Clinical trials
Valvular Heart Disease clinical trials
Below are recruiting valvular heart disease clinical trials, each written for real people, not researchers. We’re tracking 117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04014140Recruiting
iFR-guided bypass surgery planning during elective heart surgery
This trial studies whether using a pressure-measurement test called iFR during a pre-surgery heart scan can help guide coronary artery bypass surgery (CABG). It may improve how doctors choose which artery blockages to treat during planned surgery.
London, Greater LondonAges 25–80 - NCT07238920Recruiting
Brain training for heart health in people with coronary artery disease and anxiety
This trial tests a brain-training technique called neurofeedback, which uses a video game controlled by your brain activity to help your heart and nervous system work better. It is for people with both coronary artery disease and anxiety who want to improve their heart health and manage anxiety without medication.
Shenyang, LiaoningAges 18 years+ - NCT07244484Recruiting
Brain Training for Heart Health in Coronary Artery Disease with Anxiety
This trial tests a brain training technique (neurofeedback) to help people with coronary artery disease and anxiety. It aims to improve heart rate control by targeting a specific brain area.
Shenyang, LiaoningAges 18 years+ - NCT04962711Recruiting
Risk-guided plan to prevent heart failure after cancer treatment
This trial tests whether a personalized, risk-based heart care plan can help prevent heart failure in people who had certain cancer treatments. It focuses on monitoring and guiding treatment, using heart ultrasound results and other health factors.
Melbourne, VictoriaAges 40–85 - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT07041359RecruitingPhase 4
Traditional Chinese medicine for elderly heart disease patients with ongoing symptoms
This trial tests whether traditional Chinese medicine can help elderly patients with coronary heart disease who still have chest pain or discomfort despite standard treatments. It focuses on those who cannot have or have not fully benefited from procedures like stents or bypass surgery.
Beijing, Beijing MunicipalityAges 75–90 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT03563417Recruiting
CTO treatment vs medicines after heart scan
This trial studies whether opening a blocked coronary artery (a CTO) helps people more than staying on the best available heart medicines after an initial 3-month treatment period. It uses heart imaging to confirm there is reduced blood flow in the area supplied by the blockage.
Aarhus NAges 18 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT05672706Recruiting
Pressure wave test for people with angina
This study looks at how a pressure waveform in the heart’s blood vessels can be analyzed to learn more about angina (chest discomfort from reduced blood flow). You may be asked to undergo specific heart/blood-flow measurements, which could help improve understanding and future care.
HsinchuAges 21 years+ - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT06556732RecruitingPhase 1
Eplerenone for preventing atrial fibrillation return
This trial is testing whether a medication called eplerenone can help prevent atrial fibrillation (AF) from coming back in people who have structural heart disease and have already had their heart rhythm restored to normal. It may be a good option if you are looking for a way to keep your heart in a normal rhythm.
AsyutAges 20–70 - NCT06854458Recruiting
Stress heart MRI for better diagnosis of heart artery disease
This study uses a special stress heart MRI to measure blood flow and find blockages in the arteries that supply your heart. It is for people with chest pain or abnormal EKG results who have risk factors for heart disease, to help doctors diagnose and treat coronary artery disease more accurately.
San Francisco, CaliforniaAges 35–85 - NCT06891456Recruiting
Pulsed field ablation for ventricular tachycardia after heart attack
This trial tests a new type of energy (pulsed field ablation) to treat a fast heart rhythm called ventricular tachycardia that happens after a heart attack. The goal is to stop the dangerous rhythm without damaging nearby healthy tissue.
Cleveland, OhioAges 18 years+ - NCT04983823Recruiting
Study aims to improve long-term heart effects after COVID
This trial looks at how persistent heart-related changes after a past COVID infection may be affected by study treatments. It mainly seeks people who are stable enough for follow-up visits and heart imaging, and who are not already on the specific heart medications required.
Melbourne, VictoriaAges 50–85 - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04927429Recruiting
MRI study to improve heart imaging
This trial helps develop and fine-tune MRI scans that look at the heart and blood vessels. It may help people with heart-related symptoms or conditions by improving how MRI images are created and interpreted.
Washington D.C., District of ColumbiaAges 18–100
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Common questions
- Are there clinical trials for valvular heart disease?
- Yes. Clin2 currently lists 117 recruiting valvular heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.