Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 525 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05801224Recruiting
Vascular ARDS recruitment after inhaled nitric oxide
This study tests whether giving nitric oxide gas through a breathing tube helps people with a lung condition called ARDS (acute respiratory distress syndrome) recover and leave the intensive care unit sooner. It may help some patients with mild-to-moderate cases who need a ventilator and a central line.
Boston, MassachusettsAges 18–80 - NCT06296173Recruiting
Lung-protective breathing tube removal after surgery
This study tests a special breathing tube removal method during surgery recovery to protect your lungs. It may help you breathe better after your abdominal surgery.
Vancouver, British ColumbiaAges 18 years+ - NCT07522346Recruiting
Ventilator Pressure Levels During Surfactant Therapy in Preterm Infants
This study tests whether different pressure levels used during a minimally invasive surfactant procedure (MIST)—a way to deliver lung-coating medicine without a breathing tube—affect how well preterm infants' lungs inflate. Researchers hope to find the best pressure settings to help babies breathe more easily.
Saint Albans, VictoriaAges 6 months–7 months - NCT06602557RecruitingPhase 2
Inhaled antibiotic for lung infection during ECMO support
This trial tests whether adding an inhaled antibiotic (amikacin) to standard IV antibiotics can better treat a serious lung infection (pneumonia caused by Gram-negative bacteria) in patients on a heart-lung machine (ECMO) and a breathing tube. If you or your loved one is on ECMO and has this type of pneumonia, this study may offer a new treatment approach.
ParisAges 18 years+ - NCT06563544Recruiting
Two ventilator settings for asthma and COPD patients
This study compares two different ways of delivering breaths from a ventilator for people with severe asthma or COPD. The goal is to see which method might be better for your lungs.
Rotterdam, South HollandAges 18–100 - NCT07758894Recruiting
Breathing without a breathing tube during heart transplant surgery
This study tests whether heart transplant surgery can be done while the patient is awake and breathing on their own, instead of using a breathing tube. If successful, it may lead to faster recovery and fewer complications.
Guangzhou, GuangdongAges 18 years+ - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06673862Enrolling by invitation
Detecting fluid needs with a breathing machine change
This trial checks if a simple change in ventilator settings (a tidal volume challenge) can predict whether you need more fluids, compared to a standard fluid challenge. It's for patients on a breathing machine who have low blood flow.
Banhā, Al-QalyubiaAges 18 years+ - NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT07052929RecruitingPhase 1/Phase 2
Gene therapy study for young boys with XLMTM on ventilators
This study tests a new gene therapy called ASP2957 in young boys with X-linked myotubular myopathy who are dependent on a ventilator. The goal is to see if it can help improve their breathing and muscle strength.
Chicago, IllinoisAges Up to 3 years - NCT07622563Recruiting
Automatic oxygen control for premature babies on breathing support
This trial tests a device that automatically adjusts oxygen levels for premature babies who need help breathing through tubes or masks in their nose. The goal is to keep oxygen levels in a safer, more stable range without needing staff to manually adjust it constantly.
LondonAges 5 months–8 months - NCT07575763Recruiting
CT scan vs standard sizing for breathing tubes in chest surgery
This study compares two methods for choosing the right size breathing tube for lung surgery: one uses a CT scan beforehand, the other uses standard sizing. The goal is to see which method works better and causes fewer complications.
AmmanAges 18 years+ - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT05539391Recruiting
Planning the best way to do emergency breathing tubes
This study tests an approach to improve how clinicians place an emergency breathing tube quickly and safely when someone is in serious breathing or life-threatening distress. It may help by standardizing care and optimizing medications and backup steps during urgent situations.
AngersAges 18 years+ - NCT05506904Recruiting
Help deciding when to remove a breathing tube
This trial studies a decision-support tool that helps ICU teams decide when it’s safe to try removing (extubating) a breathing tube. It may help reduce delays or avoidable re-intubation by guiding the timing of a low-support breathing trial (SBT).
Edmonton, AlbertaAges 18 years+ - NCT06832306Recruiting
Diaphragm pacing for breathing support in ICU
This trial tests a device that helps stimulate the diaphragm to improve breathing in patients who need a ventilator. It's for people with new breathing problems who have been in the ICU on a ventilator for less than 4 days.
La Jolla, CaliforniaAges 18 years+ - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT06925282Recruiting
Breathing help during airway surgery
This study looks at what factors make some patients need extra breathing support during airway surgery when using a special oxygen delivery method called THRIVE. The goal is to better understand who might need additional help to keep their oxygen levels safe.
SeoulAges 18 years+ - NCT06969443Recruiting
Studying rehab practices in the intensive care unit
This study watches how patients in the intensive care unit are helped to move and strengthen their muscles (rehabilitation) during their stay. It does not give any new treatment or medicine, but simply documents what usual care looks like for people who need a breathing tube for more than two days.
ParisAges 18 years+ - NCT06989385Recruiting
Studying breathing support failure in respiratory failure
This study looks at why some patients with acute respiratory failure do not improve with non-invasive breathing support like high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV). It aims to find patterns that might predict when these treatments are not enough.
ModenaAges 18 years+ - NCT06850844Recruiting
Ventilation management for abdominal laparoscopic surgery
This trial tests a personalized approach to setting ventilator pressure during laparoscopic abdominal surgery, using a special imaging belt to monitor lung function. It aims to reduce breathing complications after surgery, especially for patients at higher risk.
HanoiAges 18 years+
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 525 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.