Clinical trials
Treatment clinical trials
Below are recruiting treatment clinical trials, each written for real people, not researchers. We’re tracking 8,307 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05287126RecruitingPhase 2
Etrasimod for teens with active ulcerative colitis
This trial tests whether etrasimod can improve ulcerative colitis (UC) symptoms in adolescents with moderate to severe, active disease. It may help reduce inflammation and disease activity, especially if current treatments aren’t working well enough.
Little Rock, ArkansasAges 12–17 - NCT05266872Recruiting
Earlier diagnosis and better treatment study for Parkinson’s
This study is looking to improve how Parkinson’s and related brain conditions are identified and treated sooner. You may be asked to share your health information and provide blood or other samples, and possibly have procedures like a spinal fluid test or a small skin sample.
LuxembourgAges 18 years+ - NCT04434586Recruiting
Imaging test to guide treatment of blocked thigh arteries
This study tests whether a detailed eye-like scan (optical coherence tomography) helps doctors choose better treatment for blockages in the thigh-to-knee artery. It may help improve healing and outcomes by guiding how the procedure is done.
LilleAges 18 years+ - NCT04365998Recruiting
Testing a new light device for newborn jaundice
This study tests a new phototherapy (special light treatment) device to treat newborn jaundice. It may help by seeing whether this device can treat jaundice safely and effectively.
LilleAges Up to 4 weeks - NCT05248659Enrolling by invitationPhase 2/Phase 3
Sibeprenlimab for IgA kidney disease after prior study
This trial studies sibeprenlimab to see if it can improve IgA nephropathy, a kidney inflammation condition. You may be able to join if you finished a previous related Otsuka study without major safety problems and your doctor thinks you could benefit.
Birmingham, AlabamaAges 18 years+ - NCT05253651RecruitingPhase 3
Tucatinib plus trastuzumab with chemo for HER2+ metastatic colon cancer
This trial tests whether adding tucatinib and trastuzumab to standard chemotherapy works better than standard treatment alone for people with HER2-positive metastatic colon or rectal cancer. It aims to improve how long people live and how well tumors respond as first treatment for advanced disease.
Glendale, ArizonaAges 18 years+ - NCT05241262RecruitingPhase 1
N-acetylcysteine for people with m.3243A>G and low brain glutathione
This trial tests whether the supplement N-acetylcysteine (NAC) can help people who have the m.3243A>G mitochondrial genetic change and low levels of a brain chemical called glutathione. The study aims to see if raising glutathione in the brain is safe and potentially beneficial for these patients.
New York, New YorkAges 18–80 - NCT05231122RecruitingPhase 2
Pembrolizumab and bevacizumab for recurrent ovarian cancer
This trial studies whether adding pembrolizumab to bevacizumab (and sometimes an anti-CD40 drug) can help control recurrent ovarian, fallopian tube, or primary peritoneal cancer. It also looks at whether the treatment can shrink tumors and keep them from growing for longer.
Buffalo, New YorkAges 18 years+ - NCT05256641RecruitingPhase 1/Phase 2
Acalabrutinib maintenance after transplant or CAR T for large B-cell lymphoma
This trial studies acalabrutinib given after certain lymphoma treatments (like stem cell transplant or CAR T therapy) to help keep the lymphoma from coming back. It’s for people whose disease has shrunk (partial response) or fully gone away (complete response) after those treatments.
Los Angeles, CaliforniaAges 18–70 - NCT05248620Recruiting
Antibiotics to prevent infections in hemodialysis catheters
This trial tests whether taking preventive antibiotics (or a placebo sugar pill) can lower the risk of infections in people who receive hemodialysis through a catheter. It may help protect you from serious catheter-related infections, but you must be able to follow the study’s medicine and consent rules.
Copenhagen, Capital RegionAges 18 years+ - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT05242965RecruitingPhase 2
STEMVAC vaccine with pembrolizumab for advanced lung cancer
This trial tests a cancer vaccine called STEMVAC for people with advanced non-small cell lung cancer. The vaccine is given along with ongoing maintenance immunotherapy (pembrolizumab) to see if it can help keep the cancer from growing.
Omaha, NebraskaAges 18 years+ - NCT05241990Recruiting
Help improve alcohol care for people with HIV in clinics
This study tries a practical clinic strategy to help HIV clinics better offer and carry out alcohol treatment. You may be able to join if you work at the clinic or if you have HIV and your alcohol use screening shows possible unhealthy drinking.
San Diego, CaliforniaAges 18 years+ - NCT05248919Enrolling by invitation
Study treatment for hepatitis C that did not work before
This trial looks at hepatitis C treatment for people whose last antiviral medicines did not fully clear the virus. It may help by testing a study drug approach for people in Pakistan who still have active hepatitis C infection.
Karachi, SindhAges 18–100 - NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT05225363RecruitingPhase 1
CAR T therapy for ovarian cancer that no longer responds to platinum
This Phase 1 study tests a one-time treatment made from your immune cells (CAR T) to attack a protein found on some ovarian cancer cells. It is for people whose ovarian cancer has come back or worsened after platinum chemotherapy, aiming to see safety and early signs of benefit.
Duarte, CaliforniaAges 18 years+ - NCT05205317Recruiting
VR alone or VR plus metformin for C-section scar healing
This study compares two treatments to help improve a C-section scar defect (an issue seen on the uterus scar). Some participants may receive virtual reality (VR) therapy plus metformin, while others receive VR alone, and the researchers will look at symptoms and scar healing.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT05206682Recruiting
Treating C-section scar defect with hormones versus surgery alone
This trial compares two treatments for a pregnancy-related problem in the uterus: vaginal repair alone versus vaginal repair plus leuprorelin (a hormone medicine). It aims to improve symptoms like long or heavy bleeding when a C-section scar defect is also linked with adenomyosis.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT05240352Recruiting
Personalized brain stimulation help for bipolar depression anhedonia
This study looks at using brain scans to better tailor transcranial direct current stimulation (a noninvasive brain stimulation) for people with bipolar depression who feel little pleasure. It aims to see whether matching the stimulation to your brain signals can improve symptoms like anhedonia.
Houston, TexasAges 18–50 - NCT05224414Recruiting
Study of how thinking styles may affect OCD treatment response
This study looks at how your interpretation of unclear situations may influence how well OCD treatment works. You’ll likely complete a computer task to understand thinking patterns and response to the main OCD study protocol.
Belmont, MassachusettsAges 18 years+ - NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Scottsdale, ArizonaAges 18 years+ - NCT05231993Enrolling by invitation
Treats HPV-positive atypical cervical cells found on screening
This study is for women whose cervical screening shows atypical glandular cells and who test positive for HPV types 16 or 18. It aims to decide the best way to triage and manage these findings so people get the right follow-up and treatment.
StockholmAges 23–64 - NCT05234307RecruitingPhase 1
Nivolumab plus PBF-1129 for advanced lung cancer
This Phase 1 trial tests a new combination of PBF-1129 with nivolumab (an immune therapy) for lung cancer that has come back or spread. It aims to find a safe dose and see whether the combination can shrink tumors and improve outcomes.
Columbus, OhioAges 18 years+ - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99
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Common questions
- Are there clinical trials for treatment?
- Yes. Clin2 currently lists 8,307 recruiting treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.