Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05604430Enrolling by invitation
Study of pre-hospital breathing support with a specific ventilator
This study looks at breathing support given outside the hospital using a particular ZOLL ventilator model and software version. If you were treated with the right equipment, the team will use the ventilator’s recorded data to evaluate how ventilation was delivered.
Hartford, ConnecticutAges Any age - NCT05368662Recruiting
Studying sleep and life quality in children on home ventilation
This study checks how sleep and overall quality of life change for children who use non-invasive breathing support at home. It also uses questionnaires to understand what helps or harms sleep and daily comfort so families and care teams can improve support.
Angers, Maine et LoireAges 6 months–17 years - NCT05405491Recruiting
DNA test to guide antibiotic use for pneumonia in ICU patients
This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.
LilleAges 18 years+ - NCT05279170Recruiting
Mask anesthesia with gentle throat pressure to prevent stomach air
This trial studies a way to hold gentle pressure near the throat during mask anesthesia (with or without a breathing tube) to reduce air going into the stomach. It may help lower the chance of “stomach insufflation” during elective surgery in young children.
LilleAges 2–10 - NCT05211661Recruiting
Diaphragm health during breathing machine support
This study looks at how the diaphragm (the main breathing muscle) changes when a person is on a breathing machine in the intensive care unit. It may help doctors understand how to better support breathing and recovery.
AachenAges 18–75 - NCT05117125Recruiting
Testing for markers in early ventilator lung infections
This study looks at changes (biomarkers) in the blood or other samples from people on a breathing machine. It may help doctors detect ventilator-associated pneumonia earlier and tailor treatment sooner.
DrammenAges 18 years+ - NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT02708836Recruiting
Tests safer airway method to reduce anesthesia “waking up” issues
This study looks at whether a combined airway method during general anesthesia can reduce unpleasant or risky “emergence” problems as you wake up. It is for people having planned laparoscopic (camera) surgery and who can follow fasting and consent rules.
Hershey, PennsylvaniaAges 18 years+ - NCT04186325Recruiting
Diaphragm training using ultrasound for ventilator patients
This study tests a way to train the diaphragm (the main breathing muscle) using ultrasound guidance to help people on breathing machines get stronger. It may help patients who are on a ventilator recover their breathing ability more effectively.
Al MansurahAges 21–65 - NCT07875530Recruiting
Comparing two anesthesia methods for obese patients having laparoscopic surgery
This trial compares two different anesthesia techniques for obese patients having laparoscopic surgery, to see which one works better and is safer.
Kocaeli, IzmitAges 18–65 - NCT07701096Enrolling by invitation
Home breathing support monitoring for advanced COPD
This study tests a home monitoring system that watches how well noninvasive breathing support (a mask that helps you breathe) works for people with severe COPD. The system sends early warnings to your care team if your breathing patterns change, which may help prevent flare-ups.
BeijingAges 18 years+ - NCT05136222Recruiting
Testing a night breathing machine setting for muscle-nerve disease
This study helps find the best night-time settings for a non-invasive breathing support device (a machine that helps breathing without a tube). It may help people with motor neurone disease start long-term breathing support more comfortably and effectively.
AdelaideAges 18 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT07867730Recruiting
Breathing exercises help people on ventilators with stiff lungs
This study tests two breathing exercises, inspiratory muscle training and positive expiratory pressure, for people in the ICU on a breathing machine. It aims to see if these exercises can improve breathing and recovery for patients with restrictive lung disease.
IslamabadAges 18–60 - NCT07854210Recruiting
High-flow nasal oxygen versus non-invasive ventilation for COPD
This trial compares two breathing support methods for people hospitalized with COPD and mild-to-moderate carbon dioxide retention. It aims to see if high-flow nasal oxygen is as effective as the standard mask-based ventilation.
Al Mansurah, Dakahlia GovernorateAges 40 years+ - NCT06030349Recruiting
Breathing support for kids with Down syndrome and sleep apnea
This trial looks at how well non-invasive breathing machines help children with Down syndrome who have obstructive sleep apnea. It tracks their health and sleep over time to see if the treatment works and improves daily life.
DublinAges 6 months–16 years - NCT05979545RecruitingPhase 4
Early treatment with ceftazidime-avibactam for serious infections
This study tests an antibiotic called ceftazidime-avibactam for people with serious infections like bloodstream infections or pneumonia that started in the hospital or from a breathing machine. It aims to start treatment quickly after identifying the bacteria.
Kuala LumpurAges Any age - NCT06321497Recruiting
Carbon dioxide removal to protect lungs during ARDS
This study tests a machine that removes carbon dioxide from your blood (called extracorporeal carbon dioxide removal or ECCO2R) to help protect your lungs from further damage while on a breathing machine. It may be an option if you have severe ARDS and your breathing machine settings are very high.
Frankston, VictoriaAges 18 years+ - NCT05664204Recruiting
ECMO before or after lung transplant to improve outcomes
This study looks at using a heart–lung machine (ECMO) to reduce complications and deaths after a lung transplant. It focuses on people getting a lung transplant who have certain types of lung-vessel (pulmonary) pressure problems.
ParisAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT07842510Recruiting
Controlled oxygen for copd flare-ups in the icu
This trial tests whether giving oxygen in a carefully controlled way (using a target range) works better than standard oxygen treatment for people in the ICU with a COPD flare-up. It aims to see if the controlled approach leads to better outcomes, like helping you recover faster.
Mahdia, Mahdia GovernorateAges 40 years+
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 506 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.