Clinical trials
Treatment Failure clinical trials
Below are recruiting treatment failure clinical trials, each written for real people, not researchers. We’re tracking 140 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06930495Enrolling by invitation
Weight loss and heart failure with normal pumping strength
This study tests whether weight loss treatments can improve muscle and blood vessel function in people with a specific type of heart failure (HFpEF) who also have obesity. It may help if you have heart failure with a normal ejection fraction and a high BMI.
Dallas, TexasAges 18 years+ - NCT06652776Enrolling by invitation
Italian COPD patient registry study
This study is creating a registry to better understand Chronic Obstructive Pulmonary Disease (COPD) in Italian patients. It will collect information from people with COPD to improve care and research.
Milan, MilanAges 40 years+ - NCT06374589Recruiting
Closing the loop on oxygen use during high flow therapy
This trial tests a system that automatically adjusts oxygen levels for patients receiving high flow oxygen therapy. The goal is to see if it can keep oxygen levels in a safe range better than usual care.
IstanbulAges 18 years+ - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT07731490Recruiting
Early detection and treatment of heart failure
This trial tests if a medication can prevent heart failure in older adults who are at risk. It is for people aged 65 or older who are having certain heart procedures or a major surgery.
ViennaAges 65 years+ - NCT05343572RecruitingEarly Phase 1
Stem cell treatment to improve abnormal uterine lining
This early-phase study tests whether mobilized stem cells from bone marrow can help women with certain abnormal uterine lining problems become healthier and possibly improve fertility. It’s aimed at people who are not pregnant and meet specific diagnoses and test results.
Orange, ConnecticutAges 18–40 - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07131631Recruiting
MitraClip for leaky heart valve in heart failure patients
This trial tests if the MitraClip device helps people with heart failure and a leaky mitral valve. It uses a special MRI to check how the heart responds to treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT07422506Recruiting
Comparing treatments for early missed abortion
This study compares different treatment methods for early missed abortion (when a pregnancy ends but the tissue doesn't pass on its own) to see which works best in real-world settings. It may help you and your doctor choose the safest and most effective option.
Changsha, HunanAges 18–40 - NCT07535320Recruiting
What Dialysis Treatment Do Patients Prefer?
This research study asks patients with advanced kidney disease about their preferences for different dialysis treatment options before starting treatment. Your feedback helps doctors understand what matters most to patients when choosing how to manage their kidney disease.
CaenAges 18 years+ - NCT07109531RecruitingPhase 3
New drug combo for advanced lung cancer after TKI failure
This trial tests a combination of two experimental drugs (ASKC202 and limertinib) against standard chemotherapy for people with advanced non-small cell lung cancer that has a MET gene change and has stopped responding to earlier targeted therapy (EGFR-TKI). It aims to see if the new combination works better.
ShanghaiAges 18 years+ - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT06527963Recruiting
Balloon types for fistula narrowing in dialysis patients
This trial compares two types of balloons used to open up narrowed areas in the blood vessels of dialysis patients. It aims to find which balloon works better for keeping the fistula working well.
Zhengzhou, HenanAges 18–75 - NCT07108231Recruiting
Breathing muscle training for hospitalized heart failure patients
This trial tests whether training the muscles you use to breathe can help people recover while in the hospital for heart failure. If you are stable enough, you may be able to join.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06754475Recruiting
Low volume arm HIIT for heart failure patients
This trial tests if short, high-intensity arm exercises can help people with stable heart failure. It looks at safety and improvements in daily function.
Mersin, MersinAges 18 years+ - NCT07207811RecruitingPhase 3
Coramitug for heart failure caused by ATTR amyloidosis
This trial tests a new medicine called Coramitug for people with heart failure due to ATTR amyloidosis, a condition where abnormal proteins build up in the heart. The study aims to see if Coramitug can improve heart function and quality of life.
Phoenix, ArizonaAges 18 years+ - NCT07107100Recruiting
Comparing two types of retainers after braces
This study compares two types of retainers (a wire that keeps teeth in place) after braces are removed: one that is directly bonded to the teeth and one that is made indirectly. It looks at which type keeps gums healthy, lasts longer, and how likely it is to break.
Karachi, SindhAges 13–40 - NCT03547232RecruitingPhase 4
Indomethacin given early to treat acute pancreatitis
This trial tests whether taking indomethacin (an anti-inflammatory medicine) early can improve outcomes in people with acute pancreatitis. You might be eligible if your pancreatitis is diagnosed soon and you meet specific lab, imaging, and safety requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT03920618Recruiting
Testing three HBV medicines for severe liver flare (ACLF)
This study compares three hepatitis B (HBV) medicines to see which treatment helps people with a severe liver flare. You may be eligible if you have confirmed HBV and lab results showing significant liver stress.
Guangzhou, GuangdongAges 12–65 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT05696522Recruiting
Radiation to treat hard-to-control dangerous heart rhythm
This trial tests a focused type of radiation to treat ventricular tachycardia (VT) that keeps coming back despite other treatments. It may help people who cannot (or do not want to) have the usual catheter procedure to fix the rhythm.
LondonAges 18–85
Hear when a new Treatment Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for treatment failure?
- Yes. Clin2 currently lists 140 recruiting treatment failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.