Clinical trials · North Carolina
Type 2 diabetes clinical trials in North Carolina
We’re tracking 53 recruiting type 2 diabetes studies with a site in North Carolina — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Cary, North CarolinaAges 18 years+ - NCT07054125Recruiting
CGM, education, and peer support for type 2 diabetes
This trial tests if using a continuous glucose monitor (a small sensor that tracks your blood sugar), combined with diabetes education and support from others with diabetes, can help people with type 2 diabetes better control their blood sugar. You may qualify if your blood sugar is not well controlled (A1c above 8%).
Asheville, North CarolinaAges 18 years+ - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Durham, North CarolinaAges 18 years+ - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Durham, North CarolinaAges 18 years+ - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Morehead City, North CarolinaAges 18–75 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Greenville, North CarolinaAges 12–35 - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Chapel Hill, North CarolinaAges 10–17 - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
Chapel Hill, North CarolinaAges 18–50 - NCT06525259Recruiting
Study on risk factors for type 2 diabetes in youth
This study looks for children and teens who are at high risk of developing type 2 diabetes to understand what factors lead to it. If your child is overweight, has slightly high blood sugar, and is in early to mid-puberty, they may be able to join.
Charlotte, North CarolinaAges 8–15 - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Chapel Hill, North CarolinaAges Any age - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Charlotte, North CarolinaAges 40–80 - NCT05540704Recruiting
Therapy support for eating problems in type 1 diabetes
This study compares three groups: Acceptance and Commitment Therapy, standard supportive diabetes counseling, or a waitlist. It aims to reduce binge eating and harmful weight-control behaviors, including insulin withholding, in people with type 1 diabetes.
Durham, North CarolinaAges 16–50 - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
Asheville, North CarolinaAges 5–40 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Asheville, North CarolinaAges 1–25 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
Chapel Hill, North CarolinaAges 18–55 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Morehead City, North CarolinaAges 18–75 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Durham, North CarolinaAges 18–55 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Charlotte, North CarolinaAges 18–79 - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Statesville, North CarolinaAges 18 years+ - NCT07361341Recruiting
Food support program for adults with diabetes or prediabetes
This trial tests a culturally tailored food bundle program for people with type 2 diabetes or very high prediabetes who also face food insecurity. If you qualify, you may receive free food bundles and help managing your health.
Winston-Salem, North CarolinaAges 18 years+ - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Monroe, North CarolinaAges 18 years+ - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Greensboro, North CarolinaAges 18 years+ - NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Charlotte, North CarolinaAges 18 years+ - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+
Type 2 diabetes trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting type 2 diabetes studies listed above.
- Duke University Medical Center · 6 studies
- UNC Children's Hospital · 3 studies
- University of North Carolina at Chapel Hill · 3 studies
- Asheville Clinical Research · 2 studies
- Lucas Research, Inc. · 2 studies
- Wake Forest University Health Sciences · 2 studies
- Accellacare
- Accellacare of Piedmont, Piedmont Healthcare
What taking part in a type 2 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 2 diabetes trials in other states
Common questions
- Are there type 2 diabetes clinical trials in North Carolina?
- Yes. We're currently tracking 53 recruiting type 2 diabetes studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 2 diabetes study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 2 diabetes studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.