Clinical trials
Valve Heart Stenosis clinical trials
Below are recruiting valve heart stenosis clinical trials, each written for real people, not researchers. We’re tracking 137 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07045233Enrolling by invitation
Using a brain protection device during TAVR to prevent stroke
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
BeijingAges 18 years+ - NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Beijing, Beijing MunicipalityAges 65 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT07359898Recruiting
Study of a new heart valve for aortic stenosis
This study is testing a new type of heart valve (Navitor or Navitor Vision) for people with aortic stenosis. The valve is placed without open-heart surgery, and the goal is to see how well it works in a real-world setting. If you've already been recommended for this procedure by your heart team, you may be able to join.
San Donato Milanese, LombardyAges 18 years+ - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT07201363Recruiting
Inflammation and scarring markers after TAVI
This study looks at markers of inflammation and scarring in people who develop heart rhythm problems after having a TAVI procedure (a minimally invasive valve replacement). It may help doctors understand and predict these complications.
Rijeka, CroatiaAges 18 years+ - NCT07343674Recruiting
Studying a new heart valve replacement system for aortic stenosis
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Coimbra, Coimbra DistrictAges 18 years+ - NCT06861361Recruiting
Surgery versus transcatheter valve replacement in younger patients
This trial compares two ways to replace a narrowed aortic heart valve in patients aged 65 to 75. It aims to find which approach—surgical valve replacement or a catheter-based procedure—works better for people in this age group.
GrazAges 65–75 - NCT07055919Recruiting
Assist system for mitral valve clip procedure
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
Xiamen, FujianAges 18 years+ - NCT04552275RecruitingPhase 1
Biomarker study during valve replacement for older adults
This Phase 1 study looks at changes in the body’s “biomarkers” (measurable signs in blood/medical tests) in older people who are getting a specific type of valve replacement. Results may help doctors better monitor or understand outcomes after this valve procedure.
Boston, MassachusettsAges 65 years+ - NCT07278310Recruiting
Siegel Valve for Severe Aortic Stenosis (TAVR)
This study tests a new replacement valve called the Siegel, placed through a catheter in your leg (TAVR), for people with severe aortic stenosis. It aims to see if it is safe and effective for patients at low, intermediate, or high surgical risk.
Atlanta, GeorgiaAges 18 years+ - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT05452720Recruiting
Testing a new pulmonary valve replacement in children
This study tests an early, first-use version of a new pulmonary valve device for children whose own valve is not working well. It may help improve blood flow from the heart to the lungs and aims to learn how safe and effective the valve is over time.
Peoria, IllinoisAges birth–22 years - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT07095829Recruiting
Predicting circulation after birth for severe pulmonary valve blockage
This study looks at babies with a severe heart defect where the pulmonary valve is blocked and the wall between the heart's lower chambers is intact. It aims to predict how well blood will flow after birth using ultrasound images taken during pregnancy.
MadridAges 4 months–6 months - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+
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Common questions
- Are there clinical trials for valve heart stenosis?
- Yes. Clin2 currently lists 137 recruiting valve heart stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valve heart stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valve heart stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.