Francisco, CaliforniaAges 18–65 - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT05527041Enrolling by invitation
Portable eye test device for mild concussion after injury
This study tests a portable device that uses eye checks to assess people with a mild concussion after a head or body impact. It may help find concussion-related changes in settings like deployment or far-forward locations.
West Point, New YorkAges 17–35 - NCT04982731Enrolling by invitation
Testing reassurance support after a concussion in teens
This study looks at whether a specific reassurance program (“Positive Assurance”) helps teens recover better after a mild concussion. Teens are checked for concussion symptoms, then assigned to different support approaches to see which helps most.
Falls Church, VirginiaAges 13–21 - NCT03502967Enrolling by invitationEarly Phase 1
Hyperpolarized carbon-13 brain scan for recent traumatic brain injury
This early study tests a special brain imaging scan that looks at brain metabolism after a recent concussion/traumatic brain injury (TBI). It may help researchers understand what’s happening in the brain soon after injury.
Dallas, TexasAges 18–60 - NCT07696598Recruiting
Brain bleed surgery study in children after head injury
This study looks at how children under 18 do after surgery for a specific type of brain bleed (called an extradural or epidural hematoma) caused by a head injury. The goal is to understand what helps them heal better.
Sohag, Sohag GovernorateAges 1 day–18 years - NCT07732868Enrolling by invitation
Virtual Reality Therapy for Spinal Cord Injury
This trial tests a virtual reality (VR) program that uses brain-machine interface (BMI) technology to help people with spinal cord injuries regain movement. The program may help your brain and body work together better, potentially improving your recovery.
AveiroAges 18–65 - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05993364Recruiting
EFA treatment for brain injury recovery
This trial tests a treatment called EFA for people recovering from a brain injury (from trauma or stroke). It aims to help patients who are still in the early stages of recovery and can breathe on their own during the day.
Rovato, BSAges 18 years+ - NCT07345481Recruiting
Learning new connections in brain injury
This study tests whether people with an acquired brain injury can learn new connections between symbols and words using a computer-based learning method. The goal is to see if this approach can help with cognitive rehabilitation.
Arnhem, GelderlandAges 18–75 - NCT06800040Enrolling by invitation
Group memory training for brain injury survivors
This trial tests a group memory training program for people who have had a brain injury at least 6 months ago and still have memory problems. The training is in Norwegian and aims to help improve memory skills.
TromsøAges 18–75 - NCT05863897Enrolling by invitation
Online program to help long-term fatigue after brain injury
This trial tests an online, blended coaching program for severe fatigue that lasts at least 6 months after a stroke or traumatic brain injury. It may help reduce fatigue by supporting self-management using an internet-based approach.
Wijk aan Zee, North HollandAges 18–70 - NCT05183152Recruiting
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT07166536Recruiting
Study on mental imagery and symptom worsening after concussion
This trial tests whether mental imagery tasks can trigger or worsen headaches and dizziness in people with long-lasting symptoms after a mild traumatic brain injury or concussion. If you still have headaches or dizziness more than 3 months after your injury, this study may help understand how your brain reacts to mental exercises.
Tel AvivAges 18–74
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Common questions
- Are there clinical trials for traumatic brain injury?
- Yes. Clin2 currently lists 361 recruiting traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.